Acute lung injury (ALI) is defined as PaO2/FiO2 less than 300 with bilateral pulmonary infiltrates, without pressure is the top of the left atrium. Early diagnosis and treatment of pediatric ALI and find new cases is very important. Accurate diagnosis and effective steps to treating these patients is essential in the outcome of ALI. This study was conducted to show the impact of recruitment in the treatment of ALI patients.
Materials and Methods
This clinical trial study was conducted in Pediatric Educational-Medical center of Tabriz University of Medical Sciences (Tabriz, Iran) and 42 patients with ALI were enrolled. All patients were underwent echocardiography. The patients were divided in 2 groups randomly (intervention and control groups consisted of 21 patients for each group). Patients were followed for 6 months to be evaluated in terms of clinical status and mortality.
Difference on level of PaO2 in intervention group was -26±4 in comparison to the control group which was -4±4 (P<0.05). Difference on time of dependence on mechanical ventilation in intervention group was 8.05±3 in comparison to control group which was 11.05±8 (P<0.05). Mortality rate of intervention group (28%) was lower than the control group (47%)(P<0.05).
Implementation of recruitment could play an important role in decreasing of mortality in patients with acute lung injury.