TY - JOUR ID - 20805 TI - The maternal and neonatal outcomes of pregnant women with definite COVID-19 JO - International Journal of Pediatrics JA - IJP LA - en SN - 2345-5047 AU - Shirazi, Mahboobeh AU - Najjari, Parisa AU - Jafarieh, Arash AU - Golshahi, Fatemeh AU - Sahebdel, Behrokh AU - Shirazi, Mahmoud AU - khazaeian, Safoura AU - Saeedi, Sania AU - Mofidifar, Yalda AU - Feizabad, Elham AU - Saeedi, Sara AD - Maternal, Fetal and Neonatal Research Center, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Perinatology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Anesthesiology, School of Medicine, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Department of Perinatology, Yas Hospital, Tehran University of Medical Sciences, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran. AD - Faculty of Educational and Psychology, Department Of Psychology, University Of Sistan and Baluchestan, Sistan and Baluchestan, Iran AD - Obstetrics and Gynecology Department, Pregnancy Health Research Center, Ali IbneAbitaleb Hospital, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran AD - Microbiology student of Shahid Beheshti University of Medical Sciences, Tehran, Iran Y1 - 2022 PY - 2022 VL - 10 IS - 10 SP - 16803 EP - 16810 KW - COVID-19 KW - pregnancy KW - Pregnancy trimesters KW - Morbidity KW - Mortality DO - 10.22038/ijp.2022.65843.4962 N2 - Background: This study aimed to assess the symptoms and clinical laboratory data of pregnant women with COVID-19 in their second or third trimester of pregnancy as well as their maternal and neonatal outcomes. Methods: This retrospective observational study was conducted on 177 pregnant women with COVID-19 who were admitted to Yas hospital (affiliated with Tehran University of Medical Sciences), and Ali-ibn-Abi-Talib hospital (affiliated with Zahedan University of Medical Sciences). Results: There was significant higher complaints including fever (p-value=0.015), cough (p-value=0.028), fatigue (p-value=0.002), dyspnea (p-value=0.022), and lower hemoglobin level (p-value=0.009) in patients who were in their third trimester compared to those who were in their second trimester. 9.6% (n=17) of the patients had severe disease and needed ICU admission. There was a significant variation regarding gestational age (p-value=0.022) in pregnant women admitted to ICU compared to the other ones. During the study, delivery happened in 108 (61%) pregnant women. Fetal distress following meconium deification (p-value=0.041), need to MGSO4 (p-value=0.001), IUFD (p-value=0.006), need for blood transfusion (p-value=0.004), and neonatal death (p-value<0.001) were significantly higher in patients who needed ICU admission. Conclusion: Higher gestational weeks are the main risk factor for severe COVID-19 disease. Although vertical transmission is rare; due to the higher risk of perinatal outcomes, the delivery should be done in a center with a NICU department. UR - https://ijp.mums.ac.ir/article_20805.html L1 - https://ijp.mums.ac.ir/article_20805_01c8199c69c7ffac44432823d49187f8.pdf ER -