TY - JOUR ID - 8264 TI - Hair Shaft Abnormality in Children: a Narrative Review JO - International Journal of Pediatrics JA - IJP LA - en SN - 2345-5047 AU - Rahmatpour Rokni, Ghasem AU - Laali, Abolghasem AD - Assistant Professor, Dermatology Department of Mazandaran University of Medical Sciences, Sari, IR Iran. AD - Emergency Medicine, Mazandaran University of Medical Sciences, Sari, IR Iran. Y1 - 2017 PY - 2017 VL - 5 IS - 8 SP - 5451 EP - 5461 KW - Abnormality KW - Hair loss KW - Hair fragility KW - Hair shaft DO - 10.22038/ijp.2017.21803.1823 N2 - Background Hair is an ectodermal structure, and its formation is regulated by master genes important in embryology. Hair shaft consists of three major regions: the medulla, cortex and cuticle. Hair shaft abnormality will divide structural hair abnormalities into two broad categories - those associated with increased hair fragility and those not associated with increased hair fragility. We conducted a review study to assess hair shaft abnormality in children. Materials and Methods We conducted a review of all papers published on hair shaft abnormalities. A literature search was performed using PubMed, Scopus and Google Scholar on papers publish from 1990 to 2016. The search terms were: hair shaft abnormality, Hair loss, Hair fragility. All abstracts and full text English-language articles were studied. Results While common developmental and structural features are shared in hair follicles and hair shafts. Anomalies of the hair shaft are separated into those with and those without increased hair fragility. Conclusion Although hair has no vital function, it may serve as an indicator for human health. Clinical and morphological hair abnormalities can be clues to specific complex disorders. Hair shaft abnormalities can be inherited or acquired, can reflect a local problem or a systemic disease. UR - https://ijp.mums.ac.ir/article_8264.html L1 - https://ijp.mums.ac.ir/article_8264_51d5f90491f549034426b693319b8a1a.pdf ER -