PhD Student in Nursing, Student Research Committee, Faculty of Nursing and Midwifery, Semnan University of Medical Sciences, Semnan, Iran.
Faculty of Nursing and Midwifery, Nursing Care Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Department of Internal Medicine,Faculty of Medicine ,North Khorasan University of Medical Sciences, Bojnurd, Iran.
Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
The papers included in this study were published in 2000-2017. Of the included studies, 15 studies (22.38%) had been performed in Iran, and 26 studies (38.8%) were interdisciplinary. QoL in 24 studies (46.15%) had been evaluated using the SF-36. The terms QoL, HRQoL, and QL were used interchangeably in most of the studies. In this concept analysis, HRQoL and well-being were recognized as surrogate terms for the QoL in patients with thalassemia major. The concepts related to the QoL in patients with thalassemia major included satisfaction, indicator of health care, individual’s own view of health, and health status assessment. Five antecedents identified in this concept analysis were as follows: Professional ﬁgure mainly involved, clinical-care interventions, medicinal and therapeutic approaches and response to them, disease characteristics and presence of comorbidities, ability and characteristics of patient. Seven attributes of the QoL in patients with thalassemia major were as follows: objective, subjective, multidimensional, measurable, dynamic, predictable, and processable. Consequences of the concept were as follows: Effects on physical functioning and improvement of psychological conditions, compliance with regular chelation therapy, iron overload, continuing education, having an appropriate job and marriage, patients’ economic and social status, and ultimately motivation and life expectancy.