International Journal of Pediatrics

Evaluation of Gluten-free Diet on the Heart Functions in Children with Celiac Disease

Noor Mohammad Noori; Alireza Teimouri; Touran shahraki

Volume 7, Issue 1 , January 2019, , Pages 8889-8905

https://doi.org/10.22038/ijp.2018.33947.2993

Abstract

Background Celiac disease (CD) is an autoimmune mediated gluten sensitive enteropathy and a chronic inflammatory condition caused by immune pathology in the small intestines in genetically ... Read More Background Celiac disease (CD) is an autoimmune mediated gluten sensitive enteropathy and a chronic inflammatory condition caused by immune pathology in the small intestines in genetically susceptible individuals. This study aimed to determine the efficacy of gluten free diet on cardiac functions using conventional and Doppler tissue echocardiography (DTE) in children with CD compared to controls. Materials and Methods This case-control study was conducted on 107 children with CD and 45 healthy children. The study was performed in the Ali Ebne Abi Talib hospital, affiliated to Zahedan University of Medical Sciences, Zahedan (ZaUMS), Iran. After considering exclusion criteria, participants underwent echocardiography. Data were analyzed through SPSS software version 20.0. Results: Results showed that tTG-IgA was different in participants. Left MPI was different in control-positive (p<0.001), control-newly diagnosed (p=0.024), and positive-negative (p<0.001). Right MPI was different in control-positive (p<0.001), control-newly diagnosed (p=0.024), positive-negative (p<0.001), and negative-newly diagnosed (p<0.001). Left MPI’ was different in control-positive (p<0.001), control-newly diagnosed (p<0.001), positive-negative (p=0.014), and negative-newly diagnosed (p=0.010). Right MPI’ was different in control-positive (p<0.001), control-newly diagnosed (p<0.001), positive–negative (p=0.010), and negative-newly diagnosed (p=0.034). Left DT was different in positive-negative. Right ET was different in control-positive, control-newly diagnosed, positive-negative and negative-newly diagnosed. Right AT was different in positive-negative and positive-newly diagnosed. Conclusion It was concluded in patients with positive response to gluten free diet that some heart functions were similar to the controls and in patients with negative response, some were similar to newly diagnosed patients. Diastolic and systolic dysfunctions are important findings in CD children and TDE is a better method to identify cardiac involvements in subclinical patients with CD.

Doppler Tissue Echocardiography and Electrocardiography in Children with Celiac Disease Compared to Controls

Noor Mohammad Noori; Alireza Teimouri; Iraj shahramian; Turan Shahraki

Volume 6, Issue 11 , November 2018, , Pages 8561-8578

https://doi.org/10.22038/ijp.2018.32405.2855

Abstract

Background Celiac disease (CD) is an autoimmune mediated gluten sensitive enteropathy and characterized by a wide range of clinical manifestations. The study aimed to compare Doppler ... Read More

The Prevalence of Celiac Disease in Down syndrome Children with and without Congenital Heart Defects

Noor Mohammad Noori; Alireza Teimouri; Maryam Nakhaey Moghaddam; Touran Shahraki

Volume 4, Issue 7 , July 2016, , Pages 2143-2152

https://doi.org/10.22038/ijp.2016.7041

Abstract

Background The prevalence of celiac disease (CD) is remarkably varied in Down syndrome(DS)patientscompared with other diseases. This study aimed to assess celiac disease prevalence ... Read More

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Author = Turan Shahraki

Evaluation of Gluten-free Diet on the Heart Functions in Children with Celiac Disease

Abstract

Doppler Tissue Echocardiography and Electrocardiography in Children with Celiac Disease Compared to Controls

Abstract

The Prevalence of Celiac Disease in Down syndrome Children with and without Congenital Heart Defects

Abstract