TY - JOUR ID - 8816 TI - Quality Of Life in Children with Celiac Disease: A Cross-sectional Study JO - International Journal of Pediatrics JA - IJP LA - en SN - 2345-5047 AU - Jafari, Seyed Ali AU - Talebi, Saeedeh AU - Mostafavi, Nazanin AU - Moharreri, Fatemeh AU - Kianifar, Hamidreza AD - Department of Pediatric Gastroenterology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran AD - Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. AD - Department of Psychiatry, Ibn-e-Sina Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. AD - Department of Pediatric Gastroenterology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. Y1 - 2017 PY - 2017 VL - 5 IS - 7 SP - 5339 EP - 5349 KW - Anxiety KW - Celiac disease KW - Children KW - Depression KW - Gluten free diet DO - 10.22038/ijp.2017.23860.2017 N2 - Background Celiac disease (CD) is a systemic autoimmune disorder due to immune response triggered by ingestion of gluten in the diet. Treatment with lifelong gluten-free diet may impact negatively on the health-related quality of life and may lead to psychological disturbances. The purpose of study was to evaluate quality of life, depression and anxiety in children with celiac disease. Materials and Methods In this cross-sectional study was done between 2013 and 2014 at the Gastroenterology Outpatient Clinic (Ghaem Hospital, Mashhad- Iran), patients with serology and biopsy-proven CD, on a gluten-free diet for at least one year, were included in this study and compared with non-celiac healthy children as controls. We used the questionnaire to investigate quality of life, anxiety and depression. Results There were statistically significant differences between the mean total anxiety (state, trait) scores and depression score in the celiac patients and control group. Correlations between state and trait anxiety and depression were statistically significant (P= 0.01, r= 0.35) and (P= 0.001, r= 0.52). Reverse correlations between quality of life of CD children and anxiety (state, trait) were statistically significant (P= 0.001, r= 0.51 and P= 0.02, r= 0.32). Mean total score of quality of life was not different in the two groups, but in the physical activity component, quality of life was better in CD patients (P=0.008). Conclusion In current study, anxiety and depression had a significant impact on the course of celiac disease. UR - https://ijp.mums.ac.ir/article_8816.html L1 - https://ijp.mums.ac.ir/article_8816_b98f14dfacab471afe0952311ffbb467.pdf ER -