International Journal of Pediatrics

Effect of Fluoxetine Therapy on Breath-Holding Spells in Children: A Clinical Trial Study

Seyedeh Zahra Farzadfard; Farah Ashrafzadeh; Mehran Beiraghi Toosi; Hassan Mahrad Majd; Mahinosadat Shahabifar

Volume 8, Issue 1 , January 2020, , Pages 10775-10783

https://doi.org/10.22038/ijp.2019.44287.3670

Abstract

Background: Breath-holding spells (BHS) is a sudden and reflexive phenomenon that is common in infancy and early childhood. Despite the harmless nature of BHS, being subjected to this ... Read More Background: Breath-holding spells (BHS) is a sudden and reflexive phenomenon that is common in infancy and early childhood. Despite the harmless nature of BHS, being subjected to this phenomenon is very stressful for parents and sometimes requires treatment. In this study, we evaluated the efficacy of fluoxetine therapy (as an anxiolytic medication) on pediatric BHS. Materials and Methods: The present clinical trial study was carried out on 30 patients with BHS referring to Neurology Clinic of Ghaem Hospital, Mashhad, Iran, in 2018. The subjects were randomly divided into control (n = 15), and intervention (n= 15) groups. The control group was then treated with iron and the intervention group with iron and fluoxetine for 3 months. The frequency and duration of BHS before and after treatment were compared in both groups. The results were later analyzed using SPSS version 16.0. Results: The present study was carried out on 30 children. The mean of infants’ age in the control and intervention groups was 20.26 ± 5.8 and 22.46 ± 5.2 months, respectively (P>0.05). The mean frequency and the duration of BHS decreased from 8.2 ± 4.3 to 1.6 ± 2.4 times per week (p = 0.000), and from 50.66 ± 26.26 to 5.4 ± 6 seconds (p = 0.000) in the control group; and from 7.2 ± 3 to 2.06 ± 2.7 times per week (p = 0.001), and 50.66 ± 38 to 8.8 ± 7.9 seconds (p = 0.002) in the intervention group, which was indicative of a statistically significant difference. However, the difference in the mean frequency and duration of BHS in the intervention group, which represents the effect of fluoxetine, was not statistically significant (p = 0.411 and p = 0.792, respectively). Conclusion: The results of the present research confirm the effect of iron therapy on decreasing the mean frequency and duration of BHS, but also indicate the ineffectiveness of synergistic administration of fluoxetine and iron on decreasing mean frequency and duration of BHS.

Effects of Iron in Neonates and Young Infants: a Review

Gian Maria Pacifici

Volume 4, Issue 7 , July 2016, , Pages 2256-2271

https://doi.org/10.22038/ijp.2016.6991

Abstract

Iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. Iron is absorbed by the duodenum and requires an acidic environment for optimal ... Read More

Maternal Knowledge and Performance about Use of Iron and Multivitamin Supplements in Children in Northwest of Iran

Babak Abdinia

Volume 2, Issue 2.2 , April 2014, , Pages 119-123

https://doi.org/10.22038/ijp.2014.2438

Abstract

Introduction Micronutrients deficiency, especially iron and vitamins, is a common nutritional problem among children under 2 years in Iran. The aim of the present study is to assess ... Read More

Iron and Multivitamin Supplements in Children and its Association with Growth rate

Masumeh Saeidi; Rahim Vakili; Ali Khakshour; Habibolah Taghizadeh Moghaddam; Mohammad Ali Kiani; Behjat Zarif; Somayeh Nateghi

Volume 1, Issue 1 , August 2013, , Pages 13-17

https://doi.org/10.22038/ijp.2013.2028

Abstract

Introduction: Vitamin deficiency and iron deficiency anemia are common nutritional problems, at least in children under 5. These materials shortage, especially in the first two years ... Read More Introduction: Vitamin deficiency and iron deficiency anemia are common nutritional problems, at least in children under 5. These materials shortage, especially in the first two years of life, impair physical and brain growth, reduces the child's learning ability, reduces body resistance against infections, behavioral changes, apathy and finally social and economic adverse consequences would be followed. This study aimed to determine the supplements used in children under two years and its Association with Growth rate in Mashhad City. Materials and Methods: In this cross-sectional descriptive study , 300 children 6 to 24 months were recruited in health centers in Mashhad, Data was collected from mother and and children’ records and valid and reliable questionnaire was used to collect data. The data was analyzed by statistical tests and SPSS 11.5 and P Results: Results showed that 13.7 percent of families were with low income, 82.7 percent middle income and 3.7 percent well income. In growth chart, 86.7 percent of children showed appropriate growth, 10.3 percent had delayed growth and 3 percent had horizontal growth curve .In 80.7 percent of families, maternal multivitamin and iron drops have been used to their children regularly, 1.7 percent did not believe in these supplements and 17.7 percent of mothers sometimes used these supplements for their children. Results also showed statistical correlation significant variables of parental education, family income, mothers referred to health centers for monitoring the growth and get face to face training of personnel center drops of multivitamin with iron and growth status of children variable is available, so children who regularly have used supplements and income level and above are literate parents have grown more favorable than the other kids (P<0.05). Conclusion: Regarding the importance of iron and multivitamin use in children under two years, necessary training must be provided to mothers in this field by health centers personnel. Meanwhile, it is recommended that the authorities must distribute periodical and enough drops to health centers.

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Keywords = Iron

Effect of Fluoxetine Therapy on Breath-Holding Spells in Children: A Clinical Trial Study

Abstract

Effects of Iron in Neonates and Young Infants: a Review

Abstract

Maternal Knowledge and Performance about Use of Iron and Multivitamin Supplements in Children in Northwest of Iran

Abstract

Iron and Multivitamin Supplements in Children and its Association with Growth rate

Abstract