Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Long-Term Survival of Peritoneal Dialysis in Children: A Cohort Study
10009
10017
EN
Mahmoud
Yousefifard
0000-0001-5181-4985
Prevention of Cardivascular Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
yousefifard20@gmail.com
Neamatollah
Ataei
0000-0001-9682-4394
Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Department of Pediatric Nephrology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
ataei_nm@yahoo.com
Shahin
Roshani
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
shahinroshani@ymail.com
Fatemeh
Darabi
Department of Public Health, Asadabad School of Medical Sciences, Asadabad, Iran.
f.darabi@gmail.com
Iraj
Najafi
Nephrology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
najafi266@yahoo.com
Mojtaba
Fazel
0000-0003-0463-4257
Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Department of Pediatric Nephrology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
mojtabafazel@yahoo.com
Zeynab
Talayi
Pediatric Department, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
talayiz@gmail.com
Michael
Jones
Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
michael.jones@icr.ac.uk
Mehdi
Yaseri
0000-0002-4066-873X
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
m.yaseri@gmail.com
Mostafa
Hosseini
0000-0001-7932-0047
1- Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.
2- Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
mhossein110@yahoo.com
10.22038/ijp.2019.41855.3525
<span style="font-family: Times New Roman;"><strong><em>Background: </em></strong>There is little information about the survival rate of pediatric peritoneal dialysis (PD) patients and its risk factors. Therefore, the aim of the present study was to assess survival rate and its risk factors in Iranian children undergoing PD. </span><br /> <span style="font-family: Times New Roman;"><strong><em>Materials and Methods: </em></strong>Demographic and laboratory data of 407 Iranian children (up to 19 years old) undergoing PD, from 20 centers in Iran were included. The outcome of interest in our study was survival rate and determination of its risk factors in PD children. The joint models of longitudinal and time-to-event data analysis was used. </span><br /> <span style="font-family: Times New Roman;"><strong><em>Results: </em></strong>The median duration of follow-up was 537 (interquartile range: 146 to 1,177) days. Finally, 72 (17.7%) patients died during a period of 23 years. Our results showed that one-year survival rate of PD patients was 93.6% and five-year survival rate was 76.9%. In addition, the most important risk factors for the PD all-cause mortality were age (HR=0.9301; 95% CI: 0.9031 to 0.9587), serum creatinine (HR=0.8907; 95% CI: 0.8138 to 0.9750), platelet count (HR=0.9999; 95% CI: 0.99995 to 0.99999), aspartate aminotransferase level (HR=1.0001; 95% CI: 0.9999, 1.0002), alkaline phosphatase (HR=0.9989; 95% CI: 0.9982 to 0.9997), renal solute clearance rate (HR=0.9839; 95% CI: 0.9700 to 0.9981), and normalized protein catabolic rate (HR=0.4031; 95% CI: 0.1879, 0.8648). </span><br /> <strong><em>Conclusion: </em></strong>The survival rate of Iranian pediatric PD patients is similar to other countries. It is suggested that laboratory assessment be continually
Children, Mortality, Peritoneal Dialysis, Survival,Risk factors
https://ijp.mums.ac.ir/article_13502.html
https://ijp.mums.ac.ir/article_13502_03823f4c3fd9d5d3b32a71432afed869.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Validity of Peripheral Capillary Oxygen Saturation and Normal Mixed Venous Oxygen Tension in Measurement of O2 Content
10019
10027
EN
Nemat
Bilan
0000-0002-1849-4462
Pediatric Pulmonologist, Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
bilannemat@yahoo.co.uk
Elnaz
Eskandartash
Fellowship of Pediatric Pulmonology, Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
10.22038/ijp.2019.41833.3522
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">The change in venous oxygen saturation occurs earlier, and even its reduction is faster than arterial oxygen saturation. The aim of this study was to validate SvO<sub>2</sub> and PvO<sub>2</sub> for O<sub>2</sub> content measurement in children hospitalized with respiratory distress.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">In this cross-sectional study, 80 children who were admitted with respiratory distress were included in the study according to the study inclusion and exclusion criteria. Baseline characteristics such as age and gender were recorded in the data collection form, designed by the researcher. In order to determine the amount of SaO<sub>2</sub> and PaO<sub>2</sub> the arterial blood sample was prepared, venous blood sample was prepared to determine the amount of hemoglobin, SvO<sub>2</sub> and PvO<sub>2</sub>. The gold standard for the determination of O<sub>2</sub> content was the arterial blood sample. All samples were examined by a blood gas analyzer and then calculated using the formula of O<sub>2</sub> content values. For SvO<sub>2</sub> and PvO<sub>2</sub> validation, we used diagnostic analysis methods including sensitivity, specificity, positive and negative predictive values. Cut-point value for SvO<sub>2</sub> and PvO<sub>2</sub> were 76.50 and 44.30, respectively. </span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">In this study, the patients’ mean age was 5.15 ± 4.20 years. 62.5% (n=50) were male and 38.5% (n=30) were female. The values of arterial and venous O<sub>2</sub> content were 14.13 ± 3.05 and 11.95 ± 3.04 from a total of 80 patients. SvO<sub>2</sub> and PvO<sub>2</sub> for measuring O<sub>2</sub> content had a sensitivity of 80.5 and 71.80%, respectively, and specificity of 80.5 and 78%, respectively.</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">SvO<sub>2</sub> and PvO<sub>2</sub> have good validity for evaluating O<sub>2</sub> content in patients admitted to PICU. So that SvO<sub>2</sub> had a sensitivity and specificity of over 80%, and PvO<sub>2</sub> had a sensitivity and specificity of over 70%.</span>
Children,respiratory distress,SvO2,PvO2,Oxygen Content,Validity
https://ijp.mums.ac.ir/article_13539.html
https://ijp.mums.ac.ir/article_13539_39543fba97bf88e1eb28f7173dd748a2.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Evaluating the Short-Term Outcome of Mechanically Ventilated Neonates Admitted to the Neonatal Intensive Care Unit of Besat Hospital, Hamadan, Iran
10029
10034
EN
Amir Reza
Monsef
0000-0001-8999-2250
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
monsef_a@yahoo.com
Fatemeh
Eghbalian
0000-0002-2621-327X
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
eghbalian_fa@yahoo.com
Mohammad Kazem
Sabzehei
0000-0001-5304-3512
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
mk_sabzehei@yahoo.com
Elham
Khanlarzade
0000-0003-3265-4570
Department of Community Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
khanlarzadeh@yahoo.com
10.22038/ijp.2019.41629.3507
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">Many neonates admitted to Neonatal Intensive Care Unit (NICU) need mechanical ventilation for recovery. This study was designed to evaluate the short-term outcome of mechanically ventilated neonates admitted to NICU. </span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">In this descriptive cross-sectional study, all the neonates in need of mechanical ventilation in NICU of Besat Hospital, Hamadan, Iran, were enrolled for one year from September 2017 to September 2018. The selected data were of neonatal age at admission time, birth weight, gender, gestational age, indications of mechanical ventilation, lab results, length of hospital stay and the outcome of the disease were extracted from the medical file and analyzed using SPSS software (version 22.0). </span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">Of 141 mechanically ventilated neonates, 55.3% (n=78) were males. The mean of neonatal age, mean gestational age and mean birth weight were, 4.67 ± 6.58 days, 35.51 ± 3.88 weeks, and 2779.37 ± 827.06 g, respectively. RDS (58.9%) was the most common indication for mechanical ventilation. The overall rate of neonatal recovery was 51.8%. The results of unilabiate analysis showed a significant relationship between indications of mechanical ventilation, gestational age, neonatal birth weight, acidosis (pH <7.1), duration of mechanical ventilation, duration of hospitalization and the disease outcomes (P<0.05).</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">The results of this study showed that respiratory distress syndrome, low gestational age and birth weight, acidosis and duration of mechanical ventilation would lead to increased death in mechanically ventilated neonates.</span>
outcomes,Mechanical Ventilation,neonate,Neonatal Intensive Care Unit
https://ijp.mums.ac.ir/article_13501.html
https://ijp.mums.ac.ir/article_13501_134a9ed999b69d0c68b87ade76a7edb7.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Evaluation of Serum Levels of Calprotectin in Asthmatic Children
10035
10041
EN
Abdelhakeem
Abdel Mohsen
0000-0001-8108-0660
Associate Professor of Pediatrics, Departments of Pediatrics, El-Minia University, Mina, Egypt.
aboueyad1@yahoo.com
Ahmed
Abdelfadel
Associate Professor of Clinical Pathology, Department of Clinical Pathology, El-Minia University, Mina, Egypt.
ahmedabdelfadeel@yahoo.com
10.22038/ijp.2019.41484.3498
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">Calprotectin is a cytosolic protein that belongs to the S-100 protein group with immunomodulatory and antiproliferative actions. The level of this protein increases in infection, inflammation, and malignancy. The aim of this study was to evaluate the level of calprotectin in asthmatic children as indicator of asthma severity. </span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">This is a prospective study that included forty-five children with bronchial asthma and admitted to pediatric department, Minia University Children’s Hospital, Egypt, they were (15 intermittent asthma, 15 mild persistent asthma and 15 moderate persistent asthma), and 20 apparently healthy children were included in the study and subjected to thorough history taking, full clinical examination, lung function test, CBC, Immunoglobulin E and measurement of serum levels of calprotectin using ELISA. </span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">The study revealed a statistically significant increase in the level of calprotectin in asthmatic children compared to that of the control group (p<0.000). Also, there was a significant increased level of calprotectin in children with persistent asthma compared to those with mild intermittent asthma and control group (p<0.001). In addition, there was a positive correlation between serum level of calprotectin and eosinophil count (r=0.83, p=0.001), and negative correlation with lung functions (FEV1 and PEEF) (r=-0.89 and r=- 0.88, respectively, p<0.05). </span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">Increased levels of calprotectin in asthmatic children suggest that it may play a role in asthma, also it was associated with poor lung functions suggesting that there is a close relation between calprotectin level and the severity of childhood asthma. </span>
Asthma,calprotectin,Children,Immunoglobulin E,Pulmonary functions tests
https://ijp.mums.ac.ir/article_13457.html
https://ijp.mums.ac.ir/article_13457_fd30ec4b5ade93d3c2c3fbf54eaff2d1.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Prevention Strategies and Guidelines to Manage Obesity in Children and Young People
10043
10047
EN
Khetam
Al-Awamreh
0000-0003-1398-3053
Assistant Professor, Department of Maternal and Child Health Nursing, Princess Salma Faculty of Nursing, AL al-Bayt University, P.O. Box 130040, Mafraq, 25113, Jordan.
al-awamreh.k@aabu.edu.jo
Abdullah
Alkhawaldeh
0000-0002-1146-0972
Associate Professor, Faculty of Nursing, Jerash University, Amman - Irbid International Street 26150 Jerash, Jordan.
dr-abd@jpu.edu.jo
Sami
Aloush
Assistant Professor, Princess Salma Faculty of Nursing/Al Al-Bayt University, Adult Healthcare Nursing Department, P.O. Box130040, Mafraq, 25113, Jordan.
sma91@case.edu
Intima
Alrimawi
PhD, MSN, MPH, BSN (RN), Associate Nursing Program Director, Stratford University, USA.
intimarimawi@yahoo.co.uk
Mohammad
Al Qadire
Assistant Dean for Students Affairs, Head of Adult Healthcare Nursing Department, Princess of Salma Faculty of Nursing, Al Al-Bayt University, P.O. Box 130040 Mafraq 25113, Jordan.
mohammadqadire@abbu.edu.jo
Mohammad
Suliman
Associate Professor, Princess Salma Faculty of Nursing, Community and Mental Health Department, Al Al-Bayt University, Mafraq, Jordan.
mbarahemah@aabu.edu.jo
Manar
Al-Azzam
Associate Professor, Al-Albayt University/Princess Salma Faculty of Nursing, Mafraq, Jordan.
manar-alazzam@uiowa.edu
Omar
Khraisat
Assistant Professor, Faculty of Nursing, Jerash University, Jordan, P.O. Box 26150 Jerash, Jordan.
khraisat1111@hotmail.com
Moawiah
Khatatbeh
Associate Professor of Public Health, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
moawia.m@yu.edu.jo
Mohammed
ALBashtawy
Full Professor, Community and Mental Health Department, Princess Salma Faculty of Nursing, AL al-Bayt University, Jordan.
mohammadbash@aabu.edu.jo
10.22038/ijp.2019.40813.3447
<span style="font-family: Times New Roman;">Obesity in children and young people is a significant public health issue. It can be associated with adverse health, economic and social implications. It is argued that preventing obesity needs adaptation to a healthy lifestyle, which includes behavioral modification, reduction in sedentary behavior, changes in nutrition, managing stress and increased physical activity. Families, healthcare professionals, school nurses, policy makers, researchers, and the community share responsibilities to prevent and manage obesity in children and young people.</span>
Children,Obesity,recommendations,young people
https://ijp.mums.ac.ir/article_13458.html
https://ijp.mums.ac.ir/article_13458_aaf40a329abf47f47d723a75565d7d3e.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran
10049
10056
EN
Nahid
Najafi
0000-0001-7822-2680
Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
nahid.najafii1987@gmail.com
Elahe
Amini
0000-0002-4005-9563
NICU Division, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
s_khazaeii@yahoo.com
Khadije
Daneshjou
Department of Pediatrics, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
daneshjou1981@gmail.com
Hossein
Pesarakli
Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
pesarakli.h@yahoo.com
Mahnaz
Akbari
Department of Pediatrics, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
mahnaz1330@yahoo.com
10.22038/ijp.2019.40474.3422
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">There are contradictory results regarding association between maternal HIV infection and neonatal adverse outcomes. Therefore, in this study the neonates born from HIV-positive mothers compared with HIV-negative mothers were assessed in Tehran, Iran.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">This retrospective case-control study was conducted on 50 infants born to an HIV-positive mother compared with 53 infants born to an HIV-negative mother as control group, during 8 years of a period from 2006-2015, admitted in Valiasr Hospital of Tehran. Data were gathered from medical records of patients.</span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">All children (n=53, 100%) in the case group were born through cesarean section; while 20.75% of the control group children were born by natural delivery (P=0.001). There was statistically significant difference between neonates born from HIV-positive mothers compared to HIV-negative mothers with respect to delivery method and gender (P<0.05). The mean weights (gr) were higher in the controls than the cases (3052.830±380.71 vs. 2731.80±575.90) (P=0.001). Also, a significantly increased Hemoglobin was observed in the controls (15.87±1.97 g/dL) compared to the cases (13.42±1.69 g/dL) (P=0.001). Liver functions test (LFTs)was significantly higher in case groups (P=0.005).</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">Based on the results,the mean weight and hemoglobin were lower in infants born from HIV-positive women compared with HIV-negative women. Also, LFT Disorder was higher in infants born from HIV-positive women compared with HIV-negative women. </span>
Aids,Infant,HIV,Mother
https://ijp.mums.ac.ir/article_13208.html
https://ijp.mums.ac.ir/article_13208_4cfc62222b045bcaca1b0cd32ef07b69.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Evaluation of Electrocardiographic Parameters in Diabetes Mellitus Type I in Children and Adolescent
10057
10066
EN
Noor Mohammad
Noori
0000-0002-0732-6412
Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
dr_noori_cardio@yahoo.com
Alireza
Teimouri
0000-0002-8356-4260
Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
alirezateimouri260@gmail.com
Maryam
Nakhaee Moghadam
0000-0002-0080-862X
Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
maryamnakhaey@yahoo.com
Maryam
Kasravi
School of Medicine, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
dr_maryam_kasravi67@yahoo.com
10.22038/ijp.2019.40337.3417
<br /> <strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <br /> <span style="font-family: Times New Roman;">Cardiovascular complications are continuing to be a major cause of morbidity and mortality in diabetes mellitus type I (DMTI). The study aimed to evaluate the rate of changes in ECG parameters in children with DMTI compared with healthy children.</span><br /> <br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <br /> <span style="font-family: Times New Roman;">This case-control study was performed on 140 participants which consisted of 70 patients with DMTI (case group) matched in sex and age with 70 healthy ones (control group) in two centers in collaboration with Ali Asghar Hospital, Zahedan, Iran, between March 2017 and April 2018. Electrocardiography was performed in all participants (patients and healthy), and heart rate, QT (start of the Q wave and the end of the T wave) QTc interval (QT/</span><span style="font-family: Times New Roman;"><em><strong>√</strong></em> RR), QTd (dispersion between maximum and minimum of QT), and QTcd (dispersion between maximum and minimum of QTc) were measured. Duration of diabetic and level of HbA1c were obtained for patients and the effects of these parameters on ECGs were investigated. </span><br /> <br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <br /> <span style="font-family: Times New Roman;">Height, weight and heart rate were higher in the patients (P<0.001) when S in V<sub>1</sub> was higher in case (6.16±3.23) compared to the control group (4.33± 2.22) (P<0.001). QT (356.71±27.28 compared to 347.00±23.55), QTd (49.00±14.66 compared to 41.21±8.32), and QTcd (60.47±17.32 compared to 49.93±10.44) were higher in case group (p<0.05). Hemoglobin A1C (p=0.043) was higher in boys and heart rate was higher in girls (p<0.001). Diabetic time duration and HbA<sub>1c</sub> normality states did not change the length of these parameters in diabetic patients. </span><br /> <br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <br /> <span style="font-family: Times New Roman;">Based on the results, QT, QTd, QTc and QTcd were higher in patients with DMTI. Diabetic time duration and HbA1c states did not change the ECG parameters in diabetic patients. </span><br />
Adolescents,Children,Diabetes Mellitus,QT changes
https://ijp.mums.ac.ir/article_13219.html
https://ijp.mums.ac.ir/article_13219_c11b725748bb458669ca75c162e3f64f.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Factors Affecting Child Labor in Iran: A Systematic Review
10067
10075
EN
Sara
Ghahremani
0000-0002-7343-0429
Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.
Shahrzad
Khosravifar
Psychiatrist, Fellowship of Sleep Medicine, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Masumeh
Ghazanfarpour
0000-0003-4639-3711
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
masumeh.ghazanfarpour@yahoo.com
Zahra
Sahraei
Bahar Hospital, Shahroud University of Medical Science, Shahroud, Iran.
Abdolhadi
Saeidi
Social Work, Lmam Khomeini Hospital of Mahabad, Urmia University Of Medical Sciences, Mahabad, Urmia, Iran.
Hamed
Jafarpour
Student Research Committee. Faculty of medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Shaghayegh
Khosravifar
Resident of Psychiatry, Isfahan University of Medical Science, Isfahan, Iran.
Firoozeh
Mirzaee
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Masoudeh
Babakhanian
0000-0002-6128-8023
Social Determinants of Health Research Center, Semnan University Of Medical Sciences, Semnan, Iran.
10.22038/ijp.2019.41689.3510
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">For decades, child labor has been an important global issue associated with inadequate educational opportunities, poverty and gender inequality. In order to make effective policies to reduce child labor it is important to understand the specific factors that affect it. We aimed to investigate the main factors affecting child labor n Iran.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">There are authoritative websites on the topic of working children in Iran, including the WHO, UNFPA, UNDP, Web of Science, ProQuest, Medline, Scopus, and CINAHL databases for reviewing studies conducted in Iran. Articles from internal dissertations and Google's databases, SID, Magiran, and Iran Doc during the period 1985 to June 2019 were included. Quality of studies was reviewed by the STROBE checklist. Information was extracted by two blind researchers.</span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">A total of 9 studies were identified (including 17, 219 on child labor), the majority of which were cross-sectional. Affecting factors on child labor and Street children were grouped into four categories such as "Family problems", "Urbanization", "Social and Cultural", and "Personality". </span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">In the contemporary Iranian society, many children, for some reasons including personal, family, social and cultural, and urbanization problems, are involved with important social damages such a child labor. These factors make children vulnerable and endanger the health of the community. </span>
Children,labor,Iran,Systematic review
https://ijp.mums.ac.ir/article_13451.html
https://ijp.mums.ac.ir/article_13451_f0678e429a884fcec7b3a830cd1c0774.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Pathology of Cyberspace: A Study of the Detrimental Effects of Mobile Phones on Students' Psychological Well-being
10077
10085
EN
Marzieh
Kaboudi
0000-0002-5746-1153
Department of Reproductive Health, Nursing and Midwifery Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran.
f_kaboudi@kums.ac.ir
Manoj
Sharma
Behavioral and Environmental Health, School of Public Health, Jackson State University, Jackson, MS, USA.
manoj.sharma@jsums.edu
Arash
Ziapour
orcid.org/0000-0001-
PhD Student, Health Education and Health Promotion, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
arashziapoor@gmail.com
Fateme
Dehghan
0000-0002-0768-1334
Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
fatemedehghan1368@gmail.com
Parvin
Abbasi
0000-0002-9752-8244
Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
pabasi2003@yahoo.com
10.22038/ijp.2019.39704.3381
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">In addition to their widespread applications in various fields, cellular phones have some inappropriate social consequences, including psychosocial addiction, degradation of values, reduced social interactions, early maturity and endangering the psychological well-being of users. Therefore, the present study aimed to investigate detrimental effects of Mobile phones on the psychological well-being of second grade students. </span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">In this cross-sectional study, the sample population included 269 second grade students (107 boys and 162 girls) in Kermanshah, Iran in 2018 and being in the 10-18 age-range who were selected using cluster sampling. As for data collection, the Jenaro’s Cell-Phone Over-Use scale and Ryff’s psychological well-being scale were utilized, which were filled out by the students themselves. </span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">The results of the present study demonstrated that the means of the deleterious use of mobile phones and psychological well-being measured 44.71±16.45 (total score=126), and 63.86±14.43 (total score=84), respectively. The results also indicated that the observed F (F=10.12) was significant at p<0.005, and the predictor variables together explained 0.33 of the variance of psychological well-being. Moreover, it was shown that the deleterious use of mobile phones and psychological well-being significantly and negatively correlated at p<0.005, r=0.49.</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">According to this study, it was revealed that the deleterious overuse of mobile phones and psychological well-being were significantly and negatively correlated; which means that the higher the use of mobile phones, the more vulnerable the psychological well-being becomes.</span>
effects,Mobile Phone,Students,Well-Being
https://ijp.mums.ac.ir/article_13123.html
https://ijp.mums.ac.ir/article_13123_1ae98ac5109b8e14b9e18a6e6f2c9c7b.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Medicinal Herbs Useful in Pediatric Fever from the Perspective of Persian Medicine
10087
10098
EN
Fatemeh
Hadian
0000-0001-9942-3748
Department of Traditional Medicine, Faculty of Traditional Medicine, Tabriz University of Medical Science, Tabriz, Iran.
f.hadian1985@gmail.com
Mojtaba
Varshochi
0000-0003-3740-5370
Professor, Infectious and Tropical Disease Research Center, Tabriz University of Medical Science, Tabriz, Iran.
varshochimo@gmail.com
zohre
Feyzabadi
School of Persian and Complementary Medicine, Mashhad University of Medical Science, Mashhad, Iran.
feyzabadi_8823@yahoo.com
Arman
Zargaran
Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
zargarana@sums.ac.ir
Mehdi
Besharat
Department of Infectious Disease, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
besharatsearch@yahoo.com
Mojtaba
Mousavi Bazaz
Department of community Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
mousavim@mums.ac.ir
10.22038/ijp.2019.41502.3500
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">Fever is the most important and common symptom of pediatric diseases. Fever can be a sign or symptom or complication of disease. Considering the development of complementary and alternative medicine worldwide and the prevalence of this symptom in children, we aimed to investigate their application based on </span><span style="font-family: Times New Roman;">Persian</span><span style="font-family: Times New Roman;"> medical textbooks by searching herbs used in pediatric fever.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">In this review study, materials were extracted by searching in reliable Persian medical textbooks of the10<sup>th</sup> -20<sup>th</sup> century using related Persian medicine keywords. Then the documentations for herbs extracted were searched in the databases based on the conventional medicine. The interpretation was made based on the results.</span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">Based on the Persian medical textbooks, seventeen herbs have been prescribed for decreasing pediatric fever. Among them, 16herbs have proven mechanisms of action for treatment of fever, classified into five categories (diaphoretic, anti-inflammatory, anti-septic, immunomodulatory, anti-oxidant) based on literature review. On the other hand, according to Persian medicine, there were thirteen cold temperament herbs and only four hot temperament ones. They were administrated using various oral and topical methods. The maternal and neonatal treatment was emphasized.</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">According to this study and documentations of conventional medicine, many of these herbs can be effective in the treatment of pediatric fever, so further clinical studies are recommended for evaluating their efficacy.</span>
Fever,Herbal Medicine,Pediatric,Persian Medicine,Medicinal Plants
https://ijp.mums.ac.ir/article_13525.html
https://ijp.mums.ac.ir/article_13525_2fbd3a3774f015f05ee325fe55cb2c11.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Acute Hepatorenal Dose Dependent Toxicity of Teucrium Polium Hydro Alcoholic Extract in Rat
10099
10107
EN
Tayyeb
Ghasemi
0000-0002-1396-2706
Basic Electrophysiology Research Centre, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
scince.tgb@gmail.com
Mansoor
Keshavarz
Basic Electrophysiology Research Centre, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
keshavarzm@tums.ac.ir
Mohsen
Parviz
0000-0003-4478-6888
Basic Electrophysiology Research Centre, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
mohsenparviz110@gmail.com
10.22038/ijp.2019.41222.3475
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">Based on vast usage of teucrium polium (TP) in alternative medicine of developing countries for treatment of ailments in children and adults, this study is designed to examine acute hydro alcoholic extract of TP effects in different doses on rat liver and kidney functions and tissue structures. </span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">Animals were given daily intraperitoneal (i.p.) injection of TP at 3, 10, 30, 100, and 200 mg/kg or equal volume of normal saline for a week. One-hour postprandial blood glucose at day 1 and day 7, liver enzymes, serum creatinine (Cr), blood urea nitrogen (BUN) and hepatorenal tissues were examined at the end of the study. Animal body weights were also measured on a daily basis.</span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">TP at 3, 10, 30 and 100 mg/kg body weight didnot affect functional and structural characteristics in rat liver and kidney tissues compared with control animals. However, at high 200 mg/kg dose, it provoked liver and kidney tissue damages together with significant rise in aspartate aminotransferase (p<0.001), alanine aminotransferase</span><span style="font-family: Times New Roman;"> (p=0.001), Cr (p=0.001), and BUN (p=0.001). Animal body weight in each group under TP pretreatment protocol unchanged during the study except at high 200 mg/kg which showed a significant weight loss (p<0.001).</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">TP detrimental health effects especially on liver and kidney tissues are frequently overemphasized, but in adose-dependent manner. However, we also believe TP has potential medical benefits and can find a way to the medical arena if thorough conducted researches can determine its toxic components and isolate appropriate derivatives for ensuing use. </span>
Iranian Traditional Medicine,liver toxicity,kidney toxicity,Teucrium polium
https://ijp.mums.ac.ir/article_13340.html
https://ijp.mums.ac.ir/article_13340_5ac56d2f7d0f8fb7462275a56ba0d841.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Efficacy of Cold Therapy and Passive Stretching to Improve Gait in Spastic Diplegic Cerebral Palsy Children
10109
10118
EN
Chinnavan
Elanchezhian
0000-0002-5408-4030
Research Scholar, Department of Rehabilitation Science, Holy Cross College, India.
elanchezhianrehab@gmail.com
P
Swarnakumari
0000-0002-6683-5743
Associate Professor, Department of Rehabilitation Science, Holy Cross College, India.
swarnaravichandran@gmail.com
10.22038/ijp.2019.41071.3461
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">One of the most common causes of severe physical disability in childhood is cerebral palsy (CP). Mobility is one of the most important functions to fulfill the activities of daily living. We aimed to determine the effectiveness of cold application to improve the ambulation in spastic diplegic CP children.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods </span></em></strong><br /> <span style="font-family: Times New Roman;">In this clinical trial study, 40 subjects were included for the study. They were divided into two groups, namely experimental (n=20), and conventional group (n=20). Study was carried out in Holy Cross College, Department of Rehabilitation Science, Tiruchirappalli, India. Conventional group was given regular conventional training and experimental group was given cold therapy, passive stretching in both legs before training. Both groups received training for 45 minutes, 3 times a week for a duration of 6 weeks. Modified Ashworth scales were used to measure spasticity step length, stride length and Cadences were used to measure the gait parameters, and Timed Up and Go test (TUG) was used to measure the functional activity. </span><br /> <strong><em><span style="font-family: Times New Roman;">Results </span></em></strong><br /> <span style="font-family: Times New Roman;">Significant effect was observed in decrease in spasticity, there was increase in gait parameters and timed up and go test in two studied groups. The post-test mean values of all the variables of cold therapy, passive stretching in experimental group are improved compared with that of conventional group. The experiment improved with stride length, step length, cadence, timed up and go test and Modified Ashworth scale (p<0.05). </span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">Based on the derived results, there was decreased tone in spastic muscles and improvement in gait parameters and functional ability in children with diplegic CP after application of cold therapy and passive stretching.</span>
Children,Cold therapy,Diplegic Cerebral palsy,spasticity,Gait,Passive stretching
https://ijp.mums.ac.ir/article_13536.html
https://ijp.mums.ac.ir/article_13536_0deb201271eae889b824e406f248382c.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Gyrate Atrophy of the Choroid and Retina: A Case Report
10119
10123
EN
Somayyeh
Hashemian
0000-0001-6760-4093
Department of Pediatric Endocrinology and Metabolism, Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
hashemians951@mums.ac.ir
Rahim
Vakili
0000-0002-7707-7052
Department of Pediatric Endocrinology and Metabolism, Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran AND
Medical Genetic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
vakilir@mums.ac.ir
Azadeh
Zare Feizabadi
0000-0002-8245-6647
Department of Pediatric Endocrinology and Metabolism, Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
zarefa951@mums.ac.ir
10.22038/ijp.2019.36478.3179
<span style="font-size: x-small;">Introduction</span><br /> <span style="font-size: x-small;">Gyrate atrophy of the choroid and retina is a metabolic disorder, which is inherited in an autosomal recessive pattern. Although gyrate atrophy is rare, it is concerning as it results in blindness. It is characterized by hyperornithinemia, retinal atrophy, leads to progressive myopia and tunnel vision, and Posterior Subcapsular Cataracts. Patients have lower amounts of ornithine aminotransferase. </span><br /> <span style="font-size: x-small;">Case Report</span><br /> <span style="font-size: x-small;">In this study, we report a 17-year-old boy referred to our hospital by an ophthalmologist, with progressive visual loss from 7 years of age. The eye examinations manifested chorioretinal degeneration and high myopia. In lab data, plasma ornithine amount was elevated 10-fold higher than normal. By this finding, he was diagnosed as having Gyrate Atrophy.</span><br /> <span style="font-size: x-small;">Conclusion</span><br /> <span style="font-size: x-small;">Treatment with pyridoxine and low arginine diet can reduce the ornithine plasma level in Gyrate Atrophy. Our report is to describe the first case of gyrate atrophy in pediatric endocrinology department in Iran diagnosed by biochemistry and treated with pyridoxine and low arginine diet.</span>
Adolescent,Coronary artery aneurysm,Idiopathic aneurysm,Cardiac catheterization
https://ijp.mums.ac.ir/article_12175.html
https://ijp.mums.ac.ir/article_12175_54952f00dbf750c20d61c53c82fe92aa.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Advantages and Disadvantages of Methadone among Children and Adults: A Systematic Review and Meta-Analysis
10125
10137
EN
Masoudeh
Babakhanian
0000-0002-6128-8023
Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Kaveh
Mousavi Kani
0000-0003-1062-7053
Head and Neck Research Center, Facial plastic surgery division, Tehran University of Medical Science, Tehran, Iran.
kavehmed@gmail.com
Hoda
Shojaei
0000-0002-6343-7299
Pediatrician, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Robabeh
Mousavi nezhad
Pediatrician, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
moosavinezhad_s@yahoo.com
Farida
Daneshvar Mozaffari
Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran.
Kourosh
Sayehmiri
Psychosocial Injouries Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Shahrzad
Khosravifar
Psychiatrist, Fellowship of Sleep Medicine, Rasool Akram Hospital, Iran University of Medical Science, Tehran, Iran.
Shaghayegh
Khosravifar
Resident of Psychiatry, Isfahan University of medical science. Isfahan, Iran.
Abolfazl
Fattah
0000-0001-5477-7745
Semnan University of Medical Science, Semnan, Iran.
Masumeh
Ghazanfarpour
0000-0003-4639-3711
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
masumeh.ghazanfarpour@yahoo.com
Firoozeh
Mirzaee
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
10.22038/ijp.2019.41697.3511
<br /><span style="font-size: x-small;">Background: Today, an increasing trend to methadone as an alternative maintenance treatment for opiate dependence in adults is observed; children for both intentional and accidental reasons are exposed to serious and fetal effects of methadone. We aimed to investigate effects of methadone on children and sexual functioning among adults in Iranian population.</span><br /><span style="font-size: x-small;">Materials and Methods: An extensive search was done in databases of Medline, EMBASE, Scopus, Cochrane, and Web of Science until August 2018. Two independent researchers screened articles, and categorized them based on the evaluated outcomes and overall effect size was presented. After excluding the duplicated, irrelevant and low-quality articles, eligible ones were enrolled in the meta-analysis. Finally, pooled effect size was presented as standardized mean difference (SMD) or pooled prevalence with 95% confidence interval (95% CI). </span><br /><span style="font-size: x-small;">Results: Methadone was found to be more effective than morphine on neonatal abstinence syndrome. The first four most common symptoms of methadone poisoning were loss of consciousness (81%), sleepiness (72%), meiotic pupils (76%), vomiting (56%), and Apnea (48%). The overall prevalence rate of sexual disorders and erectile dysfunction was 66.3% and 77.5%, respectively. The subjects in methadone group were over 2.5-fold more likely to use condom during intercourse (p<0.001). The methadone therapy could lead to a significant reduction in orgasm functioning (p<0.001), and a significant improvement in libido (p=0.001). The methadone maintenance treatment (MMT) significantly resulted in decreased orgasm function and improved libido in males.</span><br /><span style="font-size: x-small;">Conclusion: Evidence suggests a positive impact of methadone maintenance treatment on risky sexual behaviors. Regarding the methadone poisoning effect on children, people should be informed by health care providers about serious and fetal effects on children.</span>
Children,Iran,methadone,Meta-analysis,Poisoning,Sexual functioning
https://ijp.mums.ac.ir/article_13507.html
https://ijp.mums.ac.ir/article_13507_9b927972316afe84fea90f45717c7858.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
The Relationship between Medication Errors with Job Satisfaction of Nurses in Pediatric Ward
10141
10153
EN
Fatemeh
Hajibabaee
0000-0002-5176-8816
Assistant Professor, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
hajibabaeefateme@yahoo.com
Masoomeh
Salehi Kamboo
MSc in Nursing, Nursing & Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
masoome_salehi@yahoo.com
Somayeh
Faghanipour
PhD Candidate of Nursing, School of Nursing, University of Toronto, Centre for Biomedical Ethics and Law, KU Leuven, Belgium.
faghanipour@gmail.com
Hadis
Ashrafizadeh
0000-0002-9369-5854
PhD Student of Nursing, Nursing and Midwifery School, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
ashrafizadeh.h1993@gmail.com
Mohamad Hossein
Haghighi Zadeh
MSc in Statistics, Ahvaz Jundishapur University of Medical Sciences. Ahvaz, Iran.
haghighizadeh@ajums.ac.ir
10.22038/ijp.2019.40926.3450
<span style="font-size: x-small;">Background </span><br /> <span style="font-size: x-small;">Medication errors are known as a preventable cause of idiopathic damage in pediatrics. These errors could entail serious direct and indirect outcomes that often lead to disruptions in the health care system. The present study aimed to determine the relationship between medication errors with job satisfaction of nurses in pediatric ward.</span><br /> <span style="font-size: x-small;">Materials and Methods </span><br /> <span style="font-size: x-small;">This cross-sectional, descriptive-analytical study was conducted on 80 nurses working in pediatric wards in hospitals affiliated with Ahwaz University of Medical Sciences, Iran that were selected by census. The questionnaires of medication administration error and nurses' job satisfaction (Minnesota job satisfaction) by purposive sampling were used for gathering data. Validity and reliability were checked for internal consistency and stability.</span><br /> <span style="font-size: x-small;">Results</span><br /> <span style="font-size: x-small;">Mean nurses’ medication errors in pediatric wards for every nurse over a 3-month period was 11.41<span style="text-decoration: underline;">+</span> 11.79 cases, and mean error reporting was 1.97<span style="text-decoration: underline;">+</span> 3.92 cases. Nurse’s age (P≤0.01) and education level (P≤0.03) were statistically significantly related with medication errors. The findings of job satisfaction of nurses showed that 44.07% of nurses were dissatisfied. However, there was no significant relationship between incidence of medication errors and nurses’ job satisfaction (r= -0.167, P= 0.138).</span><br /> <span style="font-size: x-small;">Conclusion</span><br /> <span style="font-size: x-small;">Compared to the other studies, the incidence of nurses’ medication errors was somewhat higher in this study; however, the report rate was low. It is suggested that, by periodic measuring of job satisfaction and identifying factors that have impact on job satisfaction of nurses and also using strategies to resolve existing problems and dissatisfactions.</span>
Job satisfaction,Medication error,Nursing,Pediatric
https://ijp.mums.ac.ir/article_13355.html
https://ijp.mums.ac.ir/article_13355_70a02d82eaa8c91984eb1ea5248ff2b6.pdf
Mashhad University of Medical Sciences
International Journal of Pediatrics
2345-5047
2345-5055
7
9
2019
09
01
Aromatherapy with Iranian Herbal Medicines for Premenstrual Syndrome and Primary Dysmenorrhea: A Systematic Review and Meta-Analysis
10155
10166
EN
Mona
Najaf Najafi
0000-0003-4962-6787
Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Farnaz
Hadavi
0000-0002-1161-7626
Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
hadavif951@mums.ac.ir
Shima
Vazirinasab Kermani
Department of Obstetrics and Gynecology, Kerman University of Medical Sciences, Kerman, Iran.
Fahime
Vafisani
MSc of Nutrition, Medicine Faculty, Mashhad University of Medical Sciences, Mashhad, Iran.
Masumeh
Ghazanfarpour
0000-0003-4639-3711
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
masumeh.ghazanfarpour@yahoo.com
10.22038/ijp.2019.42455.3563
<span style="font-size: x-small;"><strong><em>Background</em></strong>: Primary dysmenorrhea is painful bleeding in the absence of any confirmed pelvic disorder, which is often accompanied by nausea, vomiting, and headache. The tendency of patients to use herbal and alternative medicine is more than the past. Regarding the fact that no meta-analytical study has been done to evaluate aromatherapy with Iranian herbal medicines, this study was conducted to evaluate the effect of aromatherapy with different herbs on premenstrual syndrome andprimary dysmenorrhea.</span><br /> <span style="font-size: x-small;"><strong><em>Materials and Methods: </em></strong>English and Persian electronic databases were systematically searched without any time limit until May 5, 2019. The references of review articles and clinical trials were also reviewed. Two authors independently reviewed the titles and abstracts, if the subject of the article was relevant, the full article was extracted and criticized. Comprehensive Meta-Analysis software was used to conduct meta-analysis. </span><br /> <span style="font-size: x-small;"><strong><em>Results: </em></strong>Finally, 14 studies were entered into a meta-analysis. The mean standard difference between two groups of aromatherapy with different plants and control group was -1.06 (95%CI: -1.33 to -0.848; p<0.001). Aromatherapy with roses (SMD=-1.35; 95%CI= -0.01 to -2.69; p=0.048), and aromatherapy with lavender (SMD= -1.08; 95% CI: -0.73 to -1.43; p<0.001) compared to the control group had better effect in reduction of pain severity. According to three studies, aromatherapy with Geranium 2% essential oil, Citrus aurantium blossom essential oil, and Rosa damascena were more effective than control group regarding mental and physical signs.</span><br /> <span style="font-size: x-small;"><strong><em>Conclusion</em></strong></span><br /> <span style="font-size: x-small;">This meta-analysis showed that aromatherapy with different Iranian herbs such as lavender and rose could significantly reduce primary dysmenorrhea and premenstrual syndrome. This treatment can be used specifically in patients who cannot tolerate conventional treatments.</span>
Aromatherapy,Dysmenorrhea,Herbal medicines,Iran,Premenstrual Syndrome
https://ijp.mums.ac.ir/article_13683.html
https://ijp.mums.ac.ir/article_13683_a8ed4f2c8b5e96262760508600e117a4.pdf