Acute Disseminated Encephalomyelitis; A Rare Iranian Case Report

Authors

1 Medical Student, Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran

2 Student Research Committee, Shahrood University of Medical Sciences, Shahrood, Iran

3 Pediatric Resident, Golestan Pediatric and neonatal research center, Golestan University of Medical Sciences, Gorgan, Iran

4 Child and Adolescent Psychiatrist, Assistant, Professor of Psychiatry, Golestan Resaerch Center of Psychiatry, Golestan University of Medical Sciences, Gorgan, Iran

5 Medical Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran

6 Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Abstract

Acute disseminated encephalomyelitis (ADEM) is a monophasic clinical syndrome, characterized by immune-mediated demyelination of central nervous system neurons, which yield extensive damage in the brain and spinal cord.It usually affects children and young adults following infections or immunization.
Here we describe a 9- year-old Fars female presented with acute onset of psychotic disorder, one week after an upper respiratory infection. Magnetic resonance images (MRI) of the brain were consistent with the diagnosis of the acute disseminated encephalomyelitis (ADEM). ADEM is one of the differential diagnoses to be considered when an acute psychotic disorder arises during childhood especially as post vaccination or infection.

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