1 Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

2 Tuberculosis and Lung Disease Research Center, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Eastern Azerbaijan, Iran.

3 Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.


Background: One of the common side effects of gastroenteritis in children is seizure, which is one of the causes of fever, electrolyte disturbances, and meningitis. This study was aimed to investigate the determinant factors in seizure in children with gastroenteritis and seizure admitted in Tabriz Children's Hospital from 2001 to 2016.
Materials and Methods: This is a descriptive study. The study population included all children admitted with diagnosis of gastroenteritis and seizure in Tabriz Children's Hospital during the years 2001 to 2016. The data of admitted patients including electrolyte disturbances, age, gender, blood-venous analysis, Blood urine nitrogen (BUN), and creatinine tests were extracted from hospital records by a resident and intern of this hospital using a questionnaire designed for this research.
Results: A total of 84 patients were included in the study. The patients included 44 males (52.4%) and 40 females (47.6%). The mean age of the patients was 9.31 ± 7.13 years. Forty-six (55.42%) patients suffered from electrolyte impairment, 24 of which (52.2%) were male and 22 (47.8%) were female; and hyponatremia was the most common disorder (24.10%). Accordingly, only BUN of has proven to be a strong predictor of the likelihood of seizure; also despite of non-significant p-value of PH, it had a potentially strong association with seizure.
According to the results of this study, electrolyte impairment is fairly common in children with acute gastroenteritis. Education about the management of children with seizure to is an important factor in this regard.