Background: This study aimed to assess the symptoms and clinical laboratory data of pregnant women with COVID-19 in their second or third trimester of pregnancy as well as their maternal and neonatal outcomes.
Methods: This retrospective observational study was conducted on 177 pregnant women with COVID-19 who were admitted to Yas hospital (affiliated with Tehran University of Medical Sciences), and AliIbne Abitaleb hospital (affiliated with Zahedan University of Medical Sciences).
Results: There was significant higher complaints including fever (p-value=0.015), cough (p-value=0.028), fatigue (p-value=0.002), dyspnea (p-value=0.022), and lower hemoglobin level (p-value=0.009) in patients who were in their third trimester regardless of their who were in their second trimester.
Of the patients, 9.6% (n=17) had severe disease and needed ICU admission. There was a significant variation regarding gestational age (p-value=0.022) in pregnant women admitted to ICU compared to the other ones. During the study, delivery happened in 108 (61%) pregnant women. Fetal distress following meconium deification (p-value=0.041), need to MGSO4 (p-value=0.001), IUFD (p-value=0.006), need for blood transfusion (p-value=0.004), and neonatal death (p-value<0.001) in patients who needed ICU admission were significantly higher.
Conclusion: Higher gestational weeks are the main risk factor for severe COVID-19 disease. Although the vertical transmission is rare; due to the higher risk of perinatal outcomes, the delivery should be done in a center with NICU department.