TY - JOUR ID - 7316 TI - Association of Body Mass Index with Asthma Severity and Pulmonary Function among Asthmatic Children JO - International Journal of Pediatrics JA - IJP LA - en SN - 2345-5047 AU - Nasiri Kalmarzi, Rasuol AU - Hamedi, Razaq AU - Nasirian, Reza AU - Farsani, Masoud AU - Kashefi, Hajar AU - Khalafi, Behzad AU - Kooti, Wesam AD - Cellular and Molecular Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran AD - Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. AD - Department of Laboratory Science, School of Paramedical, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. AD - Shahid Chamran University, Ahvaz, Iran AD - Students Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran. Y1 - 2016 PY - 2016 VL - 4 IS - 9 SP - 3551 EP - 3559 KW - Asthma KW - Body mass index KW - Children KW - Pulmonary function DO - 10.22038/ijp.2016.7316 N2 - Background Asthma is a chronic inflammatory disease in respiratory system and obesity is another inflammatory disease which incidence rate is increasing. Although, many studies have been conducted on severity of asthma and its relationship with obesity, but different results have been obtained. This study aimed to determine a relationship between asthma severity, Body Mass Index (BMI) and pulmonary function in Kurdistan province, Iran. Materials and Methods: In this cross sectional study 90 asthmatic patients referred to referral hospital in Kurdistan, North West of Iran, were selected by simple random method. BMI was calculated by dividing weight by height.Pulmonary Function Test (PFT) and bronchial-stimulation-test were used for confirmation and investigation of asthma severity. Data were analyzed using SPSS-15 and Chi-square and spearman correlation coefficient tests. Results: Relationship between BMI and severity of asthma (mild, medium and severe) was evaluated, there was a relationship and positive relationship between them (P<0.05, r=0.23). There was a significant difference between spirometry indices in different levels of BMI variable (P<0.05). There was no significant relation between Forced expiratory volume in 1st second/Forced Vital Capacity (FEV1/FVC) and waist size (P>0.05), but there was a significant and inverse correlation between waist size and other parameters such as (FEV1, FVC and FEF25-75) (P<0.05). Furthermore, there was a significant and inverse correlation between spirometry indices and Waist-Hip ratio (WHR) (P<0.05) Conclusion It seems that attention to BMI in people with pulmonary diseases including asthma can help improve clinical and physiological conditions of the person. UR - https://ijp.mums.ac.ir/article_7316.html L1 - https://ijp.mums.ac.ir/article_7316_3a98e3a42b2c99ac21ccd82c84b1d5f1.pdf ER -