University of California and San Francisco, Department of Epidemiology and Biostatistics, 1825 4th street, Mission Bay, San Francisco, CA 94154, USA.
State University of New York Medical University, Syracuse, NY 13202, USA.
SUNY Upstate Medical University
4Associate Professor of Pediatrics, ivision of Pediatric Gastroenterology, Hepatology, and Nutrition, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA.
Crohn’s disease is an inflammatory bowel disease (IBD), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. Environmental triggers and interaction of genetic determinants also play an indispensible role. In this case report, we present a pre-pubertal girl with intermittent and refractory genital swelling. We emphasize that Crohn’s disease must be considered in the differential diagnosis of recurrent, non-tender, erythematous and edematous lesions of the genital area. We conclude with future directions for diagnosing and managing vulvar Crohn’s disease in pediatric population.