TY - JOUR ID - 6991 TI - Effects of Iron in Neonates and Young Infants: a Review JO - International Journal of Pediatrics JA - IJP LA - en SN - 2345-5047 AU - Pacifici, Gian Maria AD - Via San Andrea 32, 56127 Pisa, Italy. Y1 - 2016 PY - 2016 VL - 4 IS - 7 SP - 2256 EP - 2271 KW - Anemia KW - effects KW - Infant KW - Iron KW - neonate DO - 10.22038/ijp.2016.6991 N2 - Iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. Iron is absorbed by the duodenum and requires an acidic environment for optimal absorption. Iron is found for 70% in erythrocytes, and 30% in storage, and a small amount in myoglobin and cytochromes. Iron supplementation reduces anemia in breastfed infants and increases in significant dose-dependent effects hemoglobin and ferritin levels, transferrin saturation, mean cell volume, and transferrin receptor levels. The prevalence of iron deficiency at 6 months of age is 36% in the placebo, 8.2% after 1 mg/kg per day, and 3.8% after 2 mg/kg per day iron (p UR - https://ijp.mums.ac.ir/article_6991.html L1 - https://ijp.mums.ac.ir/article_6991_0334cb4ec696b917ae8e62b33105b936.pdf ER -