ORIGINAL_ARTICLE
Long-Term Survival of Peritoneal Dialysis in Children: A Cohort Study
Background: There is little information about the survival rate of pediatric peritoneal dialysis (PD) patients and its risk factors. Therefore, the aim of the present study was to assess survival rate and its risk factors in Iranian children undergoing PD. Materials and Methods: Demographic and laboratory data of 407 Iranian children (up to 19 years old) undergoing PD, from 20 centers in Iran were included. The outcome of interest in our study was survival rate and determination of its risk factors in PD children. The joint models of longitudinal and time-to-event data analysis was used. Results: The median duration of follow-up was 537 (interquartile range: 146 to 1,177) days. Finally, 72 (17.7%) patients died during a period of 23 years. Our results showed that one-year survival rate of PD patients was 93.6% and five-year survival rate was 76.9%. In addition, the most important risk factors for the PD all-cause mortality were age (HR=0.9301; 95% CI: 0.9031 to 0.9587), serum creatinine (HR=0.8907; 95% CI: 0.8138 to 0.9750), platelet count (HR=0.9999; 95% CI: 0.99995 to 0.99999), aspartate aminotransferase level (HR=1.0001; 95% CI: 0.9999, 1.0002), alkaline phosphatase (HR=0.9989; 95% CI: 0.9982 to 0.9997), renal solute clearance rate (HR=0.9839; 95% CI: 0.9700 to 0.9981), and normalized protein catabolic rate (HR=0.4031; 95% CI: 0.1879, 0.8648). Conclusion: The survival rate of Iranian pediatric PD patients is similar to other countries. It is suggested that laboratory assessment be continually
https://ijp.mums.ac.ir/article_13502_03823f4c3fd9d5d3b32a71432afed869.pdf
2019-09-01
10009
10017
10.22038/ijp.2019.41855.3525
Children, Mortality, Peritoneal Dialysis, Survival
Risk factors
Mahmoud
Yousefifard
yousefifard20@gmail.com
1
Prevention of Cardivascular Disease Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Neamatollah
Ataei
ataei_nm@yahoo.com
2
Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Department of Pediatric Nephrology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Shahin
Roshani
shahinroshani@ymail.com
3
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Fatemeh
Darabi
f.darabi@gmail.com
4
Department of Public Health, Asadabad School of Medical Sciences, Asadabad, Iran.
AUTHOR
Iraj
Najafi
najafi266@yahoo.com
5
Nephrology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Mojtaba
Fazel
mojtabafazel@yahoo.com
6
Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Department of Pediatric Nephrology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Zeynab
Talayi
talayiz@gmail.com
7
Pediatric Department, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Michael
Jones
michael.jones@icr.ac.uk
8
Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.
AUTHOR
Mehdi
Yaseri
m.yaseri@gmail.com
9
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Mostafa
Hosseini
mhossein110@yahoo.com
10
1- Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran. 2- Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Validity of Peripheral Capillary Oxygen Saturation and Normal Mixed Venous Oxygen Tension in Measurement of O2 Content
Background The change in venous oxygen saturation occurs earlier, and even its reduction is faster than arterial oxygen saturation. The aim of this study was to validate SvO2 and PvO2 for O2 content measurement in children hospitalized with respiratory distress. Materials and Methods In this cross-sectional study, 80 children who were admitted with respiratory distress were included in the study according to the study inclusion and exclusion criteria. Baseline characteristics such as age and gender were recorded in the data collection form, designed by the researcher. In order to determine the amount of SaO2 and PaO2 the arterial blood sample was prepared, venous blood sample was prepared to determine the amount of hemoglobin, SvO2 and PvO2. The gold standard for the determination of O2 content was the arterial blood sample. All samples were examined by a blood gas analyzer and then calculated using the formula of O2 content values. For SvO2 and PvO2 validation, we used diagnostic analysis methods including sensitivity, specificity, positive and negative predictive values. Cut-point value for SvO2 and PvO2 were 76.50 and 44.30, respectively. Results In this study, the patients’ mean age was 5.15 ± 4.20 years. 62.5% (n=50) were male and 38.5% (n=30) were female. The values of arterial and venous O2 content were 14.13 ± 3.05 and 11.95 ± 3.04 from a total of 80 patients. SvO2 and PvO2 for measuring O2 content had a sensitivity of 80.5 and 71.80%, respectively, and specificity of 80.5 and 78%, respectively. Conclusion SvO2 and PvO2 have good validity for evaluating O2 content in patients admitted to PICU. So that SvO2 had a sensitivity and specificity of over 80%, and PvO2 had a sensitivity and specificity of over 70%.
https://ijp.mums.ac.ir/article_13539_39543fba97bf88e1eb28f7173dd748a2.pdf
2019-09-01
10019
10027
10.22038/ijp.2019.41833.3522
Children
respiratory distress
SvO2
PvO2
Oxygen Content
Validity
Nemat
Bilan
bilannemat@yahoo.co.uk
1
Pediatric Pulmonologist, Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
LEAD_AUTHOR
Elnaz
Eskandartash
2
Fellowship of Pediatric Pulmonology, Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
ORIGINAL_ARTICLE
Evaluating the Short-Term Outcome of Mechanically Ventilated Neonates Admitted to the Neonatal Intensive Care Unit of Besat Hospital, Hamadan, Iran
Background Many neonates admitted to Neonatal Intensive Care Unit (NICU) need mechanical ventilation for recovery. This study was designed to evaluate the short-term outcome of mechanically ventilated neonates admitted to NICU. Materials and Methods In this descriptive cross-sectional study, all the neonates in need of mechanical ventilation in NICU of Besat Hospital, Hamadan, Iran, were enrolled for one year from September 2017 to September 2018. The selected data were of neonatal age at admission time, birth weight, gender, gestational age, indications of mechanical ventilation, lab results, length of hospital stay and the outcome of the disease were extracted from the medical file and analyzed using SPSS software (version 22.0). Results Of 141 mechanically ventilated neonates, 55.3% (n=78) were males. The mean of neonatal age, mean gestational age and mean birth weight were, 4.67 ± 6.58 days, 35.51 ± 3.88 weeks, and 2779.37 ± 827.06 g, respectively. RDS (58.9%) was the most common indication for mechanical ventilation. The overall rate of neonatal recovery was 51.8%. The results of unilabiate analysis showed a significant relationship between indications of mechanical ventilation, gestational age, neonatal birth weight, acidosis (pH <7.1), duration of mechanical ventilation, duration of hospitalization and the disease outcomes (P<0.05). Conclusion The results of this study showed that respiratory distress syndrome, low gestational age and birth weight, acidosis and duration of mechanical ventilation would lead to increased death in mechanically ventilated neonates.
https://ijp.mums.ac.ir/article_13501_134a9ed999b69d0c68b87ade76a7edb7.pdf
2019-09-01
10029
10034
10.22038/ijp.2019.41629.3507
outcomes
Mechanical Ventilation
neonate
Neonatal Intensive Care Unit
Amir Reza
Monsef
monsef_a@yahoo.com
1
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
AUTHOR
Fatemeh
Eghbalian
eghbalian_fa@yahoo.com
2
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
AUTHOR
Mohammad Kazem
Sabzehei
mk_sabzehei@yahoo.com
3
Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran.
LEAD_AUTHOR
Elham
Khanlarzade
khanlarzadeh@yahoo.com
4
Department of Community Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
AUTHOR
ORIGINAL_ARTICLE
Evaluation of Serum Levels of Calprotectin in Asthmatic Children
Background Calprotectin is a cytosolic protein that belongs to the S-100 protein group with immunomodulatory and antiproliferative actions. The level of this protein increases in infection, inflammation, and malignancy. The aim of this study was to evaluate the level of calprotectin in asthmatic children as indicator of asthma severity. Materials and Methods This is a prospective study that included forty-five children with bronchial asthma and admitted to pediatric department, Minia University Children’s Hospital, Egypt, they were (15 intermittent asthma, 15 mild persistent asthma and 15 moderate persistent asthma), and 20 apparently healthy children were included in the study and subjected to thorough history taking, full clinical examination, lung function test, CBC, Immunoglobulin E and measurement of serum levels of calprotectin using ELISA. Results The study revealed a statistically significant increase in the level of calprotectin in asthmatic children compared to that of the control group (p<0.000). Also, there was a significant increased level of calprotectin in children with persistent asthma compared to those with mild intermittent asthma and control group (p<0.001). In addition, there was a positive correlation between serum level of calprotectin and eosinophil count (r=0.83, p=0.001), and negative correlation with lung functions (FEV1 and PEEF) (r=-0.89 and r=- 0.88, respectively, p<0.05). Conclusion Increased levels of calprotectin in asthmatic children suggest that it may play a role in asthma, also it was associated with poor lung functions suggesting that there is a close relation between calprotectin level and the severity of childhood asthma.
https://ijp.mums.ac.ir/article_13457_fd30ec4b5ade93d3c2c3fbf54eaff2d1.pdf
2019-09-01
10035
10041
10.22038/ijp.2019.41484.3498
Asthma
calprotectin
Children
Immunoglobulin E
Pulmonary functions tests
Abdelhakeem
Abdel Mohsen
aboueyad1@yahoo.com
1
Associate Professor of Pediatrics, Departments of Pediatrics, El-Minia University, Mina, Egypt.
LEAD_AUTHOR
Ahmed
Abdelfadel
ahmedabdelfadeel@yahoo.com
2
Associate Professor of Clinical Pathology, Department of Clinical Pathology, El-Minia University, Mina, Egypt.
AUTHOR
ORIGINAL_ARTICLE
Prevention Strategies and Guidelines to Manage Obesity in Children and Young People
Obesity in children and young people is a significant public health issue. It can be associated with adverse health, economic and social implications. It is argued that preventing obesity needs adaptation to a healthy lifestyle, which includes behavioral modification, reduction in sedentary behavior, changes in nutrition, managing stress and increased physical activity. Families, healthcare professionals, school nurses, policy makers, researchers, and the community share responsibilities to prevent and manage obesity in children and young people.
https://ijp.mums.ac.ir/article_13458_aaf40a329abf47f47d723a75565d7d3e.pdf
2019-09-01
10043
10047
10.22038/ijp.2019.40813.3447
Children
Obesity
recommendations
young people
Khetam
Al-Awamreh
al-awamreh.k@aabu.edu.jo
1
Assistant Professor, Department of Maternal and Child Health Nursing, Princess Salma Faculty of Nursing, AL al-Bayt University, P.O. Box 130040, Mafraq, 25113, Jordan.
AUTHOR
Abdullah
Alkhawaldeh
dr-abd@jpu.edu.jo
2
Associate Professor, Faculty of Nursing, Jerash University, Amman - Irbid International Street 26150 Jerash, Jordan.
LEAD_AUTHOR
Sami
Aloush
sma91@case.edu
3
Assistant Professor, Princess Salma Faculty of Nursing/Al Al-Bayt University, Adult Healthcare Nursing Department, P.O. Box130040, Mafraq, 25113, Jordan.
AUTHOR
Intima
Alrimawi
intimarimawi@yahoo.co.uk
4
PhD, MSN, MPH, BSN (RN), Associate Nursing Program Director, Stratford University, USA.
AUTHOR
Mohammad
Al Qadire
mohammadqadire@abbu.edu.jo
5
Assistant Dean for Students Affairs, Head of Adult Healthcare Nursing Department, Princess of Salma Faculty of Nursing, Al Al-Bayt University, P.O. Box 130040 Mafraq 25113, Jordan.
AUTHOR
Mohammad
Suliman
mbarahemah@aabu.edu.jo
6
Associate Professor, Princess Salma Faculty of Nursing, Community and Mental Health Department, Al Al-Bayt University, Mafraq, Jordan.
AUTHOR
Manar
Al-Azzam
manar-alazzam@uiowa.edu
7
Associate Professor, Al-Albayt University/Princess Salma Faculty of Nursing, Mafraq, Jordan.
AUTHOR
Omar
Khraisat
khraisat1111@hotmail.com
8
Assistant Professor, Faculty of Nursing, Jerash University, Jordan, P.O. Box 26150 Jerash, Jordan.
AUTHOR
Moawiah
Khatatbeh
moawia.m@yu.edu.jo
9
Associate Professor of Public Health, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
AUTHOR
Mohammed
ALBashtawy
mohammadbash@aabu.edu.jo
10
Full Professor, Community and Mental Health Department, Princess Salma Faculty of Nursing, AL al-Bayt University, Jordan.
AUTHOR
ORIGINAL_ARTICLE
Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran
Background There are contradictory results regarding association between maternal HIV infection and neonatal adverse outcomes. Therefore, in this study the neonates born from HIV-positive mothers compared with HIV-negative mothers were assessed in Tehran, Iran. Materials and Methods This retrospective case-control study was conducted on 50 infants born to an HIV-positive mother compared with 53 infants born to an HIV-negative mother as control group, during 8 years of a period from 2006-2015, admitted in Valiasr Hospital of Tehran. Data were gathered from medical records of patients. Results All children (n=53, 100%) in the case group were born through cesarean section; while 20.75% of the control group children were born by natural delivery (P=0.001). There was statistically significant difference between neonates born from HIV-positive mothers compared to HIV-negative mothers with respect to delivery method and gender (P<0.05). The mean weights (gr) were higher in the controls than the cases (3052.830±380.71 vs. 2731.80±575.90) (P=0.001). Also, a significantly increased Hemoglobin was observed in the controls (15.87±1.97 g/dL) compared to the cases (13.42±1.69 g/dL) (P=0.001). Liver functions test (LFTs)was significantly higher in case groups (P=0.005). Conclusion Based on the results,the mean weight and hemoglobin were lower in infants born from HIV-positive women compared with HIV-negative women. Also, LFT Disorder was higher in infants born from HIV-positive women compared with HIV-negative women.
https://ijp.mums.ac.ir/article_13208_4cfc62222b045bcaca1b0cd32ef07b69.pdf
2019-09-01
10049
10056
10.22038/ijp.2019.40474.3422
Aids
Infant
HIV
Mother
Nahid
Najafi
nahid.najafii1987@gmail.com
1
Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Elahe
Amini
s_khazaeii@yahoo.com
2
NICU Division, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Khadije
Daneshjou
daneshjou1981@gmail.com
3
Department of Pediatrics, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Hossein
Pesarakli
pesarakli.h@yahoo.com
4
Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Mahnaz
Akbari
mahnaz1330@yahoo.com
5
Department of Pediatrics, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
AUTHOR
ORIGINAL_ARTICLE
Evaluation of Electrocardiographic Parameters in Diabetes Mellitus Type I in Children and Adolescent
Background Cardiovascular complications are continuing to be a major cause of morbidity and mortality in diabetes mellitus type I (DMTI). The study aimed to evaluate the rate of changes in ECG parameters in children with DMTI compared with healthy children. Materials and Methods This case-control study was performed on 140 participants which consisted of 70 patients with DMTI (case group) matched in sex and age with 70 healthy ones (control group) in two centers in collaboration with Ali Asghar Hospital, Zahedan, Iran, between March 2017 and April 2018. Electrocardiography was performed in all participants (patients and healthy), and heart rate, QT (start of the Q wave and the end of the T wave) QTc interval (QT/√ RR), QTd (dispersion between maximum and minimum of QT), and QTcd (dispersion between maximum and minimum of QTc) were measured. Duration of diabetic and level of HbA1c were obtained for patients and the effects of these parameters on ECGs were investigated. Results Height, weight and heart rate were higher in the patients (P<0.001) when S in V1 was higher in case (6.16±3.23) compared to the control group (4.33± 2.22) (P<0.001). QT (356.71±27.28 compared to 347.00±23.55), QTd (49.00±14.66 compared to 41.21±8.32), and QTcd (60.47±17.32 compared to 49.93±10.44) were higher in case group (p<0.05). Hemoglobin A1C (p=0.043) was higher in boys and heart rate was higher in girls (p<0.001). Diabetic time duration and HbA1c normality states did not change the length of these parameters in diabetic patients. Conclusion Based on the results, QT, QTd, QTc and QTcd were higher in patients with DMTI. Diabetic time duration and HbA1c states did not change the ECG parameters in diabetic patients.
https://ijp.mums.ac.ir/article_13219_c11b725748bb458669ca75c162e3f64f.pdf
2019-09-01
10057
10066
10.22038/ijp.2019.40337.3417
Adolescents
Children
Diabetes Mellitus
QT changes
Noor Mohammad
Noori
dr_noori_cardio@yahoo.com
1
Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
AUTHOR
Alireza
Teimouri
alirezateimouri260@gmail.com
2
Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
AUTHOR
Maryam
Nakhaee Moghadam
maryamnakhaey@yahoo.com
3
Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
LEAD_AUTHOR
Maryam
Kasravi
dr_maryam_kasravi67@yahoo.com
4
School of Medicine, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.
AUTHOR
ORIGINAL_ARTICLE
Factors Affecting Child Labor in Iran: A Systematic Review
Background For decades, child labor has been an important global issue associated with inadequate educational opportunities, poverty and gender inequality. In order to make effective policies to reduce child labor it is important to understand the specific factors that affect it. We aimed to investigate the main factors affecting child labor n Iran. Materials and Methods There are authoritative websites on the topic of working children in Iran, including the WHO, UNFPA, UNDP, Web of Science, ProQuest, Medline, Scopus, and CINAHL databases for reviewing studies conducted in Iran. Articles from internal dissertations and Google's databases, SID, Magiran, and Iran Doc during the period 1985 to June 2019 were included. Quality of studies was reviewed by the STROBE checklist. Information was extracted by two blind researchers. Results A total of 9 studies were identified (including 17, 219 on child labor), the majority of which were cross-sectional. Affecting factors on child labor and Street children were grouped into four categories such as "Family problems", "Urbanization", "Social and Cultural", and "Personality". Conclusion In the contemporary Iranian society, many children, for some reasons including personal, family, social and cultural, and urbanization problems, are involved with important social damages such a child labor. These factors make children vulnerable and endanger the health of the community.
https://ijp.mums.ac.ir/article_13451_f0678e429a884fcec7b3a830cd1c0774.pdf
2019-09-01
10067
10075
10.22038/ijp.2019.41689.3510
Children
labor
Iran
Systematic review
Sara
Ghahremani
1
Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Shahrzad
Khosravifar
2
Psychiatrist, Fellowship of Sleep Medicine, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Masumeh
Ghazanfarpour
masumeh.ghazanfarpour@yahoo.com
3
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
Zahra
Sahraei
4
Bahar Hospital, Shahroud University of Medical Science, Shahroud, Iran.
AUTHOR
Abdolhadi
Saeidi
5
Social Work, Lmam Khomeini Hospital of Mahabad, Urmia University Of Medical Sciences, Mahabad, Urmia, Iran.
AUTHOR
Hamed
Jafarpour
6
Student Research Committee. Faculty of medicine, Mazandaran University of Medical Sciences, Sari, Iran.
AUTHOR
Shaghayegh
Khosravifar
7
Resident of Psychiatry, Isfahan University of Medical Science, Isfahan, Iran.
AUTHOR
Firoozeh
Mirzaee
8
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
Masoudeh
Babakhanian
9
Social Determinants of Health Research Center, Semnan University Of Medical Sciences, Semnan, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Pathology of Cyberspace: A Study of the Detrimental Effects of Mobile Phones on Students' Psychological Well-being
Background In addition to their widespread applications in various fields, cellular phones have some inappropriate social consequences, including psychosocial addiction, degradation of values, reduced social interactions, early maturity and endangering the psychological well-being of users. Therefore, the present study aimed to investigate detrimental effects of Mobile phones on the psychological well-being of second grade students. Materials and Methods In this cross-sectional study, the sample population included 269 second grade students (107 boys and 162 girls) in Kermanshah, Iran in 2018 and being in the 10-18 age-range who were selected using cluster sampling. As for data collection, the Jenaro’s Cell-Phone Over-Use scale and Ryff’s psychological well-being scale were utilized, which were filled out by the students themselves. Results The results of the present study demonstrated that the means of the deleterious use of mobile phones and psychological well-being measured 44.71±16.45 (total score=126), and 63.86±14.43 (total score=84), respectively. The results also indicated that the observed F (F=10.12) was significant at p<0.005, and the predictor variables together explained 0.33 of the variance of psychological well-being. Moreover, it was shown that the deleterious use of mobile phones and psychological well-being significantly and negatively correlated at p<0.005, r=0.49. Conclusion According to this study, it was revealed that the deleterious overuse of mobile phones and psychological well-being were significantly and negatively correlated; which means that the higher the use of mobile phones, the more vulnerable the psychological well-being becomes.
https://ijp.mums.ac.ir/article_13123_1ae98ac5109b8e14b9e18a6e6f2c9c7b.pdf
2019-09-01
10077
10085
10.22038/ijp.2019.39704.3381
effects
Mobile Phone
Students
Well-Being
Marzieh
Kaboudi
f_kaboudi@kums.ac.ir
1
Department of Reproductive Health, Nursing and Midwifery Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran.
AUTHOR
Manoj
Sharma
manoj.sharma@jsums.edu
2
Behavioral and Environmental Health, School of Public Health, Jackson State University, Jackson, MS, USA.
AUTHOR
Arash
Ziapour
arashziapoor@gmail.com
3
PhD Student, Health Education and Health Promotion, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
AUTHOR
Fateme
Dehghan
fatemedehghan1368@gmail.com
4
Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
AUTHOR
Parvin
Abbasi
pabasi2003@yahoo.com
5
Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Medicinal Herbs Useful in Pediatric Fever from the Perspective of Persian Medicine
Background Fever is the most important and common symptom of pediatric diseases. Fever can be a sign or symptom or complication of disease. Considering the development of complementary and alternative medicine worldwide and the prevalence of this symptom in children, we aimed to investigate their application based on Persian medical textbooks by searching herbs used in pediatric fever. Materials and Methods In this review study, materials were extracted by searching in reliable Persian medical textbooks of the10th -20th century using related Persian medicine keywords. Then the documentations for herbs extracted were searched in the databases based on the conventional medicine. The interpretation was made based on the results. Results Based on the Persian medical textbooks, seventeen herbs have been prescribed for decreasing pediatric fever. Among them, 16herbs have proven mechanisms of action for treatment of fever, classified into five categories (diaphoretic, anti-inflammatory, anti-septic, immunomodulatory, anti-oxidant) based on literature review. On the other hand, according to Persian medicine, there were thirteen cold temperament herbs and only four hot temperament ones. They were administrated using various oral and topical methods. The maternal and neonatal treatment was emphasized. Conclusion According to this study and documentations of conventional medicine, many of these herbs can be effective in the treatment of pediatric fever, so further clinical studies are recommended for evaluating their efficacy.
https://ijp.mums.ac.ir/article_13525_2fbd3a3774f015f05ee325fe55cb2c11.pdf
2019-09-01
10087
10098
10.22038/ijp.2019.41502.3500
Fever
Herbal Medicine
Pediatric
Persian Medicine
Medicinal Plants
Fatemeh
Hadian
f.hadian1985@gmail.com
1
Department of Traditional Medicine, Faculty of Traditional Medicine, Tabriz University of Medical Science, Tabriz, Iran.
AUTHOR
Mojtaba
Varshochi
varshochimo@gmail.com
2
Professor, Infectious and Tropical Disease Research Center, Tabriz University of Medical Science, Tabriz, Iran.
LEAD_AUTHOR
zohre
Feyzabadi
feyzabadi_8823@yahoo.com
3
School of Persian and Complementary Medicine, Mashhad University of Medical Science, Mashhad, Iran.
AUTHOR
Arman
Zargaran
zargarana@sums.ac.ir
4
Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Mehdi
Besharat
besharatsearch@yahoo.com
5
Department of Infectious Disease, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Mojtaba
Mousavi Bazaz
mousavim@mums.ac.ir
6
Department of community Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
AUTHOR
ORIGINAL_ARTICLE
Acute Hepatorenal Dose Dependent Toxicity of Teucrium Polium Hydro Alcoholic Extract in Rat
Background Based on vast usage of teucrium polium (TP) in alternative medicine of developing countries for treatment of ailments in children and adults, this study is designed to examine acute hydro alcoholic extract of TP effects in different doses on rat liver and kidney functions and tissue structures. Materials and Methods Animals were given daily intraperitoneal (i.p.) injection of TP at 3, 10, 30, 100, and 200 mg/kg or equal volume of normal saline for a week. One-hour postprandial blood glucose at day 1 and day 7, liver enzymes, serum creatinine (Cr), blood urea nitrogen (BUN) and hepatorenal tissues were examined at the end of the study. Animal body weights were also measured on a daily basis. Results TP at 3, 10, 30 and 100 mg/kg body weight didnot affect functional and structural characteristics in rat liver and kidney tissues compared with control animals. However, at high 200 mg/kg dose, it provoked liver and kidney tissue damages together with significant rise in aspartate aminotransferase (p<0.001), alanine aminotransferase (p=0.001), Cr (p=0.001), and BUN (p=0.001). Animal body weight in each group under TP pretreatment protocol unchanged during the study except at high 200 mg/kg which showed a significant weight loss (p<0.001). Conclusion TP detrimental health effects especially on liver and kidney tissues are frequently overemphasized, but in adose-dependent manner. However, we also believe TP has potential medical benefits and can find a way to the medical arena if thorough conducted researches can determine its toxic components and isolate appropriate derivatives for ensuing use.
https://ijp.mums.ac.ir/article_13340_5ac56d2f7d0f8fb7462275a56ba0d841.pdf
2019-09-01
10099
10107
10.22038/ijp.2019.41222.3475
Iranian Traditional Medicine
liver toxicity
kidney toxicity
Teucrium polium
Tayyeb
Ghasemi
scince.tgb@gmail.com
1
Basic Electrophysiology Research Centre, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Mansoor
Keshavarz
keshavarzm@tums.ac.ir
2
Basic Electrophysiology Research Centre, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Mohsen
Parviz
mohsenparviz110@gmail.com
3
Basic Electrophysiology Research Centre, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran AND Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Efficacy of Cold Therapy and Passive Stretching to Improve Gait in Spastic Diplegic Cerebral Palsy Children
Background One of the most common causes of severe physical disability in childhood is cerebral palsy (CP). Mobility is one of the most important functions to fulfill the activities of daily living. We aimed to determine the effectiveness of cold application to improve the ambulation in spastic diplegic CP children. Materials and Methods In this clinical trial study, 40 subjects were included for the study. They were divided into two groups, namely experimental (n=20), and conventional group (n=20). Study was carried out in Holy Cross College, Department of Rehabilitation Science, Tiruchirappalli, India. Conventional group was given regular conventional training and experimental group was given cold therapy, passive stretching in both legs before training. Both groups received training for 45 minutes, 3 times a week for a duration of 6 weeks. Modified Ashworth scales were used to measure spasticity step length, stride length and Cadences were used to measure the gait parameters, and Timed Up and Go test (TUG) was used to measure the functional activity. Results Significant effect was observed in decrease in spasticity, there was increase in gait parameters and timed up and go test in two studied groups. The post-test mean values of all the variables of cold therapy, passive stretching in experimental group are improved compared with that of conventional group. The experiment improved with stride length, step length, cadence, timed up and go test and Modified Ashworth scale (p<0.05). Conclusion Based on the derived results, there was decreased tone in spastic muscles and improvement in gait parameters and functional ability in children with diplegic CP after application of cold therapy and passive stretching.
https://ijp.mums.ac.ir/article_13536_0deb201271eae889b824e406f248382c.pdf
2019-09-01
10109
10118
10.22038/ijp.2019.41071.3461
Children
Cold therapy
Diplegic Cerebral palsy
spasticity
Gait
Passive stretching
Chinnavan
Elanchezhian
elanchezhianrehab@gmail.com
1
Research Scholar, Department of Rehabilitation Science, Holy Cross College, India.
LEAD_AUTHOR
P
Swarnakumari
swarnaravichandran@gmail.com
2
Associate Professor, Department of Rehabilitation Science, Holy Cross College, India.
AUTHOR
ORIGINAL_ARTICLE
Gyrate Atrophy of the Choroid and Retina: A Case Report
Introduction Gyrate atrophy of the choroid and retina is a metabolic disorder, which is inherited in an autosomal recessive pattern. Although gyrate atrophy is rare, it is concerning as it results in blindness. It is characterized by hyperornithinemia, retinal atrophy, leads to progressive myopia and tunnel vision, and Posterior Subcapsular Cataracts. Patients have lower amounts of ornithine aminotransferase. Case Report In this study, we report a 17-year-old boy referred to our hospital by an ophthalmologist, with progressive visual loss from 7 years of age. The eye examinations manifested chorioretinal degeneration and high myopia. In lab data, plasma ornithine amount was elevated 10-fold higher than normal. By this finding, he was diagnosed as having Gyrate Atrophy. Conclusion Treatment with pyridoxine and low arginine diet can reduce the ornithine plasma level in Gyrate Atrophy. Our report is to describe the first case of gyrate atrophy in pediatric endocrinology department in Iran diagnosed by biochemistry and treated with pyridoxine and low arginine diet.
https://ijp.mums.ac.ir/article_12175_54952f00dbf750c20d61c53c82fe92aa.pdf
2019-09-01
10119
10123
10.22038/ijp.2019.36478.3179
Adolescent
Coronary artery aneurysm
Idiopathic aneurysm
Cardiac catheterization
Somayyeh
Hashemian
hashemians951@mums.ac.ir
1
Department of Pediatric Endocrinology and Metabolism, Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Rahim
Vakili
vakilir@mums.ac.ir
2
Department of Pediatric Endocrinology and Metabolism, Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran AND Medical Genetic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Azadeh
Zare Feizabadi
zarefa951@mums.ac.ir
3
Department of Pediatric Endocrinology and Metabolism, Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Advantages and Disadvantages of Methadone among Children and Adults: A Systematic Review and Meta-Analysis
Background: Today, an increasing trend to methadone as an alternative maintenance treatment for opiate dependence in adults is observed; children for both intentional and accidental reasons are exposed to serious and fetal effects of methadone. We aimed to investigate effects of methadone on children and sexual functioning among adults in Iranian population.Materials and Methods: An extensive search was done in databases of Medline, EMBASE, Scopus, Cochrane, and Web of Science until August 2018. Two independent researchers screened articles, and categorized them based on the evaluated outcomes and overall effect size was presented. After excluding the duplicated, irrelevant and low-quality articles, eligible ones were enrolled in the meta-analysis. Finally, pooled effect size was presented as standardized mean difference (SMD) or pooled prevalence with 95% confidence interval (95% CI). Results: Methadone was found to be more effective than morphine on neonatal abstinence syndrome. The first four most common symptoms of methadone poisoning were loss of consciousness (81%), sleepiness (72%), meiotic pupils (76%), vomiting (56%), and Apnea (48%). The overall prevalence rate of sexual disorders and erectile dysfunction was 66.3% and 77.5%, respectively. The subjects in methadone group were over 2.5-fold more likely to use condom during intercourse (p<0.001). The methadone therapy could lead to a significant reduction in orgasm functioning (p<0.001), and a significant improvement in libido (p=0.001). The methadone maintenance treatment (MMT) significantly resulted in decreased orgasm function and improved libido in males.Conclusion: Evidence suggests a positive impact of methadone maintenance treatment on risky sexual behaviors. Regarding the methadone poisoning effect on children, people should be informed by health care providers about serious and fetal effects on children.
https://ijp.mums.ac.ir/article_13507_9b927972316afe84fea90f45717c7858.pdf
2019-09-01
10125
10137
10.22038/ijp.2019.41697.3511
Children
Iran
methadone
Meta-analysis
Poisoning
Sexual functioning
Masoudeh
Babakhanian
1
Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran.
AUTHOR
Kaveh
Mousavi Kani
kavehmed@gmail.com
2
Head and Neck Research Center, Facial plastic surgery division, Tehran University of Medical Science, Tehran, Iran.
AUTHOR
Hoda
Shojaei
3
Pediatrician, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Robabeh
Mousavi nezhad
moosavinezhad_s@yahoo.com
4
Pediatrician, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Farida
Daneshvar Mozaffari
5
Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Kourosh
Sayehmiri
6
Psychosocial Injouries Research Center, Ilam University of Medical Sciences, Ilam, Iran.
AUTHOR
Shahrzad
Khosravifar
7
Psychiatrist, Fellowship of Sleep Medicine, Rasool Akram Hospital, Iran University of Medical Science, Tehran, Iran.
AUTHOR
Shaghayegh
Khosravifar
8
Resident of Psychiatry, Isfahan University of medical science. Isfahan, Iran.
AUTHOR
Abolfazl
Fattah
9
Semnan University of Medical Science, Semnan, Iran.
AUTHOR
Masumeh
Ghazanfarpour
masumeh.ghazanfarpour@yahoo.com
10
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
LEAD_AUTHOR
Firoozeh
Mirzaee
11
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
ORIGINAL_ARTICLE
The Relationship between Medication Errors with Job Satisfaction of Nurses in Pediatric Ward
Background Medication errors are known as a preventable cause of idiopathic damage in pediatrics. These errors could entail serious direct and indirect outcomes that often lead to disruptions in the health care system. The present study aimed to determine the relationship between medication errors with job satisfaction of nurses in pediatric ward. Materials and Methods This cross-sectional, descriptive-analytical study was conducted on 80 nurses working in pediatric wards in hospitals affiliated with Ahwaz University of Medical Sciences, Iran that were selected by census. The questionnaires of medication administration error and nurses' job satisfaction (Minnesota job satisfaction) by purposive sampling were used for gathering data. Validity and reliability were checked for internal consistency and stability. Results Mean nurses’ medication errors in pediatric wards for every nurse over a 3-month period was 11.41+ 11.79 cases, and mean error reporting was 1.97+ 3.92 cases. Nurse’s age (P≤0.01) and education level (P≤0.03) were statistically significantly related with medication errors. The findings of job satisfaction of nurses showed that 44.07% of nurses were dissatisfied. However, there was no significant relationship between incidence of medication errors and nurses’ job satisfaction (r= -0.167, P= 0.138). Conclusion Compared to the other studies, the incidence of nurses’ medication errors was somewhat higher in this study; however, the report rate was low. It is suggested that, by periodic measuring of job satisfaction and identifying factors that have impact on job satisfaction of nurses and also using strategies to resolve existing problems and dissatisfactions.
https://ijp.mums.ac.ir/article_13355_70a02d82eaa8c91984eb1ea5248ff2b6.pdf
2019-09-01
10141
10153
10.22038/ijp.2019.40926.3450
Job satisfaction
Medication error
Nursing
Pediatric
Fatemeh
Hajibabaee
hajibabaeefateme@yahoo.com
1
Assistant Professor, School of Nursing & Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Masoomeh
Salehi Kamboo
masoome_salehi@yahoo.com
2
MSc in Nursing, Nursing & Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
AUTHOR
Somayeh
Faghanipour
faghanipour@gmail.com
3
PhD Candidate of Nursing, School of Nursing, University of Toronto, Centre for Biomedical Ethics and Law, KU Leuven, Belgium.
AUTHOR
Hadis
Ashrafizadeh
ashrafizadeh.h1993@gmail.com
4
PhD Student of Nursing, Nursing and Midwifery School, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
LEAD_AUTHOR
Mohamad Hossein
Haghighi Zadeh
haghighizadeh@ajums.ac.ir
5
MSc in Statistics, Ahvaz Jundishapur University of Medical Sciences. Ahvaz, Iran.
AUTHOR
ORIGINAL_ARTICLE
Aromatherapy with Iranian Herbal Medicines for Premenstrual Syndrome and Primary Dysmenorrhea: A Systematic Review and Meta-Analysis
Background: Primary dysmenorrhea is painful bleeding in the absence of any confirmed pelvic disorder, which is often accompanied by nausea, vomiting, and headache. The tendency of patients to use herbal and alternative medicine is more than the past. Regarding the fact that no meta-analytical study has been done to evaluate aromatherapy with Iranian herbal medicines, this study was conducted to evaluate the effect of aromatherapy with different herbs on premenstrual syndrome andprimary dysmenorrhea. Materials and Methods: English and Persian electronic databases were systematically searched without any time limit until May 5, 2019. The references of review articles and clinical trials were also reviewed. Two authors independently reviewed the titles and abstracts, if the subject of the article was relevant, the full article was extracted and criticized. Comprehensive Meta-Analysis software was used to conduct meta-analysis. Results: Finally, 14 studies were entered into a meta-analysis. The mean standard difference between two groups of aromatherapy with different plants and control group was -1.06 (95%CI: -1.33 to -0.848; p<0.001). Aromatherapy with roses (SMD=-1.35; 95%CI= -0.01 to -2.69; p=0.048), and aromatherapy with lavender (SMD= -1.08; 95% CI: -0.73 to -1.43; p<0.001) compared to the control group had better effect in reduction of pain severity. According to three studies, aromatherapy with Geranium 2% essential oil, Citrus aurantium blossom essential oil, and Rosa damascena were more effective than control group regarding mental and physical signs. Conclusion This meta-analysis showed that aromatherapy with different Iranian herbs such as lavender and rose could significantly reduce primary dysmenorrhea and premenstrual syndrome. This treatment can be used specifically in patients who cannot tolerate conventional treatments.
https://ijp.mums.ac.ir/article_13683_a8ed4f2c8b5e96262760508600e117a4.pdf
2019-09-01
10155
10166
10.22038/ijp.2019.42455.3563
Aromatherapy
Dysmenorrhea
Herbal medicines
Iran
Premenstrual Syndrome
Mona
Najaf Najafi
1
Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Farnaz
Hadavi
hadavif951@mums.ac.ir
2
Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Shima
Vazirinasab Kermani
3
Department of Obstetrics and Gynecology, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
Fahime
Vafisani
4
MSc of Nutrition, Medicine Faculty, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Masumeh
Ghazanfarpour
masumeh.ghazanfarpour@yahoo.com
5
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
LEAD_AUTHOR