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80% of the malarial infections in the America. The artemisinins are very potent and fast-acting antimalarials, inducing more rapid parasite clearance and fever resolution than any other currently used of antimalarial drugs. They are particularly well suited for the treatment of severe Plasmodium falciparum malaria. The standard treatment of malaria infection employs artemisinin-based combination therapy. This antimalarial drug increases treatment efficacy and reduces selection pressure for the emergence of drug resistance. Artemisinins cause a significant reduction of the parasite burden, with a reduction in the parasite population. Only three to four cycles (6 to 8 days) of treatment are required to remove all parasites from the blood. Artemisinins are formulated for oral, intramuscular, intravenous, and rectal routs. Bioavailability after oral dosing is ≤ 30%. The aim of this study is to review the published data on the clinical pharmacology of artemisinins in children.]]>
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0.05). Conclusion The results of the study showed that prevalence of neonatal sepsis was 10.4% and the most common pathogenwas Escherichia coli. Lethargy, jaundice and respiratory distress, were the most common clinical features in neonatal sepsis.]]>
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0.05). In girls, there was no significant difference between type of delivery and hospitalization due to icterus (P=0.56). As the same in boys there was no significant difference between type of delivery and hospitalization due to icterus (P=0.059). Also, there was no difference in all neonates regardless of their sexuality, between type of delivery and hospitalization due to icterus (P=0.078). In cesarean delivery there was no significant difference in icterus severity between general and epidural anesthesia (P= 0.21). Conclusion The results indicate that cesarean delivery was not a risk factor for hospitalization due to icterus during first week after delivery. Further studies are recommended to confirm our results. ]]>
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