Evaluation of QRS, QTC, JTC intervals in congenital heart disease with pulmonary hypertension


1 Assistant professor of Pediatrics Cardiology, Department Of Pediatrics, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran

2 Medical student, Department Of Pediatrics, Hamadan University of Medical Science, Hamadan, Iran.

3 Associate professor of Cardiology, Farshchian Heart Center, Hamadan University of Medical Science, Hamadan, Iran

4 Associate Professor of community medicine, Department of community medicine, Hamadan University of Medical Sciences, Hamadan, Iran.


Introduction: one of the most important group of congenital heart disease (CHD) that causes right to left shunt due to pulmonary hypertension (PH). Some studies reported QT interval prolongation in pulmonary hypertension in which can exaggerated the risk of life threatening arrhythmia.
Method: In this cross sectional study that was performed in pediatric cardiology clinic of Besat hospital using physical examination, echocardiography estimation and catheterization report patients with congenital heart disease and pulmonary hypertension recognized between 2016 and 2018 consecutively as case group. We selected consequently patients with simple CHD without any evidence of PH as control group .Based on mean PA to systemic ratio lower than 1/2 considered mild PH and equal and more than 1/2 considered severe PH and then compared in term of QRS, QTC, JTC intervals in ECG and RVMPI, TAPSE in echocardiography.
Results: In this study 40 patients in the case group compared with 40 patients in the control group. There was significant difference in QRS (p=0.005) and QTC (p=0.036) intervals but there wasn’t significant difference between JTC interval between two main group (0.714). Of 40 patients with PH, 19 subjects were in the mild PH group and 21 subjects were in severe PH group, in which 9 patients had irreversible PH or Eisenmenger syndrome. QTC (p