Document Type : review article

Authors

1 Student research committee, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Diagnosis of the cystic lesion of the neck in pediatric cases is challenging for radiologists. There are different cystic lesions in the neck region that can present themselves in various parts of this area. Some lesions may lie in the middle parts and some in the lateral areas; however, some cystic defects can be present in every part of the neck. Sonography is the first modality for the assessment of the cases, along with history and physical examination. Sonography is nearly accessible and is not expensive; however, it depends on the expertise of the sonographer. We reviewed sonography findings of various cystic lesions in the neck region and reported the findings with this regard.

Keywords

  1. Ragesh K, Chana R, Varshney P, Naim M. Head and neck masses in children: A clinicopathological study. Indian Journal of Otolaryngology and Head and Neck Surgery. 2002; 54(4):268-71.
  2. Glickman A, Karlis V. Pediatric benign soft tissue oral and maxillofacial pathology. Oral and Maxillofacial Surgery Clinics. 2016; 28(1):1-10.
  3. Jackson DL. Evaluation and management of pediatric neck masses: an otolaryngology perspective. Physician Assistant Clinics. 2018; 3(2):245-69.
  4. Harish K. Neck dissections: radical to conservative. World journal of surgical oncology. 2005; 3(1):1-13.
  5. Юнусова Л, Аояма Т, Амануллаев Р, Ризаев Д, Икрамов Г, Сакамото Д, Халманов Б, Мамараджабов С. Sonography and magnetic resonance tomography in monitoring recurrent cysts lesions of the neck. In the Library. 2021; 21(2):131-4.
  6. Tahir A, Sankar V, Makura Z. Thyroglossal duct cyst carcinoma in child†. Journal of Surgical Case Reports. 2015; 2015(4).
  7. Salahuddin G, Islam MT, Huq MM, Mondal SK, Sobhan MA, Mondal DK. Sonographic evaluation of congenital cystic neck masses with histopathological correlation. Bangladesh Journal of Otorhinolaryngology. 2018; 24(1):68-78.
  8. Hussain A, Sajjad H. Anatomy, Head and Neck, Thyroid Thyroglossal Duct. 2020.
  9. Ross J, Manteghi A, Rethy K, Ding J, Chennupati SK. Thyroglossal duct cyst surgery: A ten-year single institution experience. International journal of pediatric otorhinolaryngology. 2017; 101:132-6.
  10. Thompson LD, Herrera HB, Lau SK. A clinicopathologic series of 685 thyroglossal duct remnant cysts. Head and neck pathology. 2016; 10(4):465-74.
  11. Amos J, Shermetaro C. Thyroglossal duct cyst. StatPearls [Internet]: StatPearls Publishing; 2021.
  12. Ahuja AT, King AD, King W, Metreweli C. Thyroglossal duct cysts: sonographic appearances in adults. American journal of neuroradiology. 1999; 20(4):579-82.
  13. Ahuja A, King A, Metreweli C. Sonographic evaluation of thyroglossal duct cysts in children. Clinical radiology. 2000; 55(10):770-4.
  14. Oyewumi M, Inarejos E, Greer ML, Hassouneh B, Campisi P, Forte V, J Propst E. Ultrasound to differentiate thyroglossal duct cysts and dermoid cysts in children. The Laryngoscope. 2015; 125(4):998-1003.
  15. Corvino A, Pignata S, Campanino MR, Corvino F, Giurazza F, Tafuri D, Pinto F, Catalano O. Thyroglossal duct cysts and site-specific differential diagnoses: imaging findings with emphasis on ultrasound assessment. Journal of Ultrasound. 2020; 23(2):139-49.
  16. Kutuya N, Kurosaki Y. Sonographic assessment of thyroglossal duct cysts in children. Journal of Ultrasound in Medicine. 2008; 27(8):1211-9.
  17. Choi HI, Choi YH, Cheon J-E, Kim WS, Kim I-O. Ultrasonographic features differentiating thyroglossal duct cysts from dermoid cysts. Ultrasonography. 2018; 37(1):71.
  18. Tokarz E, Gupta P, McGrath J, Szymanowski AR, Behar J, Behar P. Proposed ultrasound algorithm to differentiate thyroglossal duct and dermoid cysts. International Journal of Pediatric Otorhinolaryngology. 2021; 142:110624.
  19. Zander DA, Smoker WR. Imaging of ectopic thyroid tissue and thyroglossal duct cysts. Radiographics. 2014; 34(1):37-50.
  20. Holland A, Sparnon A, LeQuesne G. Thyroglossal duct cyst or ectopic thyroid gland? Journal of pediatrics and child health. 1997; 33(4):346-8.
  21. Pryor SG, Lewis JE, Weaver AL, Orvidas LJ. Pediatric dermoid cysts of the head and neck. Otolaryngology - Head and Neck Surgery. 2005; 132(6):938-42.
  22. Shareef S, Ettefagh L. Dermoid cyst. StatPearls [Internet]: StatPearls Publishing; 2021.
  23. Nakajima K, Korekawa A, Nakano H, Sawamura D. Subcutaneous dermoid cysts on the eyebrow and neck. Pediatric Dermatology. 2019; 36(6):999-1001.
  24. Choi JS, Bae YC, Lee JW, Kang GB. Dermoid cysts: epidemiology and diagnostic approach based on clinical experiences. Archives of Plastic Surgery. 2018; 45(06):512-6.
  25. Otigbah C, Thompson MO, Lowe DG, Setchell M. Mobile globules in benign cystic teratoma of the ovary. BJOG: An International Journal of Obstetrics & Gynaecology. 2000; 107(1):135-8.
  26. Zito PM, Scharf R. Epidermoid cyst. StatPearls [Internet]: StatPearls Publishing; 2021.
  27. Yasumoto M, Shibuya H, Gomi N, Kasuga T. Ultrasonographic appearance of dermoid and epidermoid cysts in the head and neck. Journal of clinical ultrasound. 1991; 19(8):455-61.
  28. Denison CM, Ward VL, Lester SC, DiPiro PJ, Smith DN, Meyer JE, Frenna TH. Epidermal inclusion cysts of the breast: three lesions with calcifications. Radiology. 1997; 204(2):493-6.
  29. Trinh CT, Nguyen CH, Khamsomphou V, Khamsomphou V, Tran TTT. Overview of epidermoid cyst. European journal of radiology open. 2019; 6:291-301.
  30. Olojede ACO, Ogundana OM, Emeka CI, Adewole RA, Emmanuel MM, Gbotolorun OM, et al. Plunging ranula: surgical management of case series and the literature review. Clinical case reports. 2018; 6(1):109.
  31. Carlini V, Calcaterra V, Pasqua N, Guazzotti M, Fusillo M, Pelizzo G. Plunging ranula in children: case report and literature review. Pediatric reports. 2016; 8(4):6576.
  32. Suresh BV, Vora SK. Huge plunging ranula. J Maxillofac Oral Surg. 2012; 11(4):487-90.
  33. de Visscher JGAM, van der Wal KGH, de Vogel PL. The plunging ranula: Pathogenesis, diagnosis and management. Journal of Cranio-Maxillofacial Surgery. 1989; 17(4):182-5.
  34. Valentino M, Quiligotti C, Carone L. Branchial cleft cyst. Journal of Ultrasound. 2013; 16(1):17-20.
  35. Allen SB, Jamal Z, Goldman J. Branchial cleft cysts. StatPearls [Internet]: StatPearls Publishing; 2021.
  36. Panchbhai A, Choudhary M. Branchial cleft cyst at an unusual location: a rare case with a brief review. Dentomaxillofacial Radiology. 2012; 41(8):696-702.
  37. Bluestone CD, Healy GB, Simons JP. Pediatric otolaryngology: PMPH-USA; 2014.
  38. Adams A, Mankad K, Offiah C, Childs L. Branchial cleft anomalies: a pictorial review of embryological development and spectrum of imaging findings. Insights into Imaging. 2016; 7(1):69-76.
  39. Lee H-J, Kim E-K, Hong S. Sonographic detection of intrathyroidal branchial cleft cyst: a case report. Korean journal of radiology. 2006; 7(2):149-51.
  40. Sturm JJ, Dedhia K, Chi DH. Diagnosis and management of cervical thymic cysts in children. Cureus. 2017; 9(1).
  41. Bockman DE. Development of the thymus. Microscopy research and technique. 1997; 38(3):209-15.
  42. Shenoy V, Kamath MP, Hegde MC, Rao Aroor R, Maller VV. Cervical thymic cyst: a rare differential diagnosis in lateral neck swelling. Case reports in otolaryngology. 2013; 2013.
  43. Betti M, Hoseini NH, Martin A, Buccoliero A, Messineo A, Ghionzoli M. Cervical thymic cyst in childhood: a case report. Fetal and Pediatric Pathology. 2015; 34(1):65-9.
  44. Ramareddy RS, Alladi A. Thymic cyst in the differential diagnosis of pediatric lateral cervical masses. Journal of Dr NTR University of Health Sciences. 2012; 1(4):265.
  45. Papoulias I, Mitroudi M, Rafailidis V, Feidantsis T, Theocharides C, Kampouridis P, Kampouridou P, Patoulias D. Fusiform Cervical Mass in a 6-Year Old Boy; Do not Forget the Thymic Cyst. ACTA MEDICA. 2019; 62(3):117-22.
  46. Claes L, Dendooven A, van Heerden J. Challenges in diagnosing ectopic thymus tissue in children. BMJ Case Reports CP. 2019; 12(9):e228807.
  47. De Caluwé D, Ahmed M, Puri P. Cervical thymic cysts. Pediatric surgery international. 2002; 18(5):477-9.
  48. Civantos FJ, Holinger LD. Laryngoceles and saccular cysts in infants and children. Archives of Otolaryngology–Head & Neck Surgery. 1992; 118(3):296-300.
  49. Slonimsky G, Hwang G, Goldenberg D, Gagnon E, Slonimsky E. Terminology, Definitions, and Classification in the Imaging of Laryngoceles. Current Problems in Diagnostic Radiology. 2021; 50(3):384-8.
  50. Ambrus A, Sztanó B, Szabó M, Vasas B, Sziller I, Rovó L. An unusual cause of infant’s stridor–congenital laryngocele. Journal of Otolaryngology-Head & Neck Surgery. 2020; 49(1):1-3.
  51. Yılmaz S, Yıldızbaş Ş, Yaman H, Güçlü E, Öztürk Ö. Stridor in a newborn caused by a congenital laryngocele and bifid epiglottis: A case report and review of the literature. International Journal of Pediatric Otorhinolaryngology Extra. 2010; 5(1):28-31.
  52. Baatenburg de Jong RJ, Rongen RJ, Laméris JS, Knegt P, Verwoerd CD. Ultrasound in the diagnosis of laryngoceles. ORL J Otorhinolaryngol Relat Spec. 1993; 55(5):290-3.
  53. Saha D, Sinha R, Pai RR, Kumar A, Chakraborti S. Laryngeal cysts in infants and children—a pathologist's perspective (with review of literature). International Journal of Pediatric Otorhinolaryngology. 2013; 77(7):1112-7.
  54. Grasso D, Pelizzo G, Bocconi E, Schleef J. Lymphangiomas of the head and neck in children. Acta Otorhinolaryngologica Italica. 2008; 28(1):17.
  55. Maini R, Nagalli S. Lymphadenopathy. StatPearls. Treasure Island (FL): StatPearls Publishing

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  1. Sichel JY, Udassin R, Gozal D, Koplewitz BZ, Dano I, Eliashar R. OK‐432 therapy for cervical lymphangioma. The laryngoscope. 2004; 114(10):1805-9.
  2. Opoko U, Aloua R, Salissou I, Kerdoudi, Hmoura Z, Slimani F. Cervical cystic lymphangioma in a child. Journal of Pediatric Surgery Case Reports. 2021; 71:101919.
  3. Kaira V, Kaira P, Agarwal T. Cervical Cystic Lymphangiomas in Adults: A Case Series of a Rare Entity with Literature Review. Head and Neck Pathology. 2021; 15(2):503-8.
  4. Rauff S, Eng Kien T. Ultrasound Diagnosis of Fetal Neck Masses: A Case Series. Case Reports in Obstetrics and Gynecology. 2013; 2013:243590.
  5. Mittal MK, Malik A, Sureka B, Thukral BB. Cystic masses of neck: A pictorial review. Indian Journal of Radiology and Imaging - New Series (Print). 2012; 22(4):334-43.
  6. Friedman ER, John SD. Imaging of pediatric neck masses. Radiol Clin North Am. 2011; 49(4):617-32, v.
  7. Wong KT, Lee YY, King AD, Ahuja AT. Imaging of cystic or cyst-like neck masses. Clin Radiol. 2008; 63(6):613-22.
  8. Yeo WX, Tan KK. Diagnosis and Surgical Management of Congenital Intranasal Teratoma in a Newborn: A Rare Case Report. Case Rep Otolaryngol. 2018; 2018:1403912.
  9. Chakravarti A, Shashidhar TB, Naglot S, Sahni JK. Head and Neck Teratomas in Children: A Case Series. Indian Journal of Otolaryngology and Head & Neck Surgery. 2011; 63(2):193-7.
  10. Araújo Júnior E, Guimarães Filho HA, Saito M, Pires AB, Pontes AL, Nardozza LM, Moron AF. Prenatal diagnosis of a large fetal cervical teratoma by three-dimensional ultrasonography: a case report. Arch Gynecol Obstet. 2007; 275(2):141-4.
  11. Lahiri AK, Somashekar KK, Wittkop B, Ayshford C. Large Vallecular Masses; Differential Diagnosis and Imaging Features.8:26.
  12. Raftopulos M, Soma M, Lowinger D, Eisman P. Vallecular cysts: a differential diagnosis to consider for neonatal stridor and failure to thrive. JRSM Short Reports. 2013; 4(4):1-3.