1 Resident of Pediatrics, Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran.

2 Pediatrics Center of Excellence, Children Medical Hospital, Tehran University of Medical Science, Tehran, Iran.

3 Research Center for Addiction and Risky Behaviors, Iran University of Medical Sciences, Tehran, Iran.

4 Faculty Member of Paramedical School, Ilam University of Medical Science, Ilam, Iran.

5 Fellowship of Pediatrics Anesthesiology, Department of Anesthesiology, Mashhad University of Medical Sciences, Mashhad, Iran.

6 Abnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran.

7 Medical student, Student research committee, Mazandaran university of medical science ,sari, Iran

8 Student Research Committee. Mazandaran University of Medical Sciences. Sari, Mazandaran, Iran.

9 Faculty of Humanities, Damghan University, Damghan, Iran.

10 Department of Nursing and Midwifery, Razi School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran.

11 Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.


Background: Sleep disturbances among child patients are a commonly reported problem. We aimed to review the effectiveness of aromatherapy on sleep disorders of children and infants.
Materials and Methods:  This review was conducted with a systematic search of electronic resources in English such as Medline (via PubMed), Scopus, Web of Science, Cochrane Library, and EMBASE, with no time limit from inception up to February 2019; using the following keywords alone or in combination: (Aromatherapy OR Smell OR Olfactory OR Essential oil) AND (Sleep Disorders OR Sleep OR Sleep Paralysis OR Sleep Arousal Disorders) AND (Children OR Infant OR Baby OR Neonate OR Pediatric).
Results: Four studies were included in the review. In the first study, a comparison of the nights with and without aromatherapy showed no significant difference regarding length of time the children were asleep, sleep onset time and number of interruptions during the night. In the second study, aromatherapy with Rosa damascena essential oil significantly improved sleep quality parameters in children except with daytime sleeping (p=0.059). In the third study, a significant decrease was observed in the sleep quality score in children with acute lymphoblastic leukemia in aromatherapy with oil of orange than in the controls (p<0.05). In the fourth study, the infants in the Lavender bath oil group spend  more time in deep sleep and less time crying prior to sleep onset than in the control group (p<0.05).
Conclusion: Aromatherapy with Lavender and Rosa damascena essential oil and orange oil can improve group sleep quality, deep sleep and time crying prior to sleep onset. However, it was not effectiveregarding sleep disorder in children with autism.


  1. Ayazi R, Mirzakhani N, Rajaei S, Khalatbari J, Gol SVMC. Sleep in children with autistic spectrum disorder. J Rehabil Med. 2017;6(1):226-33.
  2. Shapiro CM, Griesel RD, Bartel PR, Jooste PL. Sleep patterns afted graded exercise. Journal of Applied Physiology. 1975;39(2):187-90.
  3. Giri P, Baviskar M, Phalke D. Study of sleep habits and sleep problems among medical students of Pravara Institute of Medical Sciences Loni, Western Maharashtra, India. Annals of medical and health sciences research. 2013;3(1):51-4.
  4. Ozgoli G, Sheikhan Z, Soleimani F, Mirzaee S, Janatiataee P, Ziaie T, et al. Prevalence of Sleep Disorders and its Related Factors among Preschool Children. Journal of Health and Care. 2015;17(3):198-206.
  5. Raymond I, Nielsen TA, Lavigne G, Manzini C, Choinière M. Quality of sleep and its daily relationship to pain intensity in hospitalized adult burn patients. PAIN®. 2001;92(3):381-8.
  6. alijani ranani h, noruzi zamenjani m, amin asnafi a, Latifi M. The effect of aromatherapy with orange essential oils on sleep quality in the school-age children whit ALL. complementary Medicine Journal. 2015;5(1):1113-22.
  7. Hassanzadeh M, Sajadi S, Farsi Z. Comparison of the Effect of Sedamin Capsule (Valerian) and Inhaling Lavender Essence on Sleep Quality of Hospitalized Patients at the Cardiac Care UniT. MCS 2018, 4(3): 187-197.
  8. alijani ranani H, noruzi zamenjani M, amin asnafi A, Latifi M. The effect of aromatherapy with orange essential oils on sleep quality in the school-age children whit ALL. cmja. 2015; 5 (1) :1113-1122
  9. "Aromatherapy". Better Health Channel. Archived from the original on 27 February 2012. Retrieved 14 August 2014.
  10. Kuriyama, Hiroko; Watanabe, Satoko; Nakaya, Takaaki; Shigemori, Ichiro; Kita, Masakazu; Yoshida, Noriko; Masaki, Daiki; Tadai, Toshiaki; Ozasa, Kotaro; Fukui, Kenji; Imanishi, Jiro (2005). "Immunological and Psychological Benefits of Aromatherapy Massage". Evidence-Based Complementary and Alternative Medicine. 2 (2): 179–184. doi:1093/ecam/neh087PMC 1142199PMID 15937558.
  11. "Alternative therapies and cancer - Cancer Information". Macmillan Cancer Support. 17 April 2014. Archived from the original on 3 October 2014. Retrieved 21 August 2019.
  12. University of Maryland Medical Center - Aromatherapy". University of Maryland Medical Center. University of Maryland Medical Center. Retrieved 13 August 2014.

13. The P.I.C.O. Model for Clinical Questions. Available at: 

  1. Williams TI. Evaluating effects of aromatherapy massage on sleep in children with autism: a pilot study. Evidence-Based Complementary and Alternative Medicine. 2006;3(3):373-7.
  2. Keyhanmehr AS, Movahhed M, Sahranavard S, Gachkar L, Hamdieh M, Nikfarjad H. The effect of aromatherapy with rosa damascena essential oil on sleep quality in children. Research Journal of Pharmacognosy. 2018;5(1):41-6.
  3. Alijani ranani H, noruzi zamenjani M, amin asnafi A, Latifi M. The effect of aromatherapy with orange essential oils on sleep quality in the school-age children whit ALL. cmja. 2015; 5 (1) :1113-22.


  1. Field T, Field T, Cullen C, Largie S, Diego M, Schanberg S, et al. Lavender bath oil reduces stress and crying and enhances sleep in very young infants. Early human development. 2008;84(6):399-401.
  2. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled clinical trials. 1996;17(1):1-12.
  3. Kianpour M, Moshirenia F, Kheirabadi G, Asghari G, Dehghani A, Dehghani-Tafti A. The effects of inhalation aromatherapy with rose and lavender at week 38 and postpartum period on postpartum depression in high-risk women referred to selected health centers of Yazd, Iran in 2015. Iranian journal of nursing and midwifery research. 2018;23(5):395.
  4. Afkham Ebrahimi A, Bandi G, Salehi M, Tafti K, Vakili Y, Farsi A. Sleep parameters and the factors affecting the quality of sleep in patients attending selected clinics of Rasoul-e-Akram hospital. Razi Journal of Medical Sciences. 2008;15:31-8.
  5. Galicia-Connolly E, Adams D, Bateman J, Dagenais S, Clifford T, Baydala L, et al. CAM use in pediatric neurology: an exploration of concurrent use with conventional medicine. PloS one. 2014;9(4):e94078.
  6. Cuomo BM, Vaz S, Lee EAL, Thompson C, Rogerson JM, Falkmer T. Effectiveness of sleep‐based interventions for children with autism spectrum disorder: a meta‐synthesis. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2017;37(5):555-78.
  7. Tilford JM, Payakachat N, Kuhlthau KA, Pyne JM, Kovacs E, Bellando J, et al. Treatment for sleep problems in children with autism and caregiver spillover effects. Journal of autism and developmental disorders. 2015;45(11):3613-23.