International Journal of Pediatrics

Growth Assessment and Vitamin D Level in Egyptian Juvenile Idiopathic Arthritis Patients

Rasha Abdel-magied; Gihan Omar; Sheren Maher

Volume 7, Issue 8 , August 2019, , Pages 9987-9995

https://doi.org/10.22038/ijp.2019.41070.3460

Abstract

Background Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases in childhood and is frequently associated with growth retardation. Vitamin D is critical ... Read More

Subclinical Atherosclerosis in Children with Rheumatologic Diseases in Minia Children University Hospital, Egypt

Sheren Maher; Moustafa Abdel Raheem; Hend Moness

Volume 7, Issue 3 , March 2019, , Pages 9159-9167

https://doi.org/10.22038/ijp.2018.36402.3174

Abstract

Background: Patients with rheumatologic diseases have higher rates of cardiovascular disease. Accelerated atherosclerosis and early coronary artery disease have become important causes ... Read More Background: Patients with rheumatologic diseases have higher rates of cardiovascular disease. Accelerated atherosclerosis and early coronary artery disease have become important causes of death and hospitalization in those patients which may be attributed to metabolic changes in lipids. We aimed to clarify the cardiovascular risk in children with juvenile idiopathic arthritis (JRA), and systemic lupus erythematosus (SLE), and its relation to lipid profile and disease activity index. Materials and Methods In this cross sectional comparative study which was done in Minia Children University Hospital, Egypt, we measured lipid profile (cholesterol, triglycerides, low and high density lipoproteins), erythrocyte sedimentation rate, and C-reactive protein in 15 patients with JRA (group1), and 15 patients with SLE (group 2), and in 30 healthy children as controls (group 3). Results Results showed that there were no significant differences between group 1 (JRA) patients, and controls in total cholesterol, triglycerides, low and high density lipoproteins, but there were high statistically significant differences between group 2 (SLE) patients, and controls in total cholesterol, triglycerides, low density lipoproteins (p<0.001), and in high density lipoproteins (p<0.008).There were positive significant correlations between disease activity index in JRA patients with total cholesterol (r=0.633, p=0.011), triglycerides (r=0.523, p=0.046), and low density lipoproteins (r=0.548, p=0.034). Also, positive significant correlations between disease activity index in SLE patients with total cholesterol (r=0.579, p=0.024), triglycerides (r=0.559, p=0.030), and low-density lipoprotein (r=0.533, p=0.041). Conclusion Children with rheumatologic diseases can be at high risk of arthrosclerosis and cardiovascular events due to lipid profile change which may be associated with subclinical arthrosclerosis, so continuous monitoring of lipid profile can decrease mortality and co-morbidity.

Assessment of Health Related Quality of Life (HRQL) in Egyptian Children with Rheumatic Diseases; Its Relation to Disease Activity and Functional Disability

Sheren Maher; Rasha Abdel-magied

Volume 7, Issue 1 , January 2019, , Pages 8795-8803

https://doi.org/10.22038/ijp.2018.34033.2999

Abstract

Background Many pediatric rheumatic diseases persist into adulthood, with negative squeal from the disease or its treatment. We aimed to assess health related quality of life in a group ... Read More

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Author = Sheren Maher

Growth Assessment and Vitamin D Level in Egyptian Juvenile Idiopathic Arthritis Patients

Abstract

Subclinical Atherosclerosis in Children with Rheumatologic Diseases in Minia Children University Hospital, Egypt

Abstract

Assessment of Health Related Quality of Life (HRQL) in Egyptian Children with Rheumatic Diseases; Its Relation to Disease Activity and Functional Disability

Abstract