International Journal of Pediatrics

Perinatal Outcomes of Idiopathic Polyhydramnios with Normal Ultrasound: A Systematic Review and Meta-Analysis

Samiyeh Kazemi; Farin Soleimani; Sara Kazemi; Anoshirvan Kazemnezhad; Zahra Kiani; Farzaneh Pazandeh; Nasrin Azimi

Volume 7, Issue 5 , May 2019, , Pages 9349-9362

https://doi.org/10.22038/ijp.2018.36148.3155

Abstract

Background: Incidence of polyhydramnios in various studies has been reported from 0.2 to 3.9%. Approximately, 50-60% of cases are idiopathic with no known etiology. We aimed to investigate ... Read More Background: Incidence of polyhydramnios in various studies has been reported from 0.2 to 3.9%. Approximately, 50-60% of cases are idiopathic with no known etiology. We aimed to investigate perinatal outcomes of idiopathic polyhydramnios with a normal ultrasound. Materials and Methods: In this study, Persian and English databases including Barakatkns, SID, Magiran, Medline, Science Direct, Scopus, Cochran, Embase, and ProQuest were searched for articles published from 1950 to August 2018. The search procedure was conducted with keywords related to "idiopathic polyhydramnios", "perinatal outcomes", "normal ultrasound", and their equivalents in "Mesh" and PICO. In meta-analysis, first we quantified heterogeneity by using I2 statistics and tested using the Cochran’s Q test. Even when a low heterogeneity was detected, a fixed-effects model was applied, and for more than 75% of heterogeneity, random-effects model was used. The Forest Plot chart was drawn up and the relative risk (RR) estimate for each study (ES), the pooled estimate of "RR" by combining all the studies and its 95% CI, and the P-value associated with it, were indicated. Results: In this study, 13 articles involving 325,426 pregnant women were included for the Meta-analysis. The RR and 95% CI of Caesarian Section (C.S), 1.61(1.25-2.07), macrosomia, 1.84(1.40-2.42), preterm delivery, 2.45(1.29-4.64), NICU admission, 2.90(1.77-4.74), Apgar score min 5 <7, 2.79(1.18-6.57), fetal distress, 1.69(1.02-2.80), and large for gestational age (LGA), 2.27(1.38-3.72), were determined. We found a higher RR of perinatal outcomes including NICU admission, Apgar score min 5<7, preterm delivery, and LGA. RR other perinatal outcomes such as macrosomia, fetal distress, and C.S. were lower. Conclusion: Idiopathic Polyhydramnios was significantly associated with adverse perinatal outcomes. Intensive intrapartum monitoring and further attention in the postpartum are warranted.

Perinatal Outcome in Multiple versus Singleton Pregnancies in Neonates Born in Fatemieh Hospital of Hamadan, Iran

Mohammad Kazem Sabzehei; Behnaz Basiri; Maryam Shokouhi; Fatemeh Eghbalian

Volume 5, Issue 8 , August 2017, , Pages 5493-5500

https://doi.org/10.22038/ijp.2017.23647.1995

Abstract

Background: Multiple pregnancies are responsible for the increased risk of maternal and neonatal morbidity and mortality. This study aimed to compare the perinatal outcome between multiple ... Read More Background: Multiple pregnancies are responsible for the increased risk of maternal and neonatal morbidity and mortality. This study aimed to compare the perinatal outcome between multiple and singleton pregnancies. Materials and Methods: This is a retrospective cohort study. A sample of 50 multiple birth neonates- born in Fatemieh Hospital of Hamadan, Iran in 2015- was selected using simple random sampling. Meanwhile, they were compared with 50 single birth neonates in the same center on gender, gestational age, mean birth weight, Apgar score, the use of Assisted Reproductive Techniques (ART), delivery method, cause of neonatal admission, duration and short outcome of neonatal hospitalization. The data were collected from the medical files of neonates and their mothers. The data were analyses using SPSS version 16.0 software. Results: In this study, 100 neonates (50 single births and 50 multiple births) were compared. The mean gestational age and mean birth weight of multiple births were lower than that of single births (P<0.05). The frequency of low birth weight was 4%, 95.5%, and 100% among the single births, twins, and triplets, respectively. A significant difference was also found between multiple and single births on 1-Minute and 5-Minute mean Apgar scores, neonatal hospitalization after birth, hyperbilirubinemia, respiratory distress syndrome (RDS), the need for mechanical ventilator, antibiotics intake and phototherapy (P<0.05). Frequency of gestational diabetes and preeclampsia were greater in multiple pregnancies than single ones; however, the difference was not significant (P>0.05). A significant difference was found on the frequency of in vitro fertilization (IVF) method, rate of cesarean section and preterm delivery (P<0.05). Conclusion: In this study, multiple pregnancies were associated with maternal complications including preterm delivery and the increased cesarean section rate, and neonatal complications such as low birth weight, prematurity and increased rate of neonatal hospitalization that increases risk of perinatal morbidity and mortality.

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Keywords = Perinatal outcome

Perinatal Outcomes of Idiopathic Polyhydramnios with Normal Ultrasound: A Systematic Review and Meta-Analysis

Abstract

Perinatal Outcome in Multiple versus Singleton Pregnancies in Neonates Born in Fatemieh Hospital of Hamadan, Iran

Abstract