Document Type : case report

Authors

1 Pathology department, Faculty of Medicine, Mansoura, Egypt &Faculty of Medicine, Horus University in Egypt (HUE), Damietta El-Gadeeda, Damietta, Egypt.

2 Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

3 Pathology Department, Faculty of Medicine, Mansoura University, Egypt

4 Diagnostic and Interventional Radiology department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

5 Pediatrics department, Hematology/Oncology and Bone Marrow Transplantation unit, Faculty of Medicine, Mansoura University, Mansoura, Egypt. & Mansoura Research Center for Cord Stem Cells (MARC-CSC), Faculty of Medicine, Mansoura

Abstract

Introduction: Pediatric malignant presacral lesions are most often germ cell tumors notably sacrococcygeal teratoma, however, diagnosing neuroblastoma at this site is an unusual occurrence. Case presentation: We report a 5-month-old infant presented with a presacral mass misinterpreted as Altman type IV sacrococcygeal teratoma. Upon complete surgical resection, histopathological examination and immunohistochemistry for neuronal markers confirmed the diagnosis of poorly differentiated neuroblastoma and excluded the possibility of teratoma or alternate differential diagnoses. Unfavorable category was incited due to high mitosis-karyorrhexis and Ki-67 indices. Conclusions: Neuroblastoma should be considered in the differential diagnosis for infantile presacral masses. Evaluating infantile intra-pelvic masses necessitates a multidisciplinary approach.

Keywords