Document Type : systematic review
1 1- Assistant Professor of Allergy and Clinical Immunology, Department of Pediatrics, School of Medicine Emam Khomeini Hospital, Ilam University of Medical sciences, Ilam, Iran 2- Assistant Professor of Pediatrics, Department of Pediatrics,
2 Assistant Professor of Pediatrics, Department of Pediatrics, Ilam University of Medical sciences, Ilam, Iran
3 Department of Ophthalmology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran
Background: Retinopathy of prematurity (ROP) is a disease in the retina of premature infants, which is one of the preventable causes of blindness in children.
Objectives: the present study is performed with the purpose of determining the prevalence and outcomes of ROP in Iran through a review method. Systematic and meta-analysis was done.
Study design: All original published articles on the prevalence of ROP in premature infants in Iran were included in the study. On the other hand, intervention articles, meta-analysis, case reports, congress articles, medical dissertations, and articles with low quality were excluded from the study.
Results: 53 articles were included in the meta-analysis stage. Based on the results, the overall prevalence of ROP in Iran was 22.2% (95% CI: 18.5-26.5), the overall prevalence of the disease in ZONE I was 10.5% (95% CI: 3.0-30.6), the overall prevalence of the disease was 45.5% (95% CI: 33.8-57.8) in ZONE II and 43.8% (95% CI: 25.1-64.4) in ZONE III. Regarding the stage of the disease, rate of 39.9% (95% CI: 29.2–51.7) in STAGE I, the rate of 30.3% (95% CI: 21.8–40.5) in STAGE II and the rate of 14.9% (95% CI: 11.0 -19.9) in STAGE III were reported.
Conclusion: Considering the high prevalence of ROP in premature infants in Iran, it is suggested to take necessary preventive measures in this field.
KEYWORDS: Retinopathy, Retinopathy of prematurity, neonatal