Clinical Pharmacology of the Antimalarial Chloroquine in Children and Their Mothers
Clinical Pharmacology of the Antimalarial Chloroquine in Children and Their Mothers

Gian Maria Pacifici

Volume 6, Issue 6 , June 2018, , Pages 7733-7758

https://doi.org/10.22038/ijp.2018.30912.2727

Abstract
  Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and Plasmodium knowlesi are the parasites that infect humans. Plasmodium falciparum and Plasmodium vivax ...  Read More
Clinical Pharmacology of the Antimalarial Quinine in Children
Clinical Pharmacology of the Antimalarial Quinine in Children

Gian Maria Pacifici

Volume 6, Issue 4 , April 2018, , Pages 7451-7465

https://doi.org/10.22038/ijp.2018.30206.2658

Abstract
  Quinine is the best studied drug for treating severe malaria in very young children. Quinine may be administered in pregnancy and, at therapeutic doses, malformations have not been ...  Read More
Treatment of Malaria Parasitaemia in Infants and their Mothers
Treatment of Malaria Parasitaemia in Infants and their Mothers

Gian Maria Pacifici

Volume 6, Issue 3 , March 2018, , Pages 7311-7343

https://doi.org/10.22038/ijp.2018.29670.2607

Abstract
  Malaria is an infection sustained by three parasites namely: Plasmodium falciparum, Plasmodium vivax, and Plasmodium ovale. Plasmodium falciparum is the most common and virulent parasite. ...  Read More
Clinical Pharmacology of Ampicillin in Neonates and Infants: Effects and Pharmacokinetics
Clinical Pharmacology of Ampicillin in Neonates and Infants: Effects and Pharmacokinetics

Gian Maria Pacifici

Volume 5, Issue 12 , December 2017, , Pages 6383-6410

https://doi.org/10.22038/ijp.2017.26942.2320

Abstract
  Ampicillin is a bactericidal antibiotic, it penetrates into the bacterial wall better than penicillin G and is active against gram-negative bacteria that are resistant to penicillin ...  Read More
Clinical Pharmacology of Ceftriaxone in Neonates and Infants: Effects and Pharmacokinetics
Clinical Pharmacology of Ceftriaxone in Neonates and Infants: Effects and Pharmacokinetics

Gian Maria Pacifici; Giovanna Marchini

Volume 5, Issue 9 , September 2017, , Pages 5751-5778

https://doi.org/10.22038/ijp.2017.25371.2155

Abstract
  Ceftriaxone is a versatile and useful "third-generation" cephalosporin that needs to be administered once-daily. Ceftriaxone is a β-lactamase-resistant cephalosporin. It is active ...  Read More
Clinical Pharmacology of Ciprofloxacin in Neonates: Effects and Pharmacokinetics
Clinical Pharmacology of Ciprofloxacin in Neonates: Effects and Pharmacokinetics

Gian Maria Pacifici; Giovanna Marchini

Volume 5, Issue 6 , June 2017, , Pages 5023-5041

https://doi.org/10.22038/ijp.2017.23193.1952

Abstract
  Ciprofloxacin is the most commonly used fluoroquinolone. Ciprofloxacin is prescribed for 1 in 44 Americans. Ciprofloxacin is a broad-spectrum bactericidal antibiotic, effective against ...  Read More
Clinical Pharmacology of Ceftazidime in Neonates: Effects and Pharmacokinetics
Clinical Pharmacology of Ceftazidime in Neonates: Effects and Pharmacokinetics

Gian Maria Pacifici; Giovanna Marchini

Volume 5, Issue 5 , May 2017, , Pages 4803-4819

https://doi.org/10.22038/ijp.2017.22928.1920

Abstract
  Ceftazidime is a valuable third-generation bactericidal cephalosporin. Ceftazidime inhibits the biosynthesis of bacterial cell peptidoglycan, causing inhibition of bacterial growth ...  Read More
Clinical Pharmacology of Cefepime in Infants and Children
Clinical Pharmacology of Cefepime in Infants and Children

Gian Maria Pacifici; Giovanna Marchini

Volume 5, Issue 4 , April 2017, , Pages 4723-4740

https://doi.org/10.22038/ijp.2017.22763.1907

Abstract
  Cefepime is a fourth-generation cephalosporin which is approved in Europe and in the USA. Food and Drug Administration (FDA) approves cefepime in the treatment of febrile neutropenia. ...  Read More
Clinical Pharmacokinetics of Gentamicin in Neonates
Clinical Pharmacokinetics of Gentamicin in Neonates

Gian Maria Pacifici; Gian Maria Pacifici

Volume 5, Issue 3 , March 2017, , Pages 4575-4599

https://doi.org/10.22038/ijp.2017.22354.1869

Abstract
  Gentamicin is a bactericidal aminoglycoside antibiotic, it inhibits the protein synthesis. Gentamicin is active against the majority of aerobic gram-negative bacilli such as Pseudomonas, ...  Read More
The Effects and Pharmacokinetics of Acyclovir in Neonates
The Effects and Pharmacokinetics of Acyclovir in Neonates

Gian Maria Pacifici

Volume 4, Issue 12 , December 2016, , Pages 4099-4115

https://doi.org/10.22038/ijp.2016.8002

Abstract
      Acyclovir (9-[2-hydroxyethoxymethyl] guanine) is an acyclic nucleoside analogue of guanosine which is a potent and selective antiviral agent. Acycloviris converted to ...  Read More
Clinical Pharmacology of Teicoplanin in Neonates: Effects and Pharmacokinetics
Clinical Pharmacology of Teicoplanin in Neonates: Effects and Pharmacokinetics

Gian Maria Pacifici

Volume 4, Issue 10 , October 2016, , Pages 3669-3684

https://doi.org/10.22038/ijp.2016.7629

Abstract
  Teicoplanin is a glycoside antibiotic which consists of five closely related glycopeptide antibiotics with similar antibacterial properties to vancomycin that were first isolated in ...  Read More