Infectious Diseases Research Center (IDRC), Department of Pediatric, School of Medicine, Arak University of Medical Sciences, Arak, Iran.


Dysentery is described as a diarrhea with visible blood in the feces. In some regions of world, resistance to antibiotic was reported. Therefore, it is very important to use a safer treatment for this disease. We aimed to survey the efficacy of Golden Immunstim drug on improvement of abdominal cramp, diarrhea, vomiting, and fever in dysenteric patients.
Materials and Methods
This study is a randomized clinical trial, conducted on 100 children with dysentery who visited the outpatient Pediatric Clinic of Amirkabir Hospital in Arak, Iran. Patients were randomly divided into two equal intervention and control groups (n=50).The intervention group received antibiotics (ceftriaxone with a dose of 50mg/kg twice  per day [BID] until the symptoms of the patient improve and continue with oral Cefixime until the completion of the 5-day treatment period), and Golden Immunstim (two capsules per day for three days), and the control group only received routine antibiotics. The researchers assessed participants on days 3, 7 and 14. Data were analyzed using SPSS 23.0 software.
On days 3, 7, and 14 abdominal cramp was in 12%, 2%, 0% in intervention group, respectively and was 16%, 0%, 0% in control group (p>0.05); Diarrhea 8%, 2%, 0 % in intervention group, and 8%, 0%, 0%  in control group (p>0.05). Vomiting was in 2%, 0%, 0% of intervention group and 0%, 0%, 0% of control group (p>0.05); Fever was in 2%, 0%, 0% of intervention group and 6%, 0%, 0% of control group (p>0.05).
According to the results of this study, it can be concluded that Golden Immunstim has no effect on dysentery symptoms.