Authors

1 Pediatric Department, Faculty of Medicine, Helwan University, Egypt.

2 Radiodiagnosis Department, Faculty of Medicine, Helwan University, Egypt.

3 Clinical Pathology Department, Faculty of Medicine, Helwan University, Egypt

4 Pediatric Department, Faculty of Medicine, Helwan University, Egypt

Abstract

Our study aimed to assess Carotid artery Intima-Media Thickness (CIMT) in a group of children with overweight/obesity as a good predictor for atherosclerosis.
We included 39 prepubertal children with Body Mass Indexes (BMI) above 85% for age and sex; 23% overweight, and 77% obese. Twenty matched non-obese healthy children were enrolled to compare CIMT results. About 44% of the cases had abnormal blood pressure, ~39% had dyslipidemia, and ~74% had an unhealthy metabolic state.
We observed higher CIMT in cases than controls, with no significant difference between overweight and obese status (at a confidence interval of 95% and P < 0.05). CIMT was positively associated with the BMI of the whole study group, and with HC and triglyceride in the children with obesity. CIMT was significantly higher among children with overweight/obesity than in average weight children, regardless of their metabolic status or blood pressure stage.

Keywords

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