International Journal of Pediatrics

Ecballium Elaterium Poisoning in Pediatric Emergency Service: A Case Report

Sinem Sarı Gökay; Özlem Tolu Kendir; Hayri Levent Yılmaz

Volume 6, Issue 1 , January 2018, , Pages 6977-6980

https://doi.org/10.22038/ijp.2017.26634.2292

Abstract

BackgroundEcballium elaterium is the only species belonging to the genus Ecballium of Cucurbitaceae family. It is native to the Mediterranean region. Despite its side effects, E. elaterium ... Read More

The Study Of Diagnostic Value of Elevation of Serum Amylase as a Predictive Factor for Appendiceal Perforation in Children with Acute Appendicitis

Omid Amanollahi; Sakineh Tat

Volume 6, Issue 2 , February 2018, , Pages 7213-7217

https://doi.org/10.22038/ijp.2018.28307.2457

Abstract

BackgroundRecent studies indicate increased serum amylase in children with acute appendicitis. The objective of the current study was to determine the diagnostic accuracy of raised ... Read More

Growth Assessment and Vitamin D Level in Egyptian Juvenile Idiopathic Arthritis Patients

Rasha Abdel-magied; Gihan Omar; Sheren Maher

Volume 7, Issue 8 , August 2019, , Pages 9987-9995

https://doi.org/10.22038/ijp.2019.41070.3460

Abstract

Background Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases in childhood and is frequently associated with growth retardation. Vitamin D is critical ... Read More

The Relationship of Serum Levels of Gamma Interferon and its Receptor (CD119) to Development of BCG Axillary Lymphadenopathy

Mohammad Ali Zamani; Hajar Sorani; Ali Asghar Rabiei; Mehdi Ghatreh-Samani; Soleiman Kheiri; Nika Khoshdel; Abolfazl Khoshdel

Volume 7, Issue 12 , December 2019, , Pages 10595-10603

https://doi.org/10.22038/ijp.2019.44335.3671

Abstract

Background: Lymphadenitis is the most common complication of BCG vaccination in children. Interferon-gamma (IFN-γ) plays a key role in immune response to Mycobacterial infections. ... Read More

A Review on the Relation between Sepsis and Vitamin D Level among Neonatal Intensive Care Unit Infants

Mehdi Mameneh; Seyed Amirreza Akhlagh; Pouya Sharifi; Samaneh Dabagh fekri; Fahimeh Khorasani; Neda Asadi; Farzane Ashrafinia; Saba Safavi

Volume 8, Issue 8 , August 2020, , Pages 11849-11854

https://doi.org/10.22038/ijp.2020.50299.4001

Abstract

Background Neonatal sepsis is a critical condition caused by a generalized bacterial infection in the first month of life. The present study aimed to investigate the relationship between ... Read More

Validation of the Persian Version of Edinburgh Postnatal Depression Scale in Iranian Women

Tahereh Galini Moghadam; Somayeh Moeindarbary; Fatemeh Vafi sani; Alireza Salehi; Atefeh Ahmadi; Fahimeh Khorasani; Masumeh Ghazanfarpour

Volume 8, Issue 9 , September 2020, , Pages 12081-12089

https://doi.org/10.22038/ijp.2020.51174.4063

Abstract

Background The aim of this study is to evaluate the psychometric properties of the Persian versionof the Edinburgh Postnatal Depression(EPDS) among Iranian mothers in postpartum period. ... Read More

Optimization of Health Transformation Plan by Drug Utilization Review Strategy in a Pediatric Teaching Hospital

Parisa Siyarsarai; Kheirollah Gholami; Shekoufeh Nikfar; Shahideh Amini

Volume 8, Issue 11 , November 2020, , Pages 12503-12515

https://doi.org/10.22038/ijp.2020.46414.3778

Abstract

Background: Health transformation planwas implemented in 2014 in Iran with the aim of reducing healthcare expenditures. Transformation plans always have a financial impact on ... Read More Background: Health transformation planwas implemented in 2014 in Iran with the aim of reducing healthcare expenditures. Transformation plans always have a financial impact on healthcare expenditures because of potential to increase the utilization. Drug utilization review is one of the effective solutions to explore consumption and improve rational use. This study aimed to evaluate the medicine utilization after health transformation with implementation of an evidence-based protocol in a tertiary hospital. Materials and Methods: This is a before-after study which was conducted in a tertiary children’s hospital with 400 beds in Iran. At first, costly medications were identified by ABC analysis in drug and therapeutic committee meetings of the hospital. Increased use of these medications was measured after the implementation of the health transformation plan. Then, the pattern of prescription, its appropriateness and impact of protocol implementation on the health expenditures reduction and rational use was evaluated. Results: Initial estimation of the usage showed that before protocol implementation, in six-month, albumin, pantoprazole, and Apotel® increased by 31.9%, 22.6%, and 21.9%, respectively following the health transformation plan. Medical records of 6,554 patients were evaluated for target medications. The frequency of inappropriate prescription reduced significantly from the first to the second phase for albumin (65.5%-35.8%, P=0.001), pantoprazole (58.9%-22%, p <0.001), and Apotel® (66%-17%, p <0.001), respectively. Health expenditures also reduced significantly for albumin (P=0.003), pantoprazole (P=0.001) and acetaminophen (p <0.001), respectively. Conclusion Timely implementation of medication prescription protocols can provide health benefits to patients and cost savings to the health service provider that could lead the health transformation plan to reach the aim of reduction in health expenditures with rational use.

Evaluation of Parental Acceptance of Different Behavior Management Techniques in Pediatric Dentistry, Zahedan, Iran

Elahe sadat Hashemi; Forough Amirabadi; Mostafa Esmaeil Jami

Volume 9, Issue 2 , February 2021, , Pages 13103-13111

https://doi.org/10.22038/ijp.2020.53106.4216

Abstract

Background: Parents play an imperative role in building up their child's attitude towards dentistry. Among the several behavior management techniques, some are more accepted by parents; ... Read More

Tyrosinemia Type III: A Case Report with a Seven Years Follow-up

Saba Vakili; Mohammadreza Emami; Moein Mobini; Rahim Vakili

Volume 9, Issue 6 , June 2021, , Pages 13853-13857

https://doi.org/10.22038/ijp.2021.56791.4451

Abstract

Hereditary tyrosinemia type III (OMIM 276710) is a rare inborn error of tyrosine metabolism caused by the deficiency of 4-hydroxyphenylpyruvate dioxygenase (HPD). This ... Read More

Congenital Rickets: Report of Four Cases

R Vakili; M Saeidi; P Eshraghi; A Ataei Nakhaei; S Vakili; A Khakshour

Volume 2, Issue 2.1 , April 2014, , Pages 22-22

https://doi.org/10.22038/ijp.2014.2474

Abstract

Introduction: Vitamin D deficiency and rickets continue to be health problems in developing countries and most of the infants with congenital rickets may present with hypocalcemic seizure. ... Read More

Pediatric Hematopoietic Stem Cell Transplantation

Amir Ali Hamidieh

Volume 2, Issue 2.3 , May 2014, , Pages 22-22

https://doi.org/10.22038/ijp.2014.2671

Abstract

The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and ... Read More The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in children and adult patients and it is no longer restricted by limited sources of HSCs, donor pools or explicit need for matched family members. Annual number of pediatric HSCTs has been increasing over past two decades and while its growth has become steadier since 2002. Household size and consanguineous marriages in the Middle East means that many pediatric candidates of HSCT can suitable donors among their siblings; however, both of these contributing factors are gradually declining in the region. Iran has been experiencing slower population growth and smaller household sizes since twenty years ago. Hence, according to statements on EMBMT website, Iranian Stem Cell Donor Program (ISCDP) has started its activity in 2010 and has joined Bone Marrow Donors Worldwide (BMDW), in an effort to maximize chances of finding HLA-matched donors in countries in the Eastern Mediterranean Regional Office (EMRO) of World Health Organization (WHO) and beyond. Total body irradiation (TBI) has been used in conditioning from the beginnings of HSCT; however various experiments with non-TBI conditioning regimens have shown an alternative path. Although numerous studies on pediatric HSCT have been published, most patients have had a component of irradiation in their regimens. Long-term detrimental consequences of HSCT, particularly those attributed to TBI, have been continuously studied; endocrine and metabolic abnormalities, growth retardation and short stature and neurocognitive sequel are but a few of these sequel , especially among pediatric recipients. Compared to other studies, non-malignant indications for HSCT constitute a greater proportion of performed HSCTs in Iran; inherited abnormalities of RBCs and thalassemia in particular are responsible for this disparity in part. Keyword: Hematopoietic Stem Cell, Transplantation.

Predictors of Low Birth Weight Infants in the North West Province of Iran: a Case-control Study

Nahid Karamzad; Saeid Safiri; Samira Amiri; Naeema Syedi; Mehrangiz Ebrahimi-Mameghani; Mahmood Moosazadeh; Mostafa Qorbani; Abbas Abbasi-Ghahramanloo

Volume 4, Issue 6 , June 2016, , Pages 1983-1991

https://doi.org/10.22038/ijp.2016.6949

Abstract

Background: Ninety-five percent of low birth weight infants are born in developing countries. This study was aimed to assess the predictors of low birth in East Azerbaijan, North-west ... Read More

Comparing the Outcomes of IVIg with Combination of IVIg and Methylprednisolone in Children with Acute Idiopathic Thrombocytopenia; a Bayesian Logistic Approach

Seyed Kamal Eshagh-Hoseini; Shahram Arsang-Jang; Tohid Jafari-Koshki

Volume 4, Issue 7 , July 2016, , Pages 2221-2228

https://doi.org/10.22038/ijp.2016.7096

Abstract

Background This study aimed to evaluate the effectiveness of Intravenous immunoglobulin (IVIg) and combination of IVIg and Methylprednisolone for childhood Idiopathic (autoimmune) Thrombocytopenia ... Read More

Vitamin D Status in Children with Iron Deficiency and/or Anemia

Esraa Arjumand Qader; Nazdar Ezzaddin Alkhateeb

Volume 4, Issue 9 , September 2016, , Pages 3571-3577

https://doi.org/10.22038/ijp.2016.7482

Abstract

Background Iron and vitamin D inadequacy are both essential wellbeing issues, an extra advancement has been the vitamin D extra skeletal role. Late collecting proof demonstrates that ... Read More

Comparative Study on the Effect of Risperidone and its Combination with Naltrexone in Pediatric Patients with Autistic Spectrum Disorders: A Clinical Trial Study

Fatemeh Moharreri; Ebrahim Abdollahian; Seyedeh Azam Hosseini; Mansoureh Mirzadeh

Volume 5, Issue 12 , December 2017, , Pages 6375-6382

https://doi.org/10.22038/ijp.2017.18557.1516

Abstract

Background Autistic spectrum disorder (ASD) refers to a syndrome associated with persistent impairments in communication skills, social interactions, and so forth. Given the approval ... Read More

Ossified Sacrotuberous Ligament and its Clinical Significance: A Case Report

Yuvaraj Maria Francis; Priyadarshini Anna Durai; Sanjana Rajkumar; Sankaran PonuswamyKasiragan; Gunapriya Raghunath; Kumaresan Munuswamy; Begum Zareena

Volume 6, Issue 1 , January 2018, , Pages 6981-6985

https://doi.org/10.22038/ijp.2017.26545.2283

Abstract

The present study describes the morphometry of a unilateral ossified sacrotuberous ligament. It aims to discuss its Anatomical and clinical implications.The pudendal nerve, internal ... Read More

Epidemiology of Maternal and Fetal`s Burn in Iran: A Systematic Review and Meta-Analysis

Abbas Aghaei; Bahare Lotfi; Zahra Shaahmadi; Behzad Karami-Matin; Touraj Ahmadi jouybari

Volume 6, Issue 2 , February 2018, , Pages 7219-7240

https://doi.org/10.22038/ijp.2018.28674.2499

Abstract

Background: Burn is one of the public health problems, especially in low-income and middle-income countries, and this problem is far more important for pregnant women and their fetus. ... Read More

Cystic Fibrosis Patients Evaluation in the Last Decades in a Referral Center, Tehran-Iran

Maryam Hassanzad; Masoumeh Ansari; Ali Valinejadi; Seyed Javad Sayedi; Ali Akbar Velayati

Volume 7, Issue 8 , August 2019, , Pages 9997-10007

https://doi.org/10.22038/ijp.2019.40329.3416

Abstract

Background Cystic fibrosis (CF) is the most prevalent lethal chronic genetic and multivariate disease, widespread in Iranian population. The aim of this study was to evaluate the condition ... Read More

Aspergillus Fumigatus Endocarditis after Total Correction of Tetralogy of Fallot

Mohamad Mahdavi; Feisal Rahimpour; Mahmood Hosseinzadeh Maleki

Volume 7, Issue 12 , December 2019, , Pages 10605-10609

https://doi.org/10.22038/ijp.2019.41338.3488

Abstract

There are few studies about post-cardiac surgery fungal infections especially by Aspergillus fumigatus. In this paper we report a case of Aspergillus fumigatus endocarditis after ... Read More

A Patient with Tuberous Sclerosis Complex and Spinal Muscular Atrophy; A Case Report

Sina Raeisi; Hassan Bakhtiary; Mohammad Barzegar

Volume 8, Issue 8 , August 2020, , Pages 11855-11860

https://doi.org/10.22038/ijp.2020.49604.3967

Abstract

Background Tuberous Sclerosis Complex (TSC), and Spinal Muscular Atrophy (SMA) are two inherited disorders while they are genetically independent. TSC is characterized by the formation ... Read More

Factors Related to the Age at Menarche in Iran: A Systematic Review and Meta-Analysis

Saeideh Nasiri; Mahrokh Dolatian; Fahimeh Ramezani Tehrani; Hamid Alavi Majd; Azam Bagheri; Pooneh Malekifar

Volume 8, Issue 9 , September 2020, , Pages 12091-12104

https://doi.org/10.22038/ijp.2020.49222.3939

Abstract

Background Reduced age at menarche is an important health indicator for women and may be associated with complications such as an increased risk of asthma, breast cancer, ovarian cancer, ... Read More

Role of Food Allergy in Development of Different Levels of Asthma Severity in Childhood

Parnia Poursadri; Mahboubeh Mansouri; Amirnezam Mir; Seyedeh Niloofar Hashemi; Seyed Karen Hashemitari; Sepideh Darougar

Volume 9, Issue 6 , June 2021, , Pages 13859-13864

https://doi.org/10.22038/ijp.2020.52493.4167

Abstract

Background Various risk factors, including previous history of food allergy, may play an important role in predicting the development and the outcome of asthma in children. This study ... Read More

Determinants of Nutritional Status in Children living in Mashhad, Iran

T Shafieian; LA Latiff; MH Soo Lee; M Mazidi; M Ghayour Mobarhan; G Tabatabaei; G Ferns

Volume 2, Issue 2.1 , April 2014, , Pages 23-23

https://doi.org/10.22038/ijp.2014.2476

Abstract

Introduction: Children are one of the most vulnerable groups to sub-optimal nutritional intake in most societies. We have investigated some of the potential determinants of malnutrition ... Read More

Hematopoietic Stem Cell Transplantation for Thalassemia

Ali Ghasemi

Volume 2, Issue 2.3 , May 2014, , Pages 23-23

https://doi.org/10.22038/ijp.2014.2672

Abstract

Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic ... Read More Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and hepatic damage. Without transfusions, thalassemic patients have tremendous skeleton deformities, as well as hepatomegaly and splenomegaly due to expansion of the hematopoietic system with extramedullary hematopoiesis. Allogeneic hematopoietic stem cell (HSC) transplantation (HSCT) in thalassemia has been a cornerstone in the development of HSCT. The rational basis of HSCT in thalassemia consists of substituting the thalassemic HSC bearing ineffective erythropoiesis with an allogeneic one capable of effective erythropoiesis. This cellular replacement therapy is not limited to the diseased erythropoietic component, but leads to the replacement of the entire hematopoietic system. Nevertheless, it is an efficient way to obtain a long-lasting, probably permanent, clinically effective correction of hemolytic anemia, thus avoiding transfusion requirements and associated complications . The transplantation approach for a nonmalignant disease is much different from transplantation in malignancies. In the former setting, the detrimental immunologic proprieties [GVHD] of the engrafted HSC are not balanced by an antimalignancy effect. This characteristic must be always considered in determining the risk/benefit ratio and therapeutic decision such as the kind and intensity of the conditioning regimen, GVHD prophylaxis, source of HSC, and adoptive posttransplant therapies. The Pesaro group developed a prognostic scheme to predict transplant outcome in patients younger than age 17. This prognostic scheme included three variables all related to iron burden: quality of chelation received for the entire life before transplantation; hepatomegaly; and the presence of liver fibrosis at pretransplant hepatic biopsy examination. These variables stratified patients into three groups based on them having none, or one/two, or all three of the risk factors. Overall survival and thalassemia-free survival were significantly different in the three groups: 94% and 87% in the low-risk group, 84% and 81% in the intermediate-risk group, and 70% and 58% in the high-risk group, respectively. The rate of rejection/thalassemia recurrence was much higher in thalassemic patients than in patients transplanted because of malignancies. Several factors have been invoked to explain this difference: massive pretransplant exposure to blood products, not having received any chemotherapy before transplant, expanded erythropoietic marrow, and possibly splenomegaly. Key Words: Hematopoietic, Stem cell, Thalassemi.

The Comparison of Iranian and Foreign Students’ Motivations to Choose Dentistry Field of Study

Abdolreza Gilavand

Volume 4, Issue 6 , June 2016, , Pages 1993-2010

https://doi.org/10.22038/ijp.2016.6861

Abstract

Background Because of some special and privileged attractions of dentistry discipline, the first choice of volunteers who want to enter university is dentistry. The students usually ... Read More

Volume 12 (2024)

Volume 11 (2023)

Volume 10 (2022)

Volume 9 (2021)

Volume 8 (2020)

Volume 7 (2019)

Volume 6 (2018)

Volume 5 (2017)

Volume 4 (2016)

Volume 3 (2015)

Volume 2 (2014)

Volume 1 (2013)

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