ORIGINAL_ARTICLE
COVID-19 Associated Thrombocytopenia in Children: An Emerging Issue
Thrombocytopenia is a risk factor for increased mortality and morbidity during the Coronavirus Disease 2019 (COVID-19). In patients with COVID-19, the mechanisms lead to thrombocytopenia seems to be multifactorial. Thrombotic consumption of platelets in microvasculature, cytokine release, sepsis, and drug induced, direct infection of megakaryocytes and autoimmune destruction of platelets are the leading etiologies in COVID-19 and thrombocytopenia. In this overview, the research was conducted by screening the relevant articles evaluating the COVID-19 associated thrombocytopenia in children. An electronic search was performed in online databases of Scopus, EMBASE, Cochrane, Web of Science and Medline (via PubMed) with English language from December 2019 up to September 2020. Thrombocytopenia at admission in patients with SARS-CoV-2 infection is common, but delayed phase thrombocytopenia (occurring 2 weeks after beginning of symptoms) is uncertain. The delayed phase thrombocytopenia in COVID-19 is more prevalent in infected case with low lymphocyte count at admission and has a significant correlation with higher mortality rate. In majority of cases with COVID-19 and thrombocytopenia, the platelet count is mildly decreased. Severe thrombocytopenia or a prompt decline in number of platelets often indicates immune mediated thrombocytopenia or in late terminal stages of this infection. Thrombocytopenia is a significant finding in patients with severe type of COVID -19. Immune mediated platelet destruction might account for the delayed-phase thrombocytopenia in a group of patients, and can manifest as severe thrombocytopenia. It is important for practitioners to be vigilant and aware of this hematologic abnormality.
https://ijp.mums.ac.ir/article_16744_69f495740440ec64d7900a2aa56ee131.pdf
2021-06-01
13635
13642
10.22038/ijp.2020.52364.4162
Children
COVID-19
Immune thrombocytopenia
SARS-CoV-2
Thrombocytopenia
Mozhgan
Hashemieh
mozhganhashemieh@gmail.com
1
Pediatric Hematologist and Oncologist, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Shahrzad
Tabatabaee
shahrzadtabatabai@gmail.com
2
Neonatologist, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Mitra
Radfar
mrad1@yahoo.com
3
Neonatologist, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Parnian
Fahim
parnianfahim@gmail.com
4
Guilan University of Medical Sciences, Rasht, Iran.
AUTHOR
ORIGINAL_ARTICLE
The Effect of Sildenafil on Intrauterine Growth Restriction (IUGR) of Fetus with Gestational Age above 28 Weeks and Neonatal Outcomes
Background Intrauterine growth restriction (IUGR) is one of the main causes of mortality and morbidities of the perinatal period. This study aimed to investigate the therapeutic effects of sildenafil on Intrauterine Growth Restriction (IUGR) of fetus. Materials and Methods: This study was a double-blinded clinical trial performed on 80 pregnant women with gestational age above 28 weeks and fetal weight below 10% percentile and AC below 3%. The patients were divided into two groups: the recipient of 25 mg of oral sildenafil daily (n=40) (made by Marham Darou in Tehran, Iran), and the group, receiving placebo (n=40). The two groups were evaluated weekly in terms of ultrasound factors such as fetal weight, AC, PI, and RI of the umbilical and cerebral arteries, and S / D of the umbilical artery. Results: The mean age of the patients was 30.86 ± 5.77 years. Regarding MCA.PI, UA.PI, S / D, MCA.R and UA.RI indices, it was observed that these indices improved significantly in the intervention group (P <0.05). In the intervention group, after receiving the drug, the mean number of days to delivery was 12.05 days, and in the control group, after receiving placebo was 10.00 days (P = 0.001). The mean birth weight and score of Apgar minutes 1 and 5 in the intervention group was significantly higher than the control group (P <0.05). Conclusion Sildenafil can improve MCA.PI, UA.PI, S / D, MCA.R and UA.RI indices. Sildenafil increase the mean birth weight and score of Apgar minutes 1 and 5. Additionally, hospitalization in the NICU after taking sildenafil is shortened.
https://ijp.mums.ac.ir/article_17544_ad9136652dd3e40b4c7091e22769b4b2.pdf
2021-06-01
13643
13651
10.22038/ijp.2021.48984.3928
fetus
Gestational Age
IUGR
neonate
Sildenafil
Nooshin
Eshraghi
eshraghinooshin@yahoo.com
1
Fellowship of Perinatal, Department of Obstetrics and Gynecology, Akbarabadi Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran AND Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Akbarabadi Teaching Hospital, Tehran, Iran.
AUTHOR
Mahdiss
Mohamadianamiri
2
Fellowship of Gyneconcology, Department of Obstetrics and Gynecology, Akbarabadi Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Maryam
Ebrahimi
3
Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Akbarabadi Teaching Hospital, Tehran, Iran.
AUTHOR
Fahimeh
Karimi
fahimehkarimi554@gmail.com
4
Department of Obstetrics and Gynecology, Iran University of Medical Sciences, Akbarabadi Teaching Hospital, Tehran, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Examining Prevalence of Fetal Defects and Related Factors in Neonates Born and Hospitalized in Kerman Reference Hospital: A 66-Month Study
Background: Congenital malformations are one of the most important causes of disability and mortality of neonates. Many of these defects can be prevented. Therefore, recognizing and preventing the threatening factors that cause the adverse outcomes of pregnancy can prevent excessive costs to the family and society. The present study was performed to determine the prevalence of congenital malformations and some related factors in Afzalipour Hospital in Kerman, Iran. Materials and Methods: In this cross-sectional study and historical cohort, 1089 neonatal files were selected from 43076 files in the period of March 2014 to September 2019 by stratified sampling method with proportional allocation. Maternal and neonatal information including gender of infant, maternal and neonatal blood type, first and fifth minute Apgar score, LMP-based gestational week, maternal underlying disease, history of disease in pregnancy, maternal addiction, maternal number of pregnancies, number of childbirths, number of live children, number of stillbirths, history of abortion and stillbirth, type of childbirth and the congenital anomalies and its type were extracted from the files and recorded in the researcher-made checklist. Results: The prevalence of congenital malformations in neonates was 16.6%. The most common malformations were cardiovascular malformations (55.3%) and genitourinary malformations (19.3%). Girl gender, lack of maternal addiction, increasing maternal pregnancy, low Apgar score, and hospitalization in NICUs increase the chances of congenital malformations in neonates. Conclusion: The prevalence of congenital malformations in neonates was 16.6%. The most common malformations included cardiovascular malformations and genitourinary malformations.
https://ijp.mums.ac.ir/article_16240_366b5bc06bf8f53ecdadd1fe0a9a2483.pdf
2021-06-01
13653
13662
10.22038/ijp.2020.48504.3903
Congenital malformations
Prevalence
neonate
Fereshte
Mohseni
fereshte.mohseni1997@gmail.com
1
Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
Seyed Mohammad Hossein
Mousavi
ho3ein90@gmail.com
2
Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
Atefeh
Ahmadi
atefeahmadi59@gmail.com
3
Nursing Research Center, Razi faculty of Nursing And Midwifery, Kerman University of Medical Sciences, Kerman, Iran.
AUTHOR
Abolfazl
Hosseinnataj
abolfazlh_68@yahoo.com
4
Department of Biostatistics, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
AUTHOR
Nahid
Marvi
5
MSc Counseling in Midwifery, Department of Nursing and Midwifery, Neyshabur University of Medical Sciences, Neyshabur, Iran.
AUTHOR
Masumeh
Ghazanfarpour
masumeh.ghazanfarpour@yahoo.com
6
Student Research Committee, Kerman University of Medical science, Kerman, Iran.
AUTHOR
Fahime
Khorasani
fahimeh_khorasani@ymail.com
7
Student Research Committee, Kerman University of Medical science, Kerman, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Assessment of Left Ventricular Outflow Tract Velocity Time Integral in Pediatric Patients with Vasovagal Syncope
Background Syncope is an important and common clinical condition, and the neurally mediated syncope is the most frequent type of syncope. Head up tilt testing is considered as a first line diagnostic test. The aim of this study was to assess the left ventricular outflow tract velocity time integral in echocardiography of pediatric patients with vasovagal syncope. Materials and Methods: In this case-control study, between January 2019 and December 2020 92 patients who referred in in Mofid Children Hospital in Tehran, Iran, for vasovagal syncope in the case group and 92 healthy children with maximum matching of sex and age in the control group were included in the study. Demographic, clinical and para-clinical data were recorded for each patient in the respective checklists, and HUTT and echocardiography were reviewed, then the results of two groups were compared. Results: The mean age of the patients with vasovagal syncope was 12.12 ±5.18 years. 66.3% of patients in the case group were female. There was a statistically significant relationship between LVOT-VTI and positive result of HUTT (p <0.001). There was no relationship between LVOT VTI in case and control groups (p=0.14). Conclusion The mean LVOT VTI index in patients with negative tilt test is higher than patients with positive tilt test. Although echocardiographic indices in children with vasovagal syncope are in normal range, accurate measurement of LVOT-VTI can be helpful in predicting a positive HUTT result.
https://ijp.mums.ac.ir/article_17933_7ab033750d36f4de8f7cdd700028ed8b.pdf
2021-06-01
13663
13669
10.22038/ijp.2021.57356.4502
Children
LVOT VTI
HUTT
Vasovagal syncope
Mohammad Reza
Khalilian
khalilianomid@yahoo.com
1
Assistant Professor of Pediatric Cardiology, Department of Pediatrics, School of Medicine, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
Fariba
Alaei
alaeifariba@yahoo.com
2
Assistant Professor of Pediatric Cardiology, Department of Pediatrics, School of Medicine, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Elham
Abdoulahzadeh
elhampt63@yahoo.com
3
MD, Department of Pediatrics, School of Medicine, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Mohammad
Ghazavi
mo_ghazavi@yahoo.com
4
Pediatric cardiologist, Department of Pediatrics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Mahmoud
Hajipour
m.hajipour.13@gmail.com
5
Pediatric Gastroenterology, Hepatology and Nutrition Research Center, Research Institute for Childrens Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
ORIGINAL_ARTICLE
The Effect of Water Treadmill Exercise on Children with Attention Deficit Hyperactivity Disorder
Background Attention deficit hyperactivity disorder (ADHD) is one of the prevalent disorders in child psychiatry with the potential of damage to mental talent evolution process and socio-emotional skills. This study aimed to determine the effect of Water treadmill exercise on children with Attention deficit hyperactivity disorder (ADHD). Materials and Methods: This was an experimental study with pretest, posttest design which was done in Gorgan. Participants were 46 children (mean age = 9.45 ±0.5, male = gender) who were identified and selected based on diagnostic criteria in two stages and were randomly divided into experimental and control groups (n=23). The experimental group performed running on a Water treadmill for eight weeks with three sessions each week (24 sessions in total) and each session for 30 minutes. The exercise intensity was for 10 minutes 40-45% and 20 minutes 55-65% of the maximum heart rate reserve. All sessions begin with a brief warm-up, including light aerobic activity and dynamic, static stretching, and end with a cool-down. Disorder Levels were measured using the Conners’ Parent Rating Scale-Revised (CPRS-R), and diagnostic interviews. Data were analyzed using SPSS software version 22. Results: The results showed that after controlling the pretest levels, behavior problems, social problems, anxiety-shyness, psychosomatic, and the overall score of attention deficit hyperactivity disorder in the experimental group were significantly lower the posttest than the control group (p <0.05). Conclusion Based on the results, exercise interventions with Water treadmill for eight weeks effectively reduce the symptoms of attention deficit hyperactivity disorder in children and can be used as an appropriate intervention.
https://ijp.mums.ac.ir/article_17887_ad5d938dc87eddc14842b2aae3451154.pdf
2021-06-01
13671
13681
10.22038/ijp.2021.57015.4466
ADHD
Children
Exercise
Physical Activity
Motor Development
Amir Hamze
Sabzi
amir.hamze2005@gmail.com
1
Department of Physical Education, Payame Noor University, Tehran, Iran.
AUTHOR
Amir
Dana
amirdana2010@gmail.com
2
Department of Physical Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
LEAD_AUTHOR
Mir Hamid
Salehian
mh.salehian@gmail.com
3
Department of Physical Education, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
AUTHOR
Haniyeh
Shaygan Yekta
haniehyekta.1362@gmail.com
4
Graduate of Educational Technology, North Tehran Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
ORIGINAL_ARTICLE
Acute Bronchiolitis Treatment: A Comparison of Montelukast, Aminophylline and Ventolin in Pediatric Patients: A Clinical Trial Study
Background: The effects of various drugs on reducing the severity of bronchiolitis symptoms in children have been identified. We sought to make a comparison of Montelukast, Aminophylline and Ventolin (Intravenous Salbutamol) in the treatment of acute bronchiolitis in patients ranged between 1 and 24 months old. Materials and Methods: This study used a randomized clinical trial method. Statistical population of the study included all patients younger than 2 years and older than one month who were admitted to Ali-Ibn-Abitaleb Hospital in Zahedan-Iran. Two hundred patients were divided into four groups using a random number table method. The first group received supplemental monotherapy with Montelukast 4 mg/kg daily for 7 days. The second group received 1 mg/kg Aminophylline injection every 12 hours. The third group or the control group received supportive measures. The fourth group received 0.15 mg/kg Ventolin Nebules with dose of 2.5 mg. Symptoms were measured on days 2, 5 and 7, and the number of hospital admissions days was also assessed in four groups and compared. Results: The results showed that the consumption of Montelukast and Ventolin Nebules had no significant effect on bronchiolitis treatment in comparison with the control group (P>0.05). Using Aminophylline did not reduce the symptoms of bronchiolitis in comparison with the control group (p <0.05). The results also showed that using aminophylline in group B did not produce better results in decreasing the severity of the symptoms of bronchiolitis in comparison with Montelukast group and Ventolin group (p <0.05). Conclusion The results showed that consumption of Aminophylline, Montelukast and Ventolin had no significant effect on bronchiolitis in comparison with the control group.
https://ijp.mums.ac.ir/article_16817_37a283158cb509f2287df006a78e8dae.pdf
2021-06-01
13683
13690
10.22038/ijp.2020.51086.4055
Aminophylline
Bronchiolitis
Montelukast
Pediatric
Ventolin
Gholamreza
Soleimani
soleimanimd@yahoo.com
1
Associate Professor of Pediatric Infectious Disease, Department of Pediatrics, School of Medicine, Children and Adolescents Health Research Center, Research Institute for Drug Resistant Tuberculosis, Ali-Ibn-Abitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran.
AUTHOR
Elham
Shafighi Shahri
elham.shafighi2276@gmail.com
2
Assistant Professor of Pediatrics, Department of Pediatrics, School of Medicine, Children and Adolescents Health Research Center, Research Institute for Drug Resistant Tuberculosis, Ali-Ibn-Abitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran.
AUTHOR
seyed hosein
soleimanzadeh mousavi
dr_soleimanzadeh@yahoo.com
3
Resident of Pediatric, Department of Pediatrics, School of Medicine, Ali-Ibn-Abitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Comparative Three-Dimensional Evaluation of Spheno-Occipital Synchondrosis and Zygomatico-Maxillary Suture in Cleft Lip and Palate Children versus the Normal Population
Background: The purpose of the present study was a three-dimensional evaluation of the spheno-occipital synchondrosis (SOS) and zygomatico-maxillary suture (ZMS) in cleft lip and palate patients versus the normal population. Materials and Methods: In the case-control study, cone beam computed tomography scans of 153 unilateral or bilateral cleft lip and palate patients and 153 scans of healthy non-cleft individuals with skeletal Class I occlusion from 6 to 18 years were selected. Then the ZMS and SOS maturation stages were determined. Mann-whitney test, spearman correlation, repeated measurement, and bayesian transition analysis were used for statistical analysis. P-value < 0.05 was considered as significant. Results: The result of this study showed ZMS maturation in cleft lip and palate patients was significantly earlier than control group; although, there were no statistically significant differences between case and control groups in SOS maturational stages. This study showed that in the normal population, the mean age of stage B, which is the ultimate level of favorable response to growth modification in ZMS development, is 11.50 ± 1.50 years for females and 10.79± 1.89 years for males and in cleft lip and palate patients, the mean age of stage B is 9.53 ± 1.46 years for females and 9.71 ± 1.36 years for males. There was no significant difference in mean age at any of maturational stages of ZMS and SOS between unilateral and bilateral cleft lip and palate patients (P>0.05). Conclusion Maturation of zygomatico-maxillary suture in cleft lip and palate was earlier than non-cleft children, however sphenooccipital synchondrosis did not show any significant differences in maturational stages between cleft lip and palate patients and healthy controls.
https://ijp.mums.ac.ir/article_16305_f971af8d7787aeaa06243ef7100ceaac.pdf
2021-06-01
13691
13702
10.22038/ijp.2020.50056.3991
Cleft lip and palate
Spheno-occipital syncondrosis
zygomatico-maxillary suture
Arezoo
Jahanbin
jahanbina@mums.ac.ir
1
Department of Orthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Alireza
Chamani
alireza.chamani72@yahoo.com
2
Resident of Orthodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
Hosein
Hoseini Zarch
hoseinih@mums.ac.ir
3
Department of Oral and Maxillofacial Radiology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Saeedeh
Hajebi khaniki
hajebis971@mums.ac.ir
4
Student Research Committee, Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
ORIGINAL_ARTICLE
Postpartum Mental Health and its Relationship with Social-Structural Determinants of Health in Iran with the Approach of the World Health Organization Model: A Systematic Review
Background: Postpartum psychiatric disorders are a key concept in maternal-infant mental health, and determining the related factors is necessary. We aimed to determine the relationship between postpartum mental health and social-structural determinants of health in Iran. Materials and Methods: In this systematic review, all Persian and English observational studies in Iran carried out through advanced search in online databases such as Medline, Scopus, Web of Science, EMBASE, SID and Magiran, as well as the Google Scholar between 2005 and 2020, using keywords of social determinants, structural factors, socio-economic status, risk factors, mental health, postpartum, Iran, and their English equivalents were obtained from MESH. Article quality was assessed using the standard Newcastle-Ottawa Scale (NOS). Results: Out of 56 eligible articles (sample size: 36,515), 49 articles reported the prevalence of postpartum depression and one article reported the prevalence of postpartum psychosis. The lowest and highest prevalence of postpartum depression was between 4.8-68.5% using the Edinburgh tool in 2014-2017 and using the Beck tool between 3-78.27% in 2013-2014. Structurally significant effective factors on postpartum depression were identified including mother's age, mother's education, father's education, mother's job, father's job, family economic status (income adequacy), ethnicity and race, social class, culture, and religion, and in the field of postpartum psychosis, age, level of education, and mother's job. The most common structural determinant related to postpartum mental health was education and the least factor was related to social class. Conclusion: Due to the effects of numerous related factors on common postpartum mental disorders, it is suggested that longitudinal studies be conducted to investigate the role of all the known factors, especially Intermediate factors, on postpartum mental health.
https://ijp.mums.ac.ir/article_17375_5111c2f512e1e7fff110e61c59554e7d.pdf
2021-06-01
13703
13729
10.22038/ijp.2021.54669.4317
Iran
Mental health
Postpartum
social determinants
structural factors
Sahar
Roozbahani
s.roozbahani1217@gmail.com
1
Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, IR, Iran.
AUTHOR
Mahrokh
Dolatian
mhdolatian@gmail.com
2
Associate Professor, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, IR, Iran.
LEAD_AUTHOR
Zohreh
Mahmoodi
zohrehmahmoodi2011@gmail.com
3
Associate Professor, Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, Iran.
AUTHOR
Atefeh
Zandifar
zandifaratefe@gmail.com
4
Assistant Professor of Psychiatry, Social Determinants of Health Research Center, Alborz University of Medical Sciences, Karaj, Iran.
AUTHOR
Hamid
Alavi Majd
alavimajd@gmail.com
5
Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR, Iran.
AUTHOR
ORIGINAL_ARTICLE
Atypical Presentation of Holt-Oram syndrome: A Case Report
Holt-Oram syndrome (HOS) is an autosomal dominant disorder, a mutation in TBX5 gene located on chromosome 12 (12q24.1) involving the upper limb and the heart, causing malformations like atrial septal defect. Herein, we report a rare case of HOS with atrial septal defect and ventricular septal defect with severe pulmonary arterial hypertension in a three-year-old child.
https://ijp.mums.ac.ir/article_17328_1fc8f84f801271ca3a51ab76f8ef451f.pdf
2021-06-01
13731
13735
10.22038/ijp.2020.53117.4209
Child
Heart-hand syndrome
Holt-Oram syndrome
Ventricular Septal Defect
Abhilasha
Singh Panwar
abhilasha12@gmail.com
1
R, MBBS, Pediatrics Resident, Deptt. of Paediatrics, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra : 442004, India.
AUTHOR
Amar
Taksande
amar.taksande@gmail.com
2
MD, FIAE, Fellow in Ped Card., Professor, Deptt. of Paediatrics, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra : 442004, India.
LEAD_AUTHOR
Syed Athhar
Saqqaf
syedathharsaqqaf@yahoo.co.in
3
MBBS, Pediatrics Resident, Deptt. of Paediatrics, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra : 442004, India.
AUTHOR
Rewat
Meshram
rewatmeshram@rediffmail.com
4
MD, Associate Professor, Deptt of Paediatrics, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra: 442004, India.
AUTHOR
ORIGINAL_ARTICLE
Investigation of the Maternal and Neonatal Factors Affecting the Apgar score of Newborns: A Case-Control Study
Background: Apgar score is a method for clinical evaluation of neonate at birth, and predicts their clinical conditions and physical or mental development. This study aimed to investigate the relationship between some neonatal and maternal factors during pregnancy on the Apgar score. Materials and Methods: This case-control study was conducted on 234 neonates born in Ilam hospitals during 2015-2016. The case group included 81 neonates with Apgar score Results: The mean maternal weights in the case and control groups were 66.8 ± 13.5 and 67.1 ± 11.1 Kg, respectively. The mean± SD for maternal age 29 ± 5 vs. 29 ± 5.7 years, marriage age 22 ± 3 vs. 22.2 ± 4.9 years, BMI 24.5±3.2 vs. 26.1 ± 4.1 and weight gain during pregnancy 13.8 ± 6.2 vs. 12.7 ± 6.8 kg among cases and controls, respectively. The odds ratio for the following factors was significantly higher among cases than the control group: preterm delivery (OR: 3.3, 95% CI: 1.2-17), twin birth (OR: 8.9, 95% CI: 2.6-27.2), abnormal presentation of the fetus (OR: 6, 95% CI: 2.3-15.6), birth weight (OR: 6.9, 95% CI: 1.4-28.6), and placental abruption (OR: 9.4, 95% CI: 2.2-22.5) for Apgar score at five minute. Conclusion: Based on the findings of the present study, preterm labor, multiple birth, and abnormal fetal presentation, and low birth weight, premature rupture of membrane, placental abruption and anemia, led to an increase in Apgar score less than 7.
https://ijp.mums.ac.ir/article_15821_8677a2dd7a5afc24ae6286689dba391b.pdf
2021-06-01
13737
13746
10.22038/ijp.2020.48805.3919
Apgar score
Neonatal
Maternal factor
pregnancy
odds ratio
Khairollah
Asadollahi
masoud_1241@yahoo.co.uk
1
Department of Social Medicine, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
AUTHOR
Arezoo
Karimi
karimi.rooya@yahoo.com
2
Department of Epidemiology, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran.
AUTHOR
Zahra
Bagheri-Hosseinabadi
baghery.zahra@yahoo.com
3
Department of Clinical Biochemistry, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
AUTHOR
Nazanin
Rezaei
nazaninrezaei37@gmail.com
4
Department of Midwifery, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.
AUTHOR
MirHadi
Mussavi
mirhadimousavi33@yahoo.com
5
Department of Pediatrics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
AUTHOR
Salman
Daliri
daliri.salman@yahoo.com
6
Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran AND Student Research Committee, School of Health, Ilam University of Medical Sciences, Ilam, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
A Rare Cause of Fat Malabsorption in Children: Chylomicron Retention Disease: A Case Report
Background: Chylomicron retention disease is an autosomal recessive disorder causing malabsorption of intestinal fat. It is extremely rare. This report is presented because although the condition is rare in cases presenting with fatty diarrhea, inability to gain weight, and abdominal distension, it should nevertheless be considered. Case Presentation: A four-month-old girl presented due to diarrhea, inability to gain weight, and lack of appetite since birth at Çukurova University, Pediatric gastroenterology outpatient clinic, Adana, Turkey. No blood or mucus was present in stool. Her general condition was average, she appeared pale and lethargic, the abdomen was distended, and no organomegaly was present. Duodenal pathology was normal but electron microscopy revealed that the enterocytes were filled with fat globules. Causes leading to fat malabsorption were investigated, and homozygous mutation was determined in the SAR1B, chylomicron retention disease, gene. Conclusion: The patient was treated with a low-fat diet and fat-soluble vitamin supplementation resulting in significant improvement. Although it is rarely seen in patients presenting with chronic diarrhea, chylomicron retention disease should be kept in mind in the differential diagnosis.
https://ijp.mums.ac.ir/article_17928_19146e8bf536f437d269eeb6e2a83b4e.pdf
2021-06-01
13747
13752
10.22038/ijp.2021.56367.4430
Children
Chylomicron Retention Disease
malabsorption
SAR1B gene
Sibel
Yavuz
sibel_5163@hotmail.com
1
ukurova University Medical Faculty, Dept. of Pediatric Gastroenterology, Adana, Turkey.
LEAD_AUTHOR
Gökhan
Tümgör
gtumgor@yahoo.com
2
Cukurova University Medical Faculty, Dept. Of Pediatric Gastroenterology, Adana, Turkey.
AUTHOR
Yurdun
Kuyucu
yurdunkuyucu01@yahoo.com.tr
3
Cukurova University Medical Faculty, Dept. of Histology and Embryology, Adana, Turkey.
AUTHOR
Sait
Polat
spolat72@gmail.com
4
Cukurova University Medical Faculty, Dept. of Histology and Embryology, Adana, Turkey.
AUTHOR
ORIGINAL_ARTICLE
Understanding the Physical Activity Behavior of Iranian Female Students: Two Approaches to Analyzing the Theory of Planned Behavior
Background Living without sufficient amount of physical activity is known as a contributing factor to countless diseases. This research study aimed to determine the relationships between the constructs of the theory of planned behavior and female students’ physical activity with a path analysis approach. Materials and Methods The present research is a descriptive-analytic study conducted through cross-sectional data collection procedure. 185 female students were selected via multi-phase random sampling in elementary schools in Mashhad, Iran, from February to November 2018. Path analysis was performed by AMOOS version 22.0 and SmartPLS 2.0 to test the causal relationship among physical activityand constructs of the theory of planned behavior. Results The age range of female students was between 10 and 13, with mean and standard deviation of 11.51 ±0.76, respectively. The results showed that the constructs of attitude (r=0.177, p=0.018), and perceived behavioral control (r=0.234, p=0.001) had a direct and significant relationship with physical activity intention. However, the direct relationship between the constructs of subjective norms and physical activity intention was not significant (P>0.05). Also the direct relationship between the constructs of physical activity intention and physical activity behavior was not significant (P>0.05). Conclusion Based on the results, the constructs of attitude, and perceived behavioral control had a direct and significant relationship with physical activity intention in female students.
https://ijp.mums.ac.ir/article_17852_20836df8024a1bb49e7e13056827afc6.pdf
2021-06-01
13753
13763
10.22038/ijp.2021.57084.4475
Physical Activity
Path analysis
theory of planned behavior
Student
Mansoure
Alipour-anbarani
alipoor.he@gmail.com
1
Ph.D. Candidate in Health Education & Health Promotion, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AUTHOR
Saeed
Mohammad-pour
saeed_mohammadpur@yahoo.com
2
Ph.D. candidate, department of health economics, School of Management and Medical Information, Iran University of Medical Sciences, Tehran, Iran.
AUTHOR
Hossein
Akhavan
akhavanh2@mums.ac.ir
3
Pediatric Intensivist, Pediatric & Congenital Cardiology Division, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Maryam
Habibnezhad
habibnezhadkm961@mums.ac.ir
4
Pediatrician, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical sciences, Mashhad, Iran.
AUTHOR
Tayebe
Marashi
marashi142002@yahoo.com
5
School of Public Health and Safety , Shahid Beheshti University of Medical Sciences, Tehran, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Predicting Academic Resilience based on Metacognitive Beliefs and Achievement Motivation in High School Students in Shiraz, Iran
Background Resilience is one of the other essential variables that, in the educational setting, despite challenges and environmental difficulties, is regarded as a very high likelihood of success in school and other life situations.The purpose of this study was to predict academic resilience based on metacognitive beliefs and achievement motivation in first-grade high school students in Shiraz, Iran. Materials and Methods: This was a cross-sectional study with a correlational design. The study population comprised all first-grade high school students in Shiraz, Iran. The research sample included 162 students (79 boys and 83 girls) selected by the multi-stage cluster sampling method. The Academic Resilience Inventory (ARI), the Metacognition Questionnaire (MCQ-30), and the Herman's Achievement Motivation Questionnaire were used to measure the studied variables. Data were analyzed using SPSS software version 22.0. Results: 162 (49.40%) of the students were females. The results showed that metacognitive beliefs could predict students 'academic resilience β = -0.601; p < 0.01) and achievement motivation, improving students' academic resilience. According to F = 27.285, the fitted regression model's significance at the 95% confidence level. Considering R 2 = 0.15, it can be claimed that 15% of the changes in students' resilience are explained by achievement motivation. Conclusion Based on the results, metacognitive beliefs and motivation for progress significantly predict students' academic resilience.
https://ijp.mums.ac.ir/article_17330_56f3847c97d4697a9a127f9ad71df0ae.pdf
2021-06-01
13765
13772
10.22038/ijp.2020.53686.4257
Metacognitive beliefs
Achievement Motivation
academic resilience
Students
Pooneh
Baniani
pooneh.baniani@yahoo.com
1
MSc in General Psychology, Department of psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
AUTHOR
Azam
Davoodi
davoodi.azam@yahoo.com
2
Ph.D. Assistant Professor, Department of psychology, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Influence of Speed-Strength Training on the Speed of Movement of Schoolchildren with Different Strength of the Nervous System
Background The aim of this study was to determine the influence of speed and strength abilities of children aged 13-14 years on the indicators of speed of movement, taking into account the differentiated physical activity, which is based on the strength of the nervous system. Materials and Methods: This case-control study was conducted in an ordinary school in Russia, 40 seventh-graders took part in the experiment. Children from the control group (n=20) were engaged in the usual program, and children from the experimental group (n=20) additionally performed speed-strength exercises at each physical education lesson. Physical activity for children in the experimental group was differentiated, taking into account the strength of the schoolchildren nervous system. All schoolchildren took tests: tapping test, speed-strength abilities were determined by three tests. The speed of movement of schoolchildren was determined by the test «Running on the spot». Two results of two groups were compared. Results: After the pedagogical experiment, the indicators for all tests in all subgroups increased. In the control group, the indicators of speed and strength abilities in both subgroups improved by 2-4% (p>0.05), and the indicators of speed of movement by 4-6% (p>0.05). At the same time, the children from the experimental group the indicators of speed and strength abilities improved by 11-16% (p <0.05), and the indicators of speed of movement improved by 17-19% (p <0.05). Conclusion After focused work in physical education classes at school on speed and strength abilities the indicators will improve not only speed-power abilities, but also increase the speed of movement taking into account the typology of the nervous system of schoolchildren.
https://ijp.mums.ac.ir/article_17942_032737e5be66c282eb2543e6f8eb0ee4.pdf
2021-06-01
13773
13779
10.22038/ijp.2021.57347.4500
Physical Education
speed of movement
Schoolchildren
Nervous system
Georgiy
Polevoy
g.g.polevoy@gmail.com
1
Moscow Aviation Institute (National Research University), Moscow, Russia, AND Vyatka State University, Kirov, Russia, AND Vyatka State Agrotechnological University, Kirov, Russia.
LEAD_AUTHOR
ORIGINAL_ARTICLE
A Retrospective Assessment of Measles Outbreak Response Activities and Determinant Factors at Nunukumba District, East Wollega Zone, Oromia Regional State, Western Ethiopia, May 2020
Background: Measles is a highly infectious viral disease that causes morbidity and mortality in both developing and industrialized countries. In Ethiopia, the major outbreaks with large attack rates resulting in as high as 15-20% case fatality rates have been reported. There is a paucity of information on assessment of post-measles outbreak response activities and its determinant factors in NunuKumba district, Ethiopia. We aimed to assess of measles outbreak response activities and determinant factors at Nunukumba District, Ethiopia. Materials and Methods: A retrospective descriptive cross-sectional survey was conducted from April-24 to May-7, 2020 at NunuKumba district, Ethiopia. The data was collected by using semi-structured questionnaires, and a secondary data was taken from the line list of cases. Purposive sampling technique was used. Quantitative data was analyzed using Microsoft Excel 2010 while the qualitative data was themed; analyzed and then triangulated with quantitative result. Graphs, tables and Epi-curve displayed the result. Results: The overall Attack rate and Case Fatality Rate were 1.05% and 0.41%, respectively. The most affected age group was under five year’s children 552 (56.55%). More than one third of cases 389 (40%) were unvaccinated. The outbreak reached climax at middle of January and declined by the middle of February 2020. Conclusion: Poor early detection and response of the outbreak.The probable contributing factors for this outbreak were poor surveillance system, lack of training on vaccine and cold chain management, lack of functional fridge tag and refrigerator, weak expanded program on immunization activities monitoring and evaluation. Therefore, training of human power, immunization program and surveillance system should get due attention.
https://ijp.mums.ac.ir/article_16120_ba82fe78b8edb05bffa8a0284733a910.pdf
2021-06-01
13781
13801
10.22038/ijp.2020.49135.3935
District
Ethiopia
Measles outbreak
NunuKumba
Zalalem
Kaba Babure
kabazalalem@gmail.com
1
East Wollega Zonal Health Office, Nekemte town, Oromia regional state, western Ethiopia.
LEAD_AUTHOR
Aklilu
Fikadu Tufa
aklilufikadu1@gmail.com
2
Cluster program officer at USAID/JSI Transform: Primary Health Care project, east Wollega zone, Nekemte, Ethiopia.
AUTHOR
Yusuf
Mohammed Ahmed
zakyu44@gmail.com
3
WHE Public Health Emergency Surveillance Officer, East Wollega, Nekemte, Ethiopia.
AUTHOR
ORIGINAL_ARTICLE
The Effectiveness of Viktor Frankl's Logo therapy on the Mental Health of Pediatric Patients with Cystic Fibrosis
Background Individuals with cystic fibrosis (CF) are at high risk of clinically significant anxiety, which can be related to lower treatment adherence and poorer health outcomes. So, it is associated with poor psychosocial and quality of life outcomes. The aim of this study was to assess the effectiveness of Viktor Frankl's Logo therapy on the mental health of pediatric patients with CF. Materials and Methods: This research was a quasi-experimental based on pretest and posttest with a control group. The population under study includes pediatric patients with CF referring to Emam Khomeini hospital, Tehran, Iran, during 2018-19. The range of the participants’ age was between 12 and 16 years. The sample size was selected based on the convenience sampling method. The participants divided randomly into two groups: experimental, n=11 and control n=11. Participants in both experimental and control group completed questionnaires on The General Health Questionnaire (GHQ) before and after training. Treatment process for 45 minutes a week was applied among experimental group. Results: The mean and standard deviation of the patient's age in this study were 15.83± 0.87 years old. The results of this research showed that the score of mental health in the experimental group (25±6.8) increased after the intervention training (p <0.01), compared the control group. Conclusion Based on the results of this study, the effectiveness of logo therapy in fostering mental health among pediatric cystic fibrosis patients with a mean age of 13-18 years was approved after nine sessions, 45 minutes once a week. According to the results, logo therapy helped children with cystic fibrosis improve their mental health.
https://ijp.mums.ac.ir/article_17901_8d31758649b5c2f2dda36369a959d1ba.pdf
2021-06-01
13803
13810
10.22038/ijp.2021.56871.4455
Cystic fibrosis
Logo-therapy
Mental health
pediatric patients
Sepideh
Nematollah
sepidehmatollah@yahoo.com
1
Master of Clinical Psychology, Research Sciences, Tehran, Iran.
AUTHOR
Maryam
Zadahmad
maryamzadahmad@gmail.com
2
Master of Clinical Psychology, Islamic Azad University, Tehran Research Sciences Branch, Tehran, Iran.
AUTHOR
Mohammad Reza
Javadani
mohammadrezajavadani@yahoo.com
3
General Psychology Azad University of Tehran Center, Tehran, Iran.
AUTHOR
Mahin
Ghaheri
mahinghaheri@yahoo.com
4
Master of Clinical Master of Sari Free University, Sari, Iran.
AUTHOR
Javad
Seyed Jafari
javad_jafari90@yahoo.com
5
PhD candidate in Psychology, Allameh Tabataba'i University, Tehran, Iran.
LEAD_AUTHOR
Sara
Moussavi
saramhasti@yahoo.com
6
Instructor, department of Psychology, Payame Noor University, Tehran, Iran.
AUTHOR
ORIGINAL_ARTICLE
A Bizarre Case of Anaphylaxis due to Hydatid Cyst Perforation Presented as Respiratory Arrest: A Case Report
Anaphylaxis is an acute systemic reaction with various presentations that can be misdiagnosed in some patients. Anaphylaxis due to hydatid cyst rupture usually happens during surgery. However, there are rare cases with even spontaneous hydatid cyst rupture and anaphylaxis. We report a five-year-old Iranian child with cardiopulmonary arrest and coma presentation that was incidentally diagnosed as an anaphylaxis case due to hydatid cyst rupture. In children who are presented with unconsciousness, anaphylaxis may have an uncommon presentation. In endemic regions, anaphylaxis due to hydatid cyst rupture should be considered to reduce morbidity and even mortality.
https://ijp.mums.ac.ir/article_17866_623affa82f1b5eda51473c318d1372d4.pdf
2021-06-01
13811
13815
10.22038/ijp.2021.55047.4352
Anaphylaxis
hydatid cyst rupture
cardiopulmonary arrest
Sajjad
Saghebdoust
sajjadsaghebdoust921@gmail.com
1
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Elham
Nikrouh
elhamnikrouh@yahoo.com
2
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Sara
Najafi
sara.najjafi@gmail.com
3
Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mohammad Hasan
Aelami
aelamimh@mums.ac.ir
4
Department of Pediatrics & Infection Control and Hand Hygiene Research Center, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Evaluation of Aortic Elasticity in Children with Celiac Disease Compared with Controls
Background Celiac disease (CD) is a lifelong, chronic and immune-mediated disorder. Recent studies have turned on a new light on the importance of inflammation in the pathogenesis of arterial stiffness. The aim of this study was to evaluate arterial stiffness in children with celiac disease compared with controls. Materials and Methods: In this case-control study, fifty children aged from 3.5 to 18 year- old with celiac compared with 50 age and sex-matched controls. The study performed in Ali Asghar pediatric hospital in Zahedan city, Iran during the year 2019. Echocardiography, aortic elasticity, blood pressure, tissue transglutaminase IgA (tTG-IgA), and anthropomorphic parameters were measured. Arterial stiffness indices determined using 2D and Doppler echocardiography. Data were analyzed using SPSS software version 20.0. Results: In all and CD children, 51% and 56% were girls, respectively. Systolic and diastolic blood pressure were lower in patients (p <0.001). Aortic diameter in diastole was lower in patients significantly (p <0.001). Aortic strain (<0.001), PSEM (<0.001), AD (<0.001), and ASI (p <0.001) were different between celiac patients and controls. Tissue transglutaminase IgA (tTG-IgA) was changed significantly with Marsh classification (p <0.001); tTG-IgA was correlated with strain (r= 0.417, p=0.003), and AD (r= 0.282, p=0.047) before age control when the trends did not change after age control for AD (r=0.241, p=0.096). LVMI was correlated with strain (r=-0309, p=0.029), PSEM (r=0.322, p=0.023), and AD (r=0.326, p=0.021) before controlling age when after age control this significant correlation omitted. Conclusion Concluded that aortic elastic risk is higher in celiac children when is free of modified marsh classification. Most of the aortic elastic parameters had significant correlation with changes of tTG-IgA antibody in children with celiac disease.
https://ijp.mums.ac.ir/article_16374_af159043e00ee201b767c6ec0047336e.pdf
2021-06-01
13817
13832
10.22038/ijp.2020.49865.3979
Aortic Elasticity
Celiac disease
Children
echocardiography
Noor Mohammad
Noori
dr_noori_cardio@yahoo.com
1
Pediatric cardiology, Children & Adolescent Health Research Center, Resistant Tuberculosis Institute, School of Medicine, Zahedan Univ Med Sci, Zahedan 9816743111, Iran.
AUTHOR
Manijeh
Khalili
dr_khalili2000@yahoo.com
2
Pediatric Gastroenterology, Children & Adolescent Health Research Center, Resistant Tuberculosis Institute School of Medicine, Zahedan Univ Med Sci, Zahedan 9816743111, Iran.
AUTHOR
iraj
Shahramian
ir_buper@yahoo.com
3
Pediatric Gastroenterology, School of Medicine, Zabol Univ Med Sci, Zabol, Iran.
AUTHOR
Alireza
Teimouri
alirezateimouri260@gmail.com
4
PhD in Demography Children & Adolescent Health Research Center, Resistant Tuberculosis Institute, School of Medicine, Zahedan Univ Med Sci, Zahedan 9816743111, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Comparison of Blood Lead Concentration in Opium-Addicted and Non-Addicted Children in Birjand, East of Iran
Background Lead-contaminated opium is a new source of lead in the region that children can be exposed to. The acceptable blood lead concentration (BLC) in children is 5 μg/dl, and this population is more susceptible to lead's toxic effects. We aimed to evaluate and compare BLC in opium-addicted and healthy children in Birjand, Iran. Materials and Methods: This case-control study was performed among children admitted to the pediatrics wards of two hospitals in Birjand, Iran. Thirty opium-addicted children were considered as the case group, and 30 age and gender-matched non-addicted children admitted to the hospital for other reasons were assigned to the control group. Two milliliters of venous blood was obtained from children, placed in specific complete blood count (CBC) vials, and stored at 2-8 ° C for subsequent analysis. Data were analyzed using SPSS software version 22.0. Results: The means of BLC were 3.63±4.38 μg/dl (median: 1.75 μg/dl), and 2.09±1.21 μg/dl (median: 1.80 μg/dl) in the case and control groups, respectively. The results showed that BLC was not significantly different between the two groups (p=0.84). In the case group, 26.7% of them BLC was above 5 μg/dl, while in the control group, 2 (6.7%) children had BLC above 5 μg/dl. The Fisher’s exact test revealed that BLC was not significantly different between the two groups (p=0.08). There was no significant relationship between BLC, duration of use, and opium type in the case group. Conclusion It can be concluded that addicted children’s serum lead levels significantly increased, and this level of lead can result in unalterable problems in children. However, further studies with larger sample numbers and more specific targets are recommended.
https://ijp.mums.ac.ir/article_16824_33d5b5a296e35b90b4ef7534d629c551.pdf
2021-06-01
13833
13841
10.22038/ijp.2020.49990.3989
Children
Iran
Opium
Lead
Tayebeh
Chahkandi
na_chahkandi@yahoo.com
1
Department of Pediatrics, Faculty of Medicine, Birjand Atherosclerosis and Coronary Artery Research Center, Birjand University of Medical Sciences, Birjand, South Khorasan Province, Iran.
AUTHOR
Mahdieh
Hamzehnezhad
m.hamzenezhad@gmail.com
2
Resident of Pediatrics, Department of Pediatrics, Faculty of Medicine. Birjand University of Medical Sciences (BUMS), Birjand, South Khorasan Province, Iran.
LEAD_AUTHOR
Bita
Bijari
bita.bijari@yahoo.com
3
Cardiovascular Diseases Reaserch Center, Department of Community Medicine, Birjand University of Medical Sciences, Birjand, Iran.
AUTHOR
Omid
Mehrpour
omid.mehrpour@yahoo.com.au
4
Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Ghaffari Avenue, Vali-Asr hospital, Birjand, Iran.
AUTHOR
Alireza
Amirabadizadeh
amirabadiza921@gmail.com
5
Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences (BUMS), Birjand, Iran.
AUTHOR
ORIGINAL_ARTICLE
The Effectiveness of Family- Centered Education on Quality of Life and Readmission in Children with Nephrotic Syndrome
Background Children with Nephrotic Syndrome (NS) experience frequent hospitalizations, and readmission affects the quality of life of the patient and family. We aimed to investigate the effectiveness of family- center education on quality of life and readmission in children with nephrotic syndrome. Materials and Methods This quasi-experimental study was performed in two groups the pediatric ward of Ali Ebn Abitalib Hospital, Zahedan, Iran, in 2018. Ninety-six children with Nephrotic Syndrome were selected by convenience sampling and were randomly into two groups: intervention (n = 48) and control (n = 48) groups. In the intervention group, family-centered education was held for 4 sessions. Eight weeks after training, readmission and quality of life were assessed. The Pediatric Quality of Life Inventory (PedsQL 4.0), and demographic information were used before and after intervention. Results The mean age of children with NS in the intervention group was (8.06 ±2.10), and in the control group it was (8.58 ± 2.87) (P>0.05). The mean of quality of life in the intervention group after the intervention (56.02 ±192.28) was significantly higher than before the intervention (51.73 ± 164.71) (p <0.001, t= 7.54). The mean of quality of life after intervention was significantly different between the intervention and control groups (P= 0.03, t= -3.03). There was also a significant difference between the two groups in terms of mean readmission (P < 0.001). Conclusion The results suggest that family-centered education effected on quality of life and readmission; so we propose that nurses can use family-centered education as a cost-effective and acceptable method for families of children with chronic illness.
https://ijp.mums.ac.ir/article_16256_00fb4ed6934d4c4fe2ada1b8f59c5cf9.pdf
2021-06-01
13843
13851
10.22038/ijp.2020.49950.3985
Children
Education
Family
readmission
Quality of life
Nephrotic syndrome
Mehdi
Rezaei Nejad
m.rezaie11@gmail.com
1
Nursing and Midwifery College, Zahedan University of Medical Sciences, Iran.
AUTHOR
Alia
Jalalodini
a_jalalodini@yahoo.com
2
Pediatric Department, Community Nursing Research Center, Nursing and Midwifery College, Zahedan University of Medical Sciences, Iran.
LEAD_AUTHOR
Mahnaz
Ghaljeh
ghaljeh.m@gmail.com
3
Community Nursing Research Center, Zahedan University of Medical Sciences, Nursing and Midwifery College, Zahedan University of Medical Sciences, Iran.
AUTHOR
Ali
Navidian
alinavidian@gmail.com
4
Department of Counseling, Pregnancy Health Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
AUTHOR
Simin
Sadeghi-Bojd
sadeghi.s@yahoo.com
5
Pediatric Nephrologist, Children And Adolescent Health Research Center Zahedan University of Medical Sciences, Zahedan , Iran.
AUTHOR
ORIGINAL_ARTICLE
Tyrosinemia Type III: A Case Report with a Seven Years Follow-up
Hereditary tyrosinemia type III (OMIM 276710) is a rare inborn error of tyrosine metabolism caused by the deficiency of 4-hydroxyphenylpyruvate dioxygenase (HPD). This metabolic statement is transmitted in an autosomal recessive trait and hitherto about 18 cases presenting with this disease have been reported in the literature. Because of the low prevalence of the disease, the clinical phenotype remains variable and unclear, but the main symptoms are mostly related to the high concentrations of tyrosine and phenolic metabolites, namely mental retardation, ataxia, and seizures. We described the clinical, biochemical, and molecular characteristics of an Iranian female patient with tyrosinemia type III and her 7-year follow-up plan. A novel variant of HPD (609695) mutation (c.759+1 G>A) was identified in a homozygous pattern. Despite not being compliant with the recommended diet, the patient continued to have normal neuropsychiatric development in the follow-up, which questions the efficacy of a low-tyrosine diet.
https://ijp.mums.ac.ir/article_17865_0212bdbce15c7596284ce269214d3c4b.pdf
2021-06-01
13853
13857
10.22038/ijp.2021.56791.4451
Child
HPD gene
Tyrosinemia type III
Tyrosine metabolism
Saba
Vakili
sabavk90@gmail.com
1
Department of Medical Genetics, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
AUTHOR
Mohammadreza
Emami
mr.emami1992@gmail.com
2
Department of Pediatric Endocrinology and Metabolism, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Moein
Mobini
mobinim891@gmail.com
3
Department of Pediatric Endocrinology and Metabolism, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Rahim
Vakili
vakilir@mums.ac.ir
4
Department of Pediatric Endocrinology and Metabolism, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Role of Food Allergy in Development of Different Levels of Asthma Severity in Childhood
Background
Various risk factors, including previous history of food allergy, may play an important role in predicting the development and the outcome of asthma in children. This study aims to assess the relationship of previous food allergy in infancy with asthma severity later in childhood.
Materials and Methods: Infants and children of up to 14 years of age referred to the Allergy Clinics of Azad University Hospitals in Tehran, Iran from October 2018 to October 2019 due to asthma were enrolled in this cross-sectional study. After confirming the diagnosis by a specialist physician and determining the level of severity, the patients’ caregivers were asked to fill out an eight-item researcher-made questionnaire. The questionnaire focused on family and the child’s history of allergy, specifically a previous history of clinically diagnosed food allergy.
Results: A total of 170 asthmatic patients with a mean age of 7.1±3 years were enrolled in the study. A meaningful relationship was found between food allergy and asthma (p < 0.001). Also, there was a significant relationship between having a history of food allergy in children with moderate and severe asthma compared to those with mild asthma (p<0.001). However, no such meaningful relationship was found when comparing moderate and severe asthma (p=0.6).
Conclusion
The findings suggested that food allergy in conjunction with a positive family history is a risk factor for persistent problematic asthma, which places patients at greater risk of morbidity. A history of previous food allergy was significantly associated with moderate to severe asthma compared to mild asthma.
https://ijp.mums.ac.ir/article_16860_b811314154313c5f71b75c6bb33fd930.pdf
2021-06-01
13859
13864
10.22038/ijp.2020.52493.4167
Asthma
Children
food allergy
Severity
Parnia
Poursadri
poursadriparnia@gmail.com
1
Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
Mahboubeh
Mansouri
mbmans65@gmail.com
2
Department of Allergy and Clinical Immunology, Mofid Children Hospital, Shahid Beheshti University of Medical Scienves, Tehran, Iran.
AUTHOR
Amirnezam
Mir
miramirnezam@gmail.com
3
Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
Seyedeh Niloofar
Hashemi
d.nhashemi92@yahoo.com
4
Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
AUTHOR
Seyed Karen
Hashemitari
karenhashemi@outlook.com
5
Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
AUTHOR
Sepideh
Darougar
sepidehdarougar@yahoo.com
6
Department of Pediatrics, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Evaluation of Neck Circumference as Potential Marker for Metabolic Syndrome in Children
Background: Metabolic syndrome (MetS) is complicated condition especially in pediatrics. For better MetS definition, marker discovery are interested. More accurate simple indices may be of value, such as neck circumference (NC). We investigated accuracy of NC for the diagnosis of MetS in adolescent girls. Materials and Methods: This cross-sectional study was conducted on schoolgirl who live in Mashhad and Sabzevar cities, Razavi Khorasan, Iran at 2018. The study sample comprised 988 girls with mean age 14.56 ±1.53 years old. The NC measured in site between mid-cervical spine and mid-anterior neck and enzymatic commercial kits measured biochemical analysis. The definitions of MetS included: IDF, NCEP-ATP III, and two modified NCEPs. Results: Often subjects are non-smoker, menstruated, and reside in Mashhad. The age, living location, and dwelling type showed the very weak association with NC. NC was significantly associated with WC and elevated TG. The highest (r= 0.275 (P= 0.0001), and lowest (r= 0.155 (p < 0.001) association were between NC and the DeFerranti's and IDF definitions, respectively. The odd ratios (CI 95%) estimated for the different definitions were as follows: IDF: 1.41 (1.18- 1.69), NCEP: 1.54 (1.31- 1.79), Cook's: 1.68 (1.37- 2.07), and DeFerranti's: 1.59 (1.40- 1.80). ROC analysis showed that the specificity ranged between 78.57 – 100.00% and sensitivity ranged between 62.10 – 78.22% of NC for the different definitions of MetS definitions. A NC of >31 cm estimated as cutoff for all studied definitions except Cook's definition. Conclusion: Besed on the results, NC should be considered as marker for central obesity and fat distribution in the diagnosis of MetS.
https://ijp.mums.ac.ir/article_16822_eba1daebaa068d54f25dc42c2f8652e7.pdf
2021-06-01
13865
13874
10.22038/ijp.2020.52029.4137
Children
Anthropometric Index
metabolic syndrome
Obesity
Mostafa
Fazeli
fazelim921@mums.ac.ir
1
Department of Medical Genetics and Molecular Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Mohammad
Mohammad-Zadeh
mohammdzadehm@mums.ac.ir
2
Cellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
AUTHOR
Zahra
Meshkat
meshkatz@mums.ac.ir
3
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Gordon
Ferns
g.ferns@sussex.ac.uk
4
Division of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex BN1 9PH, UK.
AUTHOR
Hamidreza
Bahrami-Taghanaki
bahramihr@mums.ac.ir
5
Chinese and Complementary Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
AUTHOR
Majid
Ghayour-Mobarhan
ghayourm@mums.ac.ir
6
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
LEAD_AUTHOR
ORIGINAL_ARTICLE
Comparison of CPP-ACP, Fluoride Varnish and Gel effects on enamel microhardness of permanent teeth: In-Vitro
Background Dental caries occurs due to the imbalance in the course of demineralization-remineralization in favor of demineralization. With remineralization, some signs of halted progression could be observed in the primary stages. The aim of this study is to in-vitro investigation of the effect of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), fluoride varnish, and fluoride gel on the microhardness of the enamel of permanent teeth. Materials and Methods: In this in vitro study, 344 specimens prepared from human premolars were randomly divided into four groups (n=86 specimens in each group). After preparing the specimens, the initial enamel value was first evaluated by Vickers microhardness technique. The specimens were immersed in a demineralizing solution and then treated with remineralizing compounds (I. Control, II. Fluoride varnish, III. Fluoride gel and IV. CPP-ACP). Microhardness values were re-measured at the end of demineralization and remineralization stages. The data were analyzed using SPSS software (version 16.0). Results: The results of the present study indicated a statistically significant difference in all groups in terms of initial enamel microhardness (0.288 ± 42.77), remineralization (0.213 ± 26.89), and demineralization values (0.167 ± 63.87) (p <0.001). Besides, there was a statistically significant difference in different groups in terms of remineralization values (p <0.001). In other words, the mean microhardness was 241.21 ±15.60 in Group III, 221.12 ± 75.69 in Group II, 211.16 ± 43.04 in Group IV, and 178.21 ± 63.9 in group- I. Conclusion All remineralizing compounds resulted in enhanced microhardness of the enamel. Nevertheless, the fluoride-containing products showed greater potential in improving the level of microhardness and strength of the teeth compared to the compounds containing CPP-ACP.
https://ijp.mums.ac.ir/article_17537_1f1845b4b599c771c4d5b995d07f10ce.pdf
2021-06-01
13875
13886
10.22038/ijp.2021.54990.4358
CPP-ACP
Fluoride
microhardness
tooth enamel
Remineralization
Bahram
Akbari
aidazar@yahoo.com
1
Dentistry Student, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
AUTHOR
Haleh
Hali
h.hali.md@gmail.com
2
Assistant Professor, Pediatrics Department, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
LEAD_AUTHOR
Abbas
Mesgarani
a.mesgarani@gmail.com
3
Associate Professor, Endodontics Department, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.
AUTHOR
Mahmood
Moosazadeh
mmoosazadeh1351@gmail.com
4
Assistant Professor, Research Center for Health Sciences, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
AUTHOR