The impact of gestational diabetes mellitus on motor development in 12-month-old children attending to Qazvin University of Medical Sciences, Iran

Authors

1 PhD in Pediatric Neurorehabilitation, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 PhD in Reproductive Health, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

Introduction: The development of the brain during fetal period affects the functioning of the nervous system whole of the life. Numerous maternal disorders during pregnancy can affect fetal neural development, one of which is gestational diabetes. Gestational diabetes can have a long-term negative impact on the fetal neural development. The purpose of this study was to investigate the effect of gestational diabetes on motor development of 12-month-old children referred to Qazvin University of Medical Sciences.
Methods and Materials: In this prospective cohort study, 439 pregnant mothers referred to Qazvin University of Medical Sciences who met the inclusion criteria were sampled at 24-28 weeks of gestation. Then these women were followed up until child birth and after birth until 12 months afterwards. The process of motor development of their children at the age of 12 months was studied using the Age and Stage Questionnaire.
Result: The results of this study showed that among the women who participated in the study, 87 mothers had gestational diabetes. Of the 12-month-old children of the mothers who participated in this study, from 24 children with motor developmental delays, 11 children belonged to GDM mothers (87 women) whereas, the rest (11), were born from   the non-diabetic women (352 women).   The relative Risk of motor developmental delay in children born to mothers with gestational diabetes was 1.49 (95%, CI = 0.98-1.87).
Conclusion: The present study showed that gestational diabetes can be a powerful risk factor for child motor developmental delay (both fine and gross motor skills).

Keywords