Authors

1 Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

2 Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran

3 Clinical Research Development Unit of Children Educational and Treatment Center, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

This case report describes a 30-month-old child with primary pulmonary rhabdomyosarcoma with a congenital cystic adenomatoid malformation (CCAM). In the current literature, primary pulmonary neoplasms have been reported for similar cases. The tumor was located in the anterior-basal segment of the left lower lobe with a thin-walled cystic appearance and lobulated margins. A histology examination showed rhabdomyosarcoma origin with an embryonal subtype. Postoperative systemic chemotherapy was carried out. After a 6-month follow-up, the patient had no residual or recurrent disease.

Keywords

  1. Hancock BJ, Di Lorenzo M, Youssef S, Yazbeck S, Marcotte J-E, Collin P-P. Childhood primary pulmonary neoplasms. Journal of pediatric surgery. 1993; 28(9):1133-6.
  2. Doladzas T, Arvelakis A, Karavokiros IG, Gougou Die, Pikoulis E, Patsouris E, et al. Primary rhabdomyosarcoma of the lung arising over cystic pulmonary adenomatoid malformation. Pediatric hematology and oncology. 2005; 22(6):525-9.
  3. Murphy JJ, Blair GK, Fraser GC, Ashmore PG, LeBlanc JG, Sett SS, et al. Rhabdomyosarcoma arising within congenital pulmonary cysts: report of three cases. Journal of pediatric surgery. 1992; 27(10):1364-7.
  4. Choi JH, Ro JY. The 2020 WHO classification of tumors of soft tissue: selected changes and new entities. Advances in Anatomic Pathology. 2021; 28(1):44-58.
  5. Chi JG, Song YK. Diffuse striated muscle heteroplasia of the lung. An autopsy case. Archives of Pathology & Laboratory Medicine. 1982; 106(12):641-4.
  6. Fallon G, Schiller M, Kilman JW. Primary rhabdomyosarcoma of the bronchus. The Annals of Thoracic Surgery. 1971; 12(6):650-4.
  7. Hafiz B, Bamefleh H. Primary Pulmonary Alveolar Rhabdomyosarcoma in a Pediatric Patient: A Case Report with Literature Review. Cureus. 2022; 14(1).