International Journal of Pediatrics

original article

Pulse Oximetry Screening for Detecting Congenital Heart Disease in Neonates – Experience from Tertiary Referral Children’s Hospital in South India

Ashwini R C; Sushil Kumar K; Shashidhar Sankratti; Mugangowda Patil

Volume 12, Issue 3 (In Progress) , March 2024, Pages 18620-18627

https://doi.org/10.22038/ijp.2024.77015.5408

Abstract

Background: Congenital heart disease is the most common type of birth defect in infancy with incidence of 8 to 12 per 1000 live births in India. Pulse oximetry has emerged as a good ... Read More Background: Congenital heart disease is the most common type of birth defect in infancy with incidence of 8 to 12 per 1000 live births in India. Pulse oximetry has emerged as a good screening tool in the recent past in many countries being noninvasive and cost effective. This study aimed at estimating the accuracy of pulse oximetry as a standard screening method to detect congenital heart diseases (CHD) in neonates. Methods: This prospective observational study was conducted in a tertiary referral medical college hospital from December 2018 to June 2020. Pulse oximetry readings were taken of 1603 asymptomatic neonates breathing in room air from right hand and either foot after 24 hours of birth. Pulse oximetry was considered positive if oxygen saturation in room air measured <95% or difference between right hand and foot was more than 3% persistently for 3 readings as per the standard American Academy of Pediatrics algorithm. Neonates with positive pulse oximetry or those with persistent abnormal clinical examination underwent echocardiography. Results: Of the term neonates (n=1603) screened, incidence of CHD was 0.7 per 1000 live births and critical CHD was 0.3 per 1000 live births. The sensitivity, specificity, positive predictive value, and negative predictive value of pulse oximetry to detect any CHD were 70.6%, 98.8%, 38.7%, and 99.7%, major CHD was found to be 60%, 98.4%, 19.4%, and 99.7%, and critical CHD to be 85.7%, 98.4%, 19.4%, and 99.9%, respectively. Pulse oximetry had significant positive correlation with abnormal clinical examination (R=0.29, p<0.001) and ECHO findings in detecting CHD (R=0.49, p<0.001). Regression model to evaluate whether abnormal clinical examination and positive pulse oximetry are significant predictors of CHD detected by ECHO was statistically significant (R2 =0.34, p value <0.001) and both were significant independent predictors (p<0.001). Conclusion: Pulse oximetry screening is a useful tool for detecting congenital heart diseases in newborns.

original article

Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants

Raheleh Faramarzi Garmroudi; Feisal Rahimpour; Maryam Aghdasi; Maryam Emadzadeh; Hassan Mottaghi Moghaddam shahri; Maryam Moradian; Reza Saeidi; elahe Heidari

Volume 12, Issue 3 (In Progress) , March 2024, Pages 18628-18636

https://doi.org/10.22038/ijp.2024.78701.5435

Abstract

Background: Perinatal asphyxia may cause multiple organ dysfunctions, including myocardial dysfunction. This study aimed to evaluate the prevalence and features of myocardial dysfunction ... Read More

original article

Associations between Prenatal Exposure to Air Pollutants and Cord-Blood Thyroid Hormones Levels: A Cross-Sectional Study in Isfahan

Elahe Golverdi; Mahin Hashemipour; Silva Hovsepian; Mehri Khoshhali; Roya Kelishadi

Volume 12, Issue 3 (In Progress) , March 2024, Pages 18637-18648

https://doi.org/10.22038/ijp.2024.79827.5454

Abstract

Background: Air pollution as a major health concern in the world can adversely affect pregnant women and their newborns' thyroid function. We evaluated the association between prenatal ... Read More

original article

Lactate Dehydrogenase as a New Prognostic Factor for Mortality in Multisystem Inflammatory Syndrome in Children

Aida Askarisarvestani; Seyed Hesamedin Nabavizadeh; Mina Esmailli; Soheila Alyasin; Hossein Esmaeilzadeh

Volume 12, Issue 3 (In Progress) , March 2024, Pages 18649-18658

https://doi.org/10.22038/ijp.2024.80040.5455

Abstract

Background: Multisystem Inflammatory Syndrome in Children (MIS-C) is a rather newly described entity that can potentially end in multisystem failure in children following COVID-19 infection. ... Read More

original article

Personal Protective Equipment and Hand Hygiene Status in Health Care Workers during the Covid-19 Pandemic

Mahboubeh Dordipour; Mohammad Hasan Aelami; Mohsan Raza; Seyyed Parham Ahmadi; Mehran Mansouri; Arsha Khaleghi; Yousof Hajipour; Fatemeh Pelian; Nafiseh pourbadakhshan

Volume 12, Issue 3 (In Progress) , March 2024, Pages 18659-18668

https://doi.org/10.22038/ijp.2024.81187.5466

Abstract

Background: The COVID-19 pandemic presents a major risk to Health Care Workers (HCWs), which necessitates protective strategies. Personal Protective Equipment (PPE) and Hand Hygiene ... Read More

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Volume & Issue: Volume 12, Issue 3 (In Progress), March 2024

Pulse Oximetry Screening for Detecting Congenital Heart Disease in Neonates – Experience from Tertiary Referral Children’s Hospital in South India

Abstract

Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants

Abstract

Associations between Prenatal Exposure to Air Pollutants and Cord-Blood Thyroid Hormones Levels: A Cross-Sectional Study in Isfahan

Abstract

Lactate Dehydrogenase as a New Prognostic Factor for Mortality in Multisystem Inflammatory Syndrome in Children

Abstract

Personal Protective Equipment and Hand Hygiene Status in Health Care Workers during the Covid-19 Pandemic

Abstract