Document Type : original article


1 Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran

2 Azadi Sqr., Vakilabad Blvd., Mashad Dental School, Orthodontic Dept.

3 Private Practice

4 Assistant professor of Department of Pediatric Surgery, School of Medicine, Azad University of Mashhad, Mashhad, Iran

5 Department of Oral and Maxillofacial Radiology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran

6 Assistant professor of Department of Physical Therapy , School of Paramedical Sciences, Mashhad University of Medical Sciences , Mashhad, Iran


Objective: The aim of this study was to investigate the efficacy of the low intensity pulsed ultrasound in reconstruction of the alveolar cleft area after autologous bone grafting.

Methods: In this study, 14 patients with unilateral or bilateral cleft lip and palate aged between 9 to 13 years, were selected. Seven of the patients received only the autologous bone graft and the seven others underwent alveolar bone graft and one week after transplantation were subjected to LIPUS waves for five minutes at a frequency of 1 MHz and 100 mW in the area of the graft for a period of five weeks (15 sessions). CBCT images were immediately taken after surgery and three months later. In CBCTs, bone mass was measured with two components of height and bone thickness and the quality was measured by evaluating the bone density by means of the Hounsfield Uniform (HU) mean.

Results: The mean changes of the sagittal thickness, sagittal height, and axial thickness before and after surgery, in contrast to the axial height and density, were less in the control group than the intervention group, but the differences were not significant for any of variables. In the intervention and control groups, mean values of the sagittal thickness, sagittal height, axial thickness, and axial height decreased significantly three months later than immediately after surgery, but the mean loss in density was not significant.

Conclusion: Ultrasound in repairing alveolar defect in patients with cleft palate has no significant effect on clinical success criteria.