Assistant Professor, Department of Pediatrics, Behbahan School of Medicine, Behbahan, Iran.
Associated Professor, Neonatal Health Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Anesthesiology, Alborz University Of Medical Sciences, Alborz, Iran.
Nursing Care Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Pregnant women and newborns are at risk of vitamin D deficiency. This study aimed to determine the vitamin D status in pregnant women andtheir newborns in Karaj, Iran.
Materials and Methods
This cross-sectional study was conducted from March 2014 to October 2015. A total of 151 pregnant women and 154 newborns (three twin cases) were included in the study. After obtaining 5 ml venous blood samples from mothers and 5 ml blood from the umbilical cord of newborns, 25-hydroxy vitamin D [25(OH)D] was measured by ELISA method. Serum level of 25(OH)D below 20 ng/ml was considered deficiency, 21-29 ng/ml was considered insufficient and 30-100 ng/ml was considered sufficient. Data were analyzed using SPSS software version 20.0.
The prevalence of vitamin D deficiency and its insufficiency was 93.5% and 6.5% for pregnant women, 94.2% and 3.9% for newborns, respectively. The mean 25(OH)D concentration in pregnant women and newborns was estimated to be 10.649±5.967 ng/ml and 10.574±6.280 ng/ml, respectively. There was a significant correlation between the mean 25(OH)D concentration in mothers and their newborns (r=0.913 and p<0.001); 92.9% of mothers and their newborns had vitamin D deficiency simultaneously.
The results of this study showed that overall prevalence of vitamin D deficiencies (levels