1 Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 School of Medicine, Zabol University of Medical Sciences, Zabol, Iran.

3 School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.

5 Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.

6 Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.

7 BSc in Operating room, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

8 Social Development & Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.


Children that livingwith addicted parents are at risk for intentionally and unintentionally poisoning. Present study aimed to evaluate the effect of parental addiction on unintentional childhood poisoning.
Materials and Methods: Totally, 140 admitted children with poisoning in Loghman hospital, Tehran-Iran, as referral center were recruited from March 2013 to July 2014. Cases were matched with 280 controls by age (within a caliper of six months), gender, and date of hospital attendance in Tehran, Iran. Parents were interviewed using an objective checklist about the risk factors of childhood poisoning. Conditional logistic regression with within-group varying weights was used to adjust for measured confounders. Vary weights within the matched set was defined by inverse probability weighting (IPW).
Results: Sixty-two of cases (74.7%) were poisoned with Methadone. The odds ratio [OR] 95% confidence interval [CI] of having addicted parents in poisoned children compared to the controls in three scenarios of ordinary, un-stabilized weighted and stabilized weighted conditional regression logistic ORs (95% CI) were 17.3 (8.7, 34.6), 2.6 (1.9, 3.3) and 3.6 (2.9, 4.3) respectively.
The results indicate that child abuse and neglect have been linked to parental substance abuse. Education on preventive interventions such as safe storage of methadone and store poisoning product out of reach and sight of children are necessary in substance abusing families.