The Effect of Lavender for relief Painful Producer in Children and Infants: A Systematic Review


1 Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

3 Department of Anesthesiology, Mashhad University of medical sciences, Mashhad, Iran.

4 Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

5 Department of Nursing and Midwifery, Razi School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran.


Objective: To avoid these negative outcomes, the pain of the infants required to be precisely and thoroughly assessed, and the negative effects of the pain be lessened through the effective pain-relieving methods. Aim of this study is to give a comprehensive information about the effect of lavender for aliavative painful producer in infants and children.

Material and methods:
A systematic search was conducted on English databases of Scopus, PubMed, Cochrane Library, EMBASE and ISI Web of Science from inception to February 10, 2019. Authors performed search without any time restrictions. Two authors independently performed search and assess their quality.

The five studies were included into systematic review. In the first study, the change of NIPS score were significantly lower in lavender than control groups. The duration of crying was 75.47 (60.675) and 105.22 (75.739) seconds in the lavender and the control groups, respectively, which was significantly different. In second study, aromatherapy with lavender was unable to change the VAS score (p=0.40), while heart rate decreased to a significance borderline level (p=0.0639). In the third study, a significant differences in the mean SpO2 (p=0.003), respiratory rate (p=0.001), and heart rate (p=0.001) at different time points between the aromatherapy with lavender and the control groups in preschool children. In the fourth study, the lavender group exhibited lower NIPS score compared to the amniotic fluid and breast milk groups. In fifth study, 80 term infants were assigned into case (n=40), and control (n=40) groups. According to Mann-Whitney test analysis, there was a significant difference in pain scores between the two groups lavender and control (p=0.001).