International Journal of Pediatrics

Comparison of Postoperative Pain in Two Groups of Children with Bone Fractures Receiving Pethidine and Paracetamol in Kerman Bahonar Hospital: A Clinical Trial Study

Ali Rokni; Majid Sezavar; Abdolmajid Eslahtalab; Mohammad Mobin Mirimoghaddam; Sara Behzadfar; Mohammad Mahdi Jalalpour; Ali Pour Amiri

Volume 8, Issue 10 , October 2020, , Pages 12213-12221

https://doi.org/10.22038/ijp.2020.51516.4094

Abstract

Background Paracetamol and Pethidine are two prevailing analgesics prescribed for postoperative orthopedic patients, each having different side effects and impacts on fracture healing. ... Read More

The Efficacy of Meperidine for Pain Management in Orthopedic, Dental, and General Surgery in Children: A Review Study

Ali Rokni; Abdolmajid Eslahtalab; Reza Ahmadi; Majid Sezavar; Masoud Gharaei Jomehei; Omolbanin Heydari; Fatemeh Vafi sani; Neda Asadi

Volume 8, Issue 10 , October 2020, , Pages 12305-12316

https://doi.org/10.22038/ijp.2020.51608.4101

Abstract

Background: The present study aimed to assess the efficacy of Meperidine for pain relief in children after orthopedic, abdominal surgery, and laceration repair. Materials and Methods: ... Read More

Effect of Gastric Acid Suppressant Prophylaxis on Incidence of Gastrointestinal Bleeding in Pediatric Intensive Care Unit

Tahoora Abdollahi; Alireza Sabzevari; Ali Khakshour; Alireza Ataiee Nakhaie; Majid Sezavar; Toktam Etezadie; hamidreza kianifar; Seyed Ali Jafari; Mohammad Ali Kiani

Volume 4, Issue 11 , November 2016, , Pages 3917-3924

https://doi.org/10.22038/ijp.2016.7315

Abstract

Background: Critically ill children admitted to pediatric intensive care unit (PICU) are at increased risk of gastrointestinal bleeding due to stress related mucosal injury. Reducing ... Read More Background: Critically ill children admitted to pediatric intensive care unit (PICU) are at increased risk of gastrointestinal bleeding due to stress related mucosal injury. Reducing gastric acid by acid suppressant medication is the accepted prophylaxis treatment, but there is not any definitive guideline for using prophylaxis in PICU patients. The present study aimed to assess the effect of Proton Pump Inhibitor (PPI) and H2 Blocker (H2B) prophylaxis on gastrointestinal bleeding in admitted patients of PICU, Mashhad- Iran.Materials and Methods: In this study, 100 patients admitted in PICU divided into two equal groups on the first day of admission. They received ranitidine or pantoprazole as prophylaxis of stress ulcer. Those patients who had history of gastrointestinal bleeding or coagulation disorder were excluded. 100 PICU patients who had not received prophylaxis during last 6 months retrospectively evaluated as control of the study. Data were collected as demographic characteristics, admission reason, definitive diagnosis, receiving corticosteroid and mechanical ventilation in each patient. Gastrointestinal bleeding (hematemesis, coffee ground aspirate, and melena) and clinically significant gastrointestinal bleeding were daily monitored. Data analyzed through descriptive statistical tests, Chi-square, logistic regression, t-test and using SPSS-16 software.Results: Among 204 patients (control group=105 and case group=99), incidence of gastrointestinal bleeding (GB) was 13.2% in which 6.9% of cases presented with clinically significant gastrointestinal bleeding (CSGB). Loss of consciousness and respiratory distress were the main reason of admission. There was no significant differences between the incidence of (GB) and (CSGB) in experimental and control groups (P>0.05) as well as ranitidine and pantoprazole prophylaxis (P>0.05). Significant risk factors of (GB) were mechanical ventilation and loss of consciousness and corticosteroid therapy.Conclusion: There is ambiguity about probable benefits of gastrointestinal bleeding prophylaxis in critically ill children. We proposed that prophylaxis should prescribe in patients with two or more risk factors of gastrointestinal bleeding.

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Author = Majid Sezavar

Comparison of Postoperative Pain in Two Groups of Children with Bone Fractures Receiving Pethidine and Paracetamol in Kerman Bahonar Hospital: A Clinical Trial Study

Abstract

The Efficacy of Meperidine for Pain Management in Orthopedic, Dental, and General Surgery in Children: A Review Study

Abstract

Effect of Gastric Acid Suppressant Prophylaxis on Incidence of Gastrointestinal Bleeding in Pediatric Intensive Care Unit

Abstract