International Journal of Pediatrics

Background: Leukemia is one of the most common malignancies in childhood, accounting for about 40 per million children under the age of 15 years. Acute lymphoblastic leukemia accounts ... Read More Background: Leukemia is one of the most common malignancies in childhood, accounting for about 40 per million children under the age of 15 years. Acute lymphoblastic leukemia accounts for about 75% of these cases of leukemia. Regarding the improvement in life expectancy and the prolonged life of patients with acute lymphoblastic leukemia, identifying the long-term complications and effects of treatment in patients is necessary.Methods: The present applied study is a cohort study based on the case-control method. In order to achieve the purpose of the study, 50 patients who had improved acute lymphoblastic leukemia were selected as a case group; the selections were conducted in a sequential manner in Mofid Children Hospital. 50 other people who had no history of ALL disease were selected as the control group. All information gathering processes including patient history, physical examination, and necessary tests were done by a pediatric hematology oncology subspecialties fellow and trained personnel with full supervision of Pediatric hematologist - oncologist. Blood samples were taken at 10-cc of fasting blood. Blood samples after centrifugation and storage at 20 ° C were used to measure serum fasting blood glucose, triglyceride (Slovak based on serum lipid profile), and insulin levels. All demographic information, BMI, clinical symptoms, laboratory tests, and treatments were recorded in both forms. Data were finally entered into SPSS version 21 and analyzed using the GEE method.Results: the incidence of obesity was significantly higher in patients with ALL as compared with the controls. The risk of obesity in ALL patients was found to be approximately 9 times higher than the controls. In this study 6 (12%) patients in cases and 4 (%8) patients in controls had metabolic syndrome. There was no statistically significant difference between the groups in the incidence of metabolic syndrome, insulin resistance, and visceral obesity.Conclusion: It is suggested that after acute lymphoblastic leukemia treatment in children, in addition to regular follow up for disease recurrence, the patients should be monitored about metabolic syndrome or any of its components, especially weight gain, and obesity.

The Association between Red Blood Cell Distribution Width and Metabolic Syndrome in Adolescent Girls

Mostafa Fazeli; Ali Reza Moslem; Zahra Meshkat; Ameneh Timar; Seyed-Amir Tabatabaeizadeh; Hamideh Ghazizadeh; Roshanak Ghaffarian Zirak; Meysam Moghbeli; Nadia Boroumand; Naghme jaberi; Mohammad Mohammadzadeh; Gordon A. Ferns; Hamid Reza Bahrami; Majid Ghayour-mobarhan

Volume 11, Issue 2 , February 2023, , Pages 17416-17427

https://doi.org/10.22038/ijp.2023.60826.4692

Abstract

Background: Metabolic syndrome (MetS) is characterized by metabolic and anthropometric abnormalities which are associated with an increased risk of cardiovascular disease (CVD). Red ... Read More

Clinical and Biochemical Predictors of Non-Alcoholic Fatty Liver Disease in Obese Children and Adolescents

Hoda Atwa; Jacklien Labib; Husseiny Abd-Allah; Ahmed Ibrahim

Volume 10, Issue 3 , March 2022, , Pages 15583-15593

https://doi.org/10.22038/ijp.2022.62321.4769

Abstract

Background: Obesity and its associated comorbidities are growing worldwide, including non-alcoholic fatty liver disease (NAFLD), which is one of the leading causes of chronic liver ... Read More

Evaluation of Neck Circumference as Potential Marker for Metabolic Syndrome in Children

Mostafa Fazeli; Mohammad Mohammad-Zadeh; Zahra Meshkat; Gordon Ferns; Hamidreza Bahrami-Taghanaki; Majid Ghayour-Mobarhan

Volume 9, Issue 6 , June 2021, , Pages 13865-13874

https://doi.org/10.22038/ijp.2020.52029.4137

Abstract

Background: Metabolic syndrome (MetS) is complicated condition especially in pediatrics. For better MetS definition, marker discovery are interested. More accurate simple indices may ... Read More

Association of Helicobacter Pylori Infection with Cardiometabolic Risk Factors among Iranian Adolescents: the CASPIAN III Study

Enayat Kalantar; Mohammand Javad Gharavi; Shervin Ghaffari Hoseini; Ramin Heshmat; Mojgan Oshaghi; Behnaz Gharegozlou; Hamid Asayesh; Armita Mahdavi Gorabi; Mohammad Esmaeil Motlagh; Mehdi Noroozi; Mostafa Qorbani; Roya Kelishadi

Volume 6, Issue 2 , February 2018, , Pages 7045-7054

https://doi.org/10.22038/ijp.2017.24411.2060

Abstract

Background: At least half the world’s population is colonized the stomach by Helicobacter pylori (H. pylori) which are a key constituent of the human microbiome. The aim of this ... Read More

The Relationship between Serum 25-hydroxyvitamin D Levels and Metabolic Syndrome in Birjand Children, East of Iran

Mahmood Zardast; Fatemeh Taheri; Ahmad Gholinejadan; Kokab Namakin; Seyedailreza Javadinia

Volume 4, Issue 5 , May 2016, , Pages 1759-1766

https://doi.org/10.22038/ijp.2016.6748

Abstract

Background: Metabolic syndrome (MS) is an important risk factor that is associated with vitamin D deficiency, according to recent studies. This study aimed to evaluate the relationship ... Read More

Propensity Score Application in the Relationship of Screen Time and Metabolic Syndrome in Adolescents: the CASPIAN-III Study

Nafiseh Mozafarian; Roya Kelishadi; Mohammad Esmaeil Motlagh; Mohammad Reza Maracy

Volume 4, Issue 3 , March 2016, , Pages 1491-1503

https://doi.org/10.22038/ijp.2016.6519

Abstract

Aim: This study aimed to assess the relationship of screen time and metabolic syndrome (MetS) among Iranian adolescents. Materials and Methods In this nationwide study, the ... Read More

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Keywords = Metabolic syndrome

Evaluation of Obesity, Insulin Resistance and Metabolic Syndrome in Childhood Leukemia Survivors

Abstract

The Association between Red Blood Cell Distribution Width and Metabolic Syndrome in Adolescent Girls

Abstract

Clinical and Biochemical Predictors of Non-Alcoholic Fatty Liver Disease in Obese Children and Adolescents

Abstract

Evaluation of Neck Circumference as Potential Marker for Metabolic Syndrome in Children

Abstract

Association of Helicobacter Pylori Infection with Cardiometabolic Risk Factors among Iranian Adolescents: the CASPIAN III Study

Abstract

The Relationship between Serum 25-hydroxyvitamin D Levels and Metabolic Syndrome in Birjand Children, East of Iran

Abstract

Propensity Score Application in the Relationship of Screen Time and Metabolic Syndrome in Adolescents: the CASPIAN-III Study

Abstract