Assistant Professor, Department of Obstetrics and Gynecology, Neonatal and Maternal Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Obstetrics and Gynecology, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Assistant Professor of Pediatrics, Department of Pediatrics, Faculty of Medicine, Mashhad university of Medical Sciences, Mashhad, Iran.
Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Students Research Committee, Razi School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran.
Fellowship of Intensive Care Medicine, Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran.
MSN Geriatric of Nursing, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Guillain-Barre syndrome is a neurological disorder that begins with weakness of the limbs and can cause respiratory and cardiac involvement. The subject of this report is a 30-year-old woman who was diagnosed with Cushing’s syndrome following recurrent bone fractures and receiving treatment for the Cushing’s syndrome. The patient was referred to a hospital during pregnancy because of generalized pain and weakness in the extremities. Abdominal ultrasound showed a mass in the left adrenal gland and so surgery was performed to remove the mass.
However, the patient's symptoms did not improve after surgery. The patient was asked to consult a neurologist who made a diagnosis of Guillain-Barre syndrome after cerebrospinal fluid was examined. Patient was discharged with personal consent. Four months later, the baby was born with a normal Apgar score, and the general condition of mother and child were evaluated as good. This case demonstrates a rare coincidence of Cushing's disease and Guillain-Barre syndrome. Due to the increase in corticosteroids due to Cushing's syndrome, it is expected that symptoms of Guillain-Barre syndrome would not occur. This case could indicate that there are several mechanisms for development of Guillain-Barre syndrome and that animal models can be helpful in this context.